Protein Alignment CG31445 and rnpepl1

DIOPT Version :10

• Sequence 1: NP_651689.1
• Gene: CG31445 / 326140
• FlyBaseID: FBgn0051445
• Length: 927
• Species: Drosophila melanogaster
• Sequence 2: NP_001335117.1
• Gene: rnpepl1 / 100535895
• ZFINID: ZDB-GENE-030131-5522
• Length: 692
• Species: Danio rerio
• Alignment Length: 787
• Identity: 164/787 - (20%)
• Similarity: 262/787 - (33%)
• Gaps: 258/787 - (32%)

  Fly    70 NITLHSKNLTIDESRITLRQISGAGNMDNCVSSTSVNP--------THDYYIFHT--CKELLAGN 124
            ::.||   |.....|||..|:         :..|.|.|        ||...:.|:  ||...|..
Zfish    52 HLDLH---LNFAVKRITGWQV---------LELTPVQPGVQSLILDTHPSLLIHSVDCKVPGASG 104

  Fly   125 VYKLFLPFSADLTPQLFGYYRSS---------------YKDPVTNKTR------WLSA------- 161
            ...:||..:..:.|  |..|.||               ::..|...|.      ||.|
Zfish   105 APDVFLSLTYRVEP--FTDYGSSLNITLPAAVIRPHRAFRVTVRYTTTDGPAIWWLDAELTCGQT 167

  Fly   162 -----TQFEPSSARKAFPCFDEPGFKASFVVTLGYHKQFNALSNMPVREIRPHESLANYIWCEFQ 221
                 ||......|..|||||.|..|:::..|:...:....|.:..    |...|..:.:: :|.
Zfish   168 RPLVFTQGHSVCNRSFFPCFDTPAVKSTYSATVRVPEGVTVLMSAS----RSAYSKQDRVF-QFS 227

  Fly   222 ESVPMSTYLVAYSVNDFSFKPSTLPNGALFRTWARP-----------NAIDQCDYAAE--FGPKV 273
            ...|:..||||....|......    |...|.||.|           .::::....||  |||.|
Zfish   228 MEYPVPAYLVALVAGDLQHADI----GPRSRVWAEPCILTCAVSKLGGSVERWLNVAEGLFGPYV 288

  Fly   274 LQYYEEFFGIRYPLPKIDQMAVPDFSAGAMENWGLVKYRESTLLYSPTHSSLADKQD--LANVIA 336
            ...|:..|     ||       |.|...||||..|      |.:.    ||:.:.|:  |.:||
Zfish   289 WGRYDLVF-----LP-------PSFPIVAMENPCL------TFII----SSILESQEFLLIDVI- 330

  Fly   337 HELAHQWFGNLVTMKWWTDLWLNEGFATYVAGLGVQEIYPEWHSRDKGSLTALMTAFRLDSLVSS 401
            ||:||.||||.||...|.::||:||.|||.......|.|.|       :.|.|.|.||||:|...
Zfish   331 HEIAHGWFGNAVTNATWEEMWLSEGLATYAQRRITTEAYGE-------AFTCLETVFRLDALHRQ 388

  Fly   402 HPISRPIQMVTEIEESFD----------AISYQKGSAVLRMMHLFMGE-ESFRTGLREYLKLYAY 455
            ..:......|::::..|:          ..:|:||...:..:....|: :.|.:.||.|::.:.:
Zfish   389 MRLLGDNNPVSKLQAKFEPGVNPSSLMNLFTYEKGFCFVSYLSQLCGDIKRFDSFLRAYIEKFRF 453

  Fly   456 KNAEQNNLWESLT---------TAAHQNGALPGHYDINTIMDSWTLQTGFPVLNITRDYSTGTAE 511
            .:....:|.:...         ..|.:.|         ...:.|....|.|:..  .|.|.|
Zfish   454 SSVIAQDLLDFFLGFFPELKEGCVAQREG---------LEFERWLNGCGPPLCE--PDLSAG--- 504

  Fly   512 ITQERYLRNSQIPQADRVGCWWVPLSYTTQDENDFNNTSPKAWMECSSTDEGVPTTIDHSAGPEE 576
                   |....|.......|              .|.:|
Zfish   505 -------RTLTGPVQHLCDLW--------------GNDAP------------------------- 523

  Fly   577 WLILNIQLSTPYKANYDARNWKLLIDTLNSKDFQSI----HVINRAQLIDDVL------YFAWTG 631
                    .|...:.:|..:|         ..||::    .:::|:.|..:|:      |.|...
Zfish   524 --------DTQVISTFDLSSW---------STFQTVLFLDRLLDRSPLSQEVMSLLSSCYAALLD 571

  Fly   632 EQDYETALQVTNYLRRERDLIPWKSALDNLKLLNRILRQTPNFGSF-KRYMQKLLT-PIYEHL-H 693
            :.:.|..::             |.    .:.:.|......|...|| .::..::.| |:||.| .
Zfish   572 DMNAEVQIR-------------WL----QIVVRNSFYPDLPRVRSFLHKHTSRMYTVPLYEDLCG 619

  Fly   694 GMNDTFSL----MTQQ----------DEVLLKTTVVNVACQYDVSDCVTQAQAYFRRWRAETNPD 744
            |:...|::    .||.          .::|.:|:.:|.:....:......|.:      :.|:|.
Zfish   620 GVMKCFAVEVFYQTQARLHPNLRRTLQQILFQTSALNTSTAPSLMASAPSAPS------SPTDPP 678

  Fly   745 ENHPVPL 751
            .|..:.|
Zfish   679 PNGTIAL 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31445	NP_651689.1	M1_APN-Q_like	37..492	CDD:341064	121/499 (24%)
		ERAP1_C	577..905	CDD:463368	33/202 (16%)
rnpepl1	NP_001335117.1	M1_LTA4H	36..490	CDD:341062	121/499 (24%)
		Leuk-A4-hydro_C	536..649	CDD:462686	23/138 (17%)