DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31441 and CG14711

DIOPT Version :9

Sequence 1:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_650094.1	Gene:	CG14711 / 41395	FlyBaseID:	FBgn0037922	Length:	377	Species:	Drosophila melanogaster

Alignment Length:	365	Identity:	92/365 - (25%)
Similarity:	164/365 - (44%)	Gaps:	44/365 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ICRTCGKNVTNLQGRATKLFNKSN---YHFISILENITDMYLEFDTTLPHLICQCCKVQLDRILT 68
            :||.|.....|.:..| .||:.::   ...:..:|.:..:.|.....:|.::|..|..:|.....
  Fly     6 LCRICLTEDINSEAMA-PLFDDNDAQCRELVRKIEEVGSIKLVPLQNIPSMLCYSCVERLTSAHK 69

  Fly    69 FRNKCLEVHKSFMAANRKLLRKKAIVDE--ELDKPDVEKLQQDLWDHTDQEMCVAMADTAG---L 128
            ||..|.|..::|.....|...|....||  .:...::|.:.:...|..|     .:.|..|   :
  Fly    70 FRELCQESERTFATNVVKAEMKSEPTDEVPHVVADNIEYIYESANDFID-----GVEDDIGMENI 129

  Fly   129 LREDHND--NEKAKDAEDATQNEKNQEEQVQVQT------EEVEHCQEQLHNMSIISK------- 178
            :.|...|  .|.::..|.:|..:...|:.:.|..      :.:|.|::.....:.::|
  Fly   130 MEEPLEDGVGETSQAYETSTVVDDLDEDDLLVPNSTDSDYQPIERCRKAKVRKTRMTKRGRGRPR 194

  Fly   179 GVSARVPKRTKR---------------NSKSWFCDQCGGVFKSSTYLKLHLQRHSGHKPFACDIC 228
            |.|:..|:....               :|.:..|:.||.::.....|.:|::||...|||.|:||
  Fly   195 GASSGHPRSFSEERPPVQASFKSSPEVSSTNIMCEICGNIYSKRAALNIHMRRHMAEKPFKCEIC 259

  Fly   229 QAKYYTDNEMRRHRILHTDARPYACRFCSKTYRGCSSKVVHERTHTNERPFQCQHCDKAFTSTST 293
            ...:...:|:.||..:||..:|:.|::|::::...||.:.|||||||||||.|..|.|||:.::.
  Fly   260 SKSFAGPSELNRHIRVHTGEKPFLCKYCNRSFADRSSNIRHERTHTNERPFTCSTCGKAFSYSNV 324

  Fly   294 RQKHEMLHTNQRKYHCEICDQWFLRSSHLTLHQSTKLHQR 333
            .:.|.:.||.::.:.|.:|::.|.|...|..|..|..||:
  Fly   325 LKNHMLTHTGEKPFLCRVCNKTFSRKHQLDQHLGTMTHQQ 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071	18/77 (23%)
		COG5048	<174..337	CDD:227381	56/182 (31%)
		C2H2 Zn finger	197..217	CDD:275370	5/19 (26%)
		C2H2 Zn finger	225..245	CDD:275368	6/19 (32%)
		C2H2 Zn finger	253..273	CDD:275368	7/19 (37%)
		zf-H2C2_2	268..290	CDD:290200	16/21 (76%)
		C2H2 Zn finger	281..301	CDD:275368	6/19 (32%)
		C2H2 Zn finger	309..328	CDD:275368	6/18 (33%)
CG14711	NP_650094.1	zf-AD	6..81	CDD:285071	17/75 (23%)
		C2H2 Zn finger	228..248	CDD:275368	5/19 (26%)
		zf-H2C2_2	240..264	CDD:290200	10/23 (43%)
		COG5048	249..>362	CDD:227381	42/112 (38%)
		C2H2 Zn finger	256..276	CDD:275368	6/19 (32%)
		zf-H2C2_2	268..292	CDD:290200	8/23 (35%)
		C2H2 Zn finger	284..304	CDD:275368	7/19 (37%)
		zf-H2C2_2	299..321	CDD:290200	16/21 (76%)
		C2H2 Zn finger	312..332	CDD:275368	6/19 (32%)
		zf-H2C2_2	325..349	CDD:290200	6/23 (26%)
		C2H2 Zn finger	340..362	CDD:275368	7/21 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24381
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.150