DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31441 and CG1792

DIOPT Version :9

Sequence 1:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	359	Identity:	107/359 - (29%)
Similarity:	165/359 - (45%)	Gaps:	50/359 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CRTCGKNVTNLQGRATKLFNKSNYHFISILENITDMYL--EFDTTLPHLICQCCKVQLDRILTFR 70
            |||||..:  .....:.||.:.|...:..:|.:|.::|  .....||..||..|::.|...:.||
  Fly     6 CRTCGLFI--FCSTPSNLFEEPNSVMLHQIEVLTGLFLLGGPGNELPPFICSPCELDLQTAIAFR 68

  Fly    71 NKCLEVHKSFMAA----NRKLLRKKAIVDEELDKPDVEKLQQDLWDHTDQEMCVAMADTAGLLRE 131
            .:.:...|:...:    |.:|:...|:        .|||..|...:.|:.|:       ..||.|
  Fly    69 ERVIRTQKTLQESPNLGNAELIESFAV--------GVEKEIQYAEEVTEIEV-------IDLLPE 118

  Fly   132 DHNDNEKAKDAEDATQNEKNQEEQVQVQTEE-------------------VEHCQEQLHNMSIIS 177
            :|...|..:..|...|||   :.||:|..:|                   .::.|......|.::
  Fly   119 EHLLEETEEPYEICEQNE---QPQVKVPAQEKKLRRSTKTTPTVFTSVKFADNSQATRTQWSRLT 180

  Fly   178 KGVSARVPKRTKRNSKSWFCDQCGGVFKSSTYLKLHLQRHSGHKPFACDICQAKYYTDNEMRRHR 242
            :  ...|..:.:|..:...|:|||..|...:..||||.||:|.|.||||.|..::||...:|||:
  Fly   181 E--DEVVALKRERRKRDCICEQCGRHFTCPSNFKLHLLRHTGVKSFACDQCSQQFYTATLLRRHQ 243

  Fly   243 ILHTDARPYACRFCSKTYRGCSSKVVHER-THTNERPFQCQHCDKAFTSTSTRQKHEMLHTNQRK 306
            .||.....:.||:|..||...|.::.||| .|||.:||.|:.|:|:|..:...:.|.:.||..|.
  Fly   244 ELHAGNALFQCRYCEATYSNASGRIQHERMRHTNVKPFTCKECNKSFAMSGKLRTHMLSHTGVRA 308

  Fly   307 YHCEICDQWFLRSSHLTLHQSTK--LHQRRAESA 338
            :||:.|...|:|.||||.|..:|  .|...|::|
  Fly   309 FHCDSCQVSFVRRSHLTSHYRSKGHAHTSSAQAA 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071	20/75 (27%)
		COG5048	<174..337	CDD:227381	63/165 (38%)
		C2H2 Zn finger	197..217	CDD:275370	9/19 (47%)
		C2H2 Zn finger	225..245	CDD:275368	8/19 (42%)
		C2H2 Zn finger	253..273	CDD:275368	9/20 (45%)
		zf-H2C2_2	268..290	CDD:290200	12/22 (55%)
		C2H2 Zn finger	281..301	CDD:275368	5/19 (26%)
		C2H2 Zn finger	309..328	CDD:275368	9/18 (50%)
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	20/75 (27%)
		C2H2 Zn finger	198..218	CDD:275368	9/19 (47%)
		C2H2 Zn finger	226..243	CDD:275368	7/16 (44%)
		C2H2 Zn finger	254..275	CDD:275368	9/20 (45%)
		zf-C2H2	281..303	CDD:278523	6/21 (29%)
		C2H2 Zn finger	283..303	CDD:275368	5/19 (26%)
		zf-H2C2_2	296..320	CDD:290200	8/23 (35%)
		C2H2 Zn finger	311..329	CDD:275368	9/17 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950