Protein Alignment CG31445 and Rnpepl1

DIOPT Version :10

• Sequence 1: NP_651689.1
• Gene: CG31445 / 326140
• FlyBaseID: FBgn0051445
• Length: 927
• Species: Drosophila melanogaster
• Sequence 2: NP_852070.3
• Gene: Rnpepl1 / 108657
• MGIID: 1914170
• Length: 720
• Species: Mus musculus
• Alignment Length: 805
• Identity: 186/805 - (23%)
• Similarity: 293/805 - (36%)
• Gaps: 209/805 - (25%)

  Fly    13 LDLSVANS--ISRYNHYRLPTALRPQR------YYLRILTLLESPDDLRFAGNVQIVIKALQNTR 69
            ||::.|:|  :.|..|.:|...|||:.      ..|.:..|..:|..|        |:.|....|
Mouse    28 LDVASASSAQLFRLRHLQLGLELRPEARELAGCLVLELCALRPAPRAL--------VLDAHPALR 84

  Fly    70 NITLHSKNL----TIDESRITLR-QISGAG------------NMDNCVSSTSVNPTHDYYIFHTC 117
               |||.:.    .:.||..|.. ...|:|            ...:|..:..::|..||....|.
Mouse    85 ---LHSVSFRRASAVSESPCTFAFPAPGSGPPLPGFADAPGAESASCPLAFRLDPFTDYGSSLTV 146

  Fly   118 ---KELLAGNVYKLFLPFSADLTPQLFGYYRSSYKDP--VTNKTRWLSATQFEPSSARKAFPCFD 177
               .|:.|...:::.|.:::...|.::      :.||  .....:....||......|..|||||
Mouse   147 TLPPEVQAHQPFQVILRYTSTDAPAIW------WLDPELTYGNAKPFVFTQGHSVCNRSFFPCFD 205

  Fly   178 EPGFKASFVVT----LGYHKQFNALSNMPVREIRPHESLANYIWCEFQESVPMSTYLVAYSVNDF 238
            .|..|.::...    ||.....:|..::.|.|    |.|.:     |....|:..||||....|
Mouse   206 TPAVKCTYSAVVKAPLGVQVLMSATQSVYVEE----EGLYH-----FHMEHPVPAYLVALVAGD- 260

  Fly   239 SFKPSTLPNGALFRTWARP-----------NAIDQCDYAAE--FGPKVLQYYEEFFGIRYPLPKI 290
             .||:.:  |...|.||.|           .|::|...|||  :||.:...|:..|     ||
Mouse   261 -LKPADI--GPRSRVWAEPCLLPTATSKLSGAVEQWLSAAERLYGPYMWGRYDIVF-----LP-- 315

  Fly   291 DQMAVPDFSAGAMENWGLVKYRESTLLYSPTHSSLADKQDLANVIAHELAHQWFGNLVTMKWWTD 355
                 |.|...||||..|      |.:.|   |.|...:.|...:.||:||.||||.||...|.:
Mouse   316 -----PSFPIVAMENPCL------TFIIS---SILESDEFLVIDVIHEVAHSWFGNAVTNATWEE 366

  Fly   356 LWLNEGFATYVAGLGVQEIYPEWHSRDKGSLTALMTAFRLDS-------LVSSHPISR-PIQMVT 412
            :||:||.|||.......|.|       ..:.|.|.||||||:       |....|:|: .:::..
Mouse   367 MWLSEGLATYAQRRITTETY-------GAAFTCLETAFRLDALHRQMRLLGEDSPVSKLQVKLEP 424

  Fly   413 EIEES--FDAISYQKGSA-VLRMMHLFMGEESFRTGLREYLKLYAYKNAEQNNLWESLTTAAHQN 474
            .:..|  .:..:|:||.. |..:..|..|.:.|...||.|::.|.:.:....:|.:|..:...:.
Mouse   425 GVNPSHLMNLFTYEKGYCFVYYLSQLCGGPQRFDDFLRAYVEKYKFTSVVAQDLLDSFLSFFPEL 489

  Fly   475 GALPGHYDINTIMDSWTLQTGFPVLNITRDYSTGTAEITQERYLRNSQIPQADRVGCWWV-PLSY 538
            .............:.|...||.|:..  .|.|.|:: :|:         |.......|.. ||..
Mouse   490 KEQSVDCRAGLEFERWLNATGPPLAE--PDLSQGSS-LTR---------PVEALFQLWTAEPLEQ 542

  Fly   539 TTQDENDFNNTSPKAWMECSSTDEGVPTTIDHSAGPEEWLILNIQLSTPYKANYDARNWKLLIDT 603
            .....:..:.:..:.:......|.    .:|.|..|:|   :.:.||..|.:         |:|:
Mouse   543 AAASASAIDISKWRTFQTALFLDR----LLDGSPLPQE---VVMSLSKCYSS---------LLDS 591

  Fly   604 LNSKDFQSIHVINRAQLIDDVLYFAWTGEQDYETALQVTNYLRRERDLIPWKSALDNLKLLNRIL 668
            :|::                 :...|         ||:.    ...|..|      :|..:.|.|
Mouse   592 MNAE-----------------IRIRW---------LQIV----VRNDYYP------DLHRVRRFL 620

  Fly   669 RQTPNFGSFKRYMQKLLT-PIYEHL-HGMNDTFSLMTQQDEVL----------LKTTVVNVACQ- 720
                     :..|.::.| |:||.| .|...:|:|     ||.          |:.|:..:..|
Mouse   621 ---------ESQMSRMYTIPLYEDLCTGALKSFAL-----EVFYQTQGRLHPNLRRTIQQILSQG 671

  Fly   721 -YDVSDCVTQAQAYFRRWRAETNPD 744
             ...::..|:.........|:||||
Mouse   672 LGPSAEPSTEPSTDLGGAEADTNPD 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31445	NP_651689.1	M1_APN-Q_like	37..492	CDD:341064	126/510 (25%)
		ERAP1_C	577..905	CDD:463368	34/182 (19%)
Rnpepl1	NP_852070.3	M1_LTA4H	29..507	CDD:341062	135/535 (25%)
		Leuk-A4-hydro_C	555..668	CDD:462686	32/178 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	671..708		6/26 (23%)