DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31441 and ZNF468

DIOPT Version :9

Sequence 1:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_016882932.1	Gene:	ZNF468 / 90333	HGNCID:	33105	Length:	541	Species:	Homo sapiens

Alignment Length:	299	Identity:	72/299 - (24%)
Similarity:	120/299 - (40%)	Gaps:	92/299 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 KCLEVHKSFMAANRKLLRKKAIVDEELDKPDVEKLQQDLWDHTDQEMCVAMADTAGLL------- 129
            :|::..|||..::  ||:|..|:                  |.:::.|  ..|..|.:
Human   235 ECIQSFKSFNCSS--LLKKHQII------------------HLEEKQC--KCDVCGKVFNQKRYL 277

  Fly   130 ---REDHNDNEKAKDAEDATQNEKNQEEQVQVQTEEVEHCQEQL-HNMSIISKGVSARVPKRTKR 190
               |..|...:..|..|                      |.:.. ||.|:.       :.|....
Human   278 ACHRRCHTGEKPYKCNE----------------------CGKTFGHNSSLF-------IHKALHT 313

  Fly   191 NSKSWFCDQCGGVFKSSTYLKLHLQRHSGHKPFACDICQAKYYTDNEMRRHRILHTDARPYACRF 255
            ..|.:.|::|..||...::|:.|.:.|:|.||:.|.:|...:..::.:.:|.||||..:||.|..
Human   314 GEKPYECEECDKVFSRKSHLERHKRIHTGEKPYKCKVCDEAFAYNSYLAKHTILHTGEKPYTCNE 378

  Fly   256 CSKTYRGCSSKVVHERTHTNERPFQCQHCD----------------------------KAFTSTS 292
            |.|.:...|:...|.|.||.|:|::|:.||                            |.|:..|
Human   379 CGKVFNRLSTLARHHRLHTGEKPYKCEECDKVFSRKSHLERHRRIHSGEKPYKCEECCKVFSRKS 443

  Fly   293 TRQKHEMLHTNQRKYHCEICDQWFLRSSHLTLHQSTKLH 331
            ..::|..:||.::.|.|::||:.|.|.|||..||  ::|
Human   444 NLERHRRIHTGEKPYKCKVCDKAFQRDSHLAQHQ--RVH 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071	4/9 (44%)
		COG5048	<174..337	CDD:227381	53/186 (28%)
		C2H2 Zn finger	197..217	CDD:275370	6/19 (32%)
		C2H2 Zn finger	225..245	CDD:275368	4/19 (21%)
		C2H2 Zn finger	253..273	CDD:275368	6/19 (32%)
		zf-H2C2_2	268..290	CDD:290200	11/49 (22%)
		C2H2 Zn finger	281..301	CDD:275368	7/47 (15%)
		C2H2 Zn finger	309..328	CDD:275368	10/18 (56%)
ZNF468	XP_016882932.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000