DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31441 and AZF1

DIOPT Version :9

Sequence 1:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_014756.3	Gene:	AZF1 / 854280	SGDID:	S000005639	Length:	914	Species:	Saccharomyces cerevisiae

Alignment Length:	243	Identity:	62/243 - (25%)
Similarity:	103/243 - (42%)	Gaps:	38/243 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 PDVEKLQQDLWD-----HTDQEMCVAMADTAGLLREDHNDNEKAKDAEDATQNEKNQEEQVQVQT 160
            ||:..:..|..:     ..||.|.:..|...|.       .||....:|.        :.:..||
Yeast   515 PDISSVSDDATNLIGATKVDQLMLIIQARKKGF-------TEKVNTTQDG--------DLLFNQT 564

  Fly   161 EEVEHCQEQLHNMSIISKGVSARVPKRTK--RNSKSWFCDQCGGVFKSSTYLKLHLQRHSGHKPF 223
            .::      |...|.:..||..  ||.|:  |..|...|..|..:|..:|:|::|::.|.|:|||
Yeast   565 MDI------LPPKSELVGGVEK--PKGTQNTRAVKKHECPYCHRLFSQATHLEVHVRSHIGYKPF 621

  Fly   224 ACDICQAKYYTDNEMRRHRILHTDARPYACRFCSKTYRGCSSKVVHERTHTNERPFQC--QHCDK 286
            .||.|..::.....:|.|..|||..:||:|..|.|.:....:...|..||...:||.|  ::|:|
Yeast   622 VCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTHQKLKPFVCKLENCNK 686

  Fly   287 AFTSTSTRQKHEMLHTNQRKYHCEICDQWFLRSSHLTLHQSTKLHQRR 334
            .||.....:.|      |.::|.|..:....:.:.:...::..|.:|:
Yeast   687 TFTQLGNMKAH------QNRFHKETLNALTAKLAEMNPSENIPLEERQ 728

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071
		COG5048	<174..337	CDD:227381	48/165 (29%)
		C2H2 Zn finger	197..217	CDD:275370	6/19 (32%)
		C2H2 Zn finger	225..245	CDD:275368	5/19 (26%)
		C2H2 Zn finger	253..273	CDD:275368	4/19 (21%)
		zf-H2C2_2	268..290	CDD:290200	9/23 (39%)
		C2H2 Zn finger	281..301	CDD:275368	6/21 (29%)
		C2H2 Zn finger	309..328	CDD:275368	1/18 (6%)
AZF1	NP_014756.3	COG5048	342..768	CDD:227381	62/243 (26%)
		C2H2 Zn finger	595..615	CDD:275368	6/19 (32%)
		C2H2 Zn finger	623..643	CDD:275368	5/19 (26%)
		C2H2 Zn finger	651..671	CDD:275368	4/19 (21%)
		C2H2 Zn finger	679..702	CDD:275368	7/28 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000