DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31441 and M1BP

DIOPT Version :9

Sequence 1:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_649825.1	Gene:	M1BP / 41042	FlyBaseID:	FBgn0037621	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	409	Identity:	119/409 - (29%)
Similarity:	194/409 - (47%)	Gaps:	87/409 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSELRSICRTCGKNVTNLQGRATKLFNKSNYHFISILENITDMYLEFDTTLPHLICQCCKVQLDR 65
            :..|:|.||.|.|..:|  .|:.|||.:||...|..:|.:|.:.||....||..||:||.::|..
  Fly     6 LKHLKSTCRVCAKYASN--KRSPKLFERSNTKMIDNIEALTGLRLENYGCLPDQICECCSMELAS 68

  Fly    66 ILTFRNKCLEVHKSFMAANRKLL--------------RKKAIVDEEL-------DKPDVEKLQQD 109
            .:..|.:|:       ||.|:||              .:.|::.|::       |..:|....|:
  Fly    69 AVKLRERCI-------AAQRELLLGLTEEQRQGISAFYRAAVMGEDIVQTVKTPDDDEVYATYQE 126

  Fly   110 L---------------WDHTDQEMCVAMA---DTAGLLREDHNDNEKAKDAEDATQNEKNQEEQV 156
            :               :|:|..|:....|   |.|.|:.|...|:..|:|.|.....|.:::.::
  Fly   127 IVLEEPKEEIDDTKVEYDNTYYEVAEGHAGEDDAASLIEEADYDSIMAEDEEQQQTLELDEDTEL 191

  Fly   157 ---------------------QVQTEEVEHCQEQLHNMSIISKGVSARVPKRTKRNSKS------ 194
                                 .|..:|.||       .:|:.|..|  :|.:.|..|..
  Fly   192 IVGDVNDAYVYDSDDEVAVLDNVLDDEYEH-------ENIVVKKCS--LPPKPKVRSDDARRRGT 247

  Fly   195 ---WFCDQCGGVFKSSTYLKLHLQRHSGHKPFACDICQAKYYTDNEMRRHRILHTDARPYACRFC 256
               :.|:|||...|.....:||.:||.|.|.|.|::||:::.|.:|::||...||..||:||::|
  Fly   248 GGVYICEQCGNHIKGRMAFELHCRRHRGDKQFGCELCQSRFCTTSELKRHMRKHTGERPFACKYC 312

  Fly   257 SKTYRGCSSKVVHERTHTNERPFQCQHCDKAFTSTSTRQKHEMLHTNQRKYHCEICDQWFLRSSH 321
            .:.:...:::|.||||||||||:.|..|.||||:....:.|.::|:.:|.|.||:||:.|:..:|
  Fly   313 GRCFTDYTTRVKHERTHTNERPYVCGTCGKAFTTGYILKNHMLIHSGERAYRCELCDKSFMLPTH 377

  Fly   322 LTLHQSTKLHQRRAESARI 340
            |:.|..:.:|:|..|.|.:
  Fly   378 LSTHFRSGVHKRHLEKAEM 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071	25/74 (34%)
		COG5048	<174..337	CDD:227381	63/171 (37%)
		C2H2 Zn finger	197..217	CDD:275370	7/19 (37%)
		C2H2 Zn finger	225..245	CDD:275368	7/19 (37%)
		C2H2 Zn finger	253..273	CDD:275368	6/19 (32%)
		zf-H2C2_2	268..290	CDD:290200	15/21 (71%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		C2H2 Zn finger	309..328	CDD:275368	8/18 (44%)
M1BP	NP_649825.1	zf-AD	13..84	CDD:214871	28/79 (35%)
		C2H2 Zn finger	253..273	CDD:275368	7/19 (37%)
		COG5048	276..>331	CDD:227381	22/54 (41%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		zf-H2C2_2	293..317	CDD:290200	10/23 (43%)
		C2H2 Zn finger	309..329	CDD:275368	6/19 (32%)
		zf-H2C2_2	324..346	CDD:290200	15/21 (71%)
		C2H2 Zn finger	337..357	CDD:275368	7/19 (37%)
		zf-H2C2_2	350..372	CDD:290200	8/21 (38%)
		C2H2 Zn finger	365..383	CDD:275368	8/17 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	1	0.900	-	-		E33208_3CBI2
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850