DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31441 and CG8159

DIOPT Version :9

Sequence 1:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	368	Identity:	97/368 - (26%)
Similarity:	172/368 - (46%)	Gaps:	67/368 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LRSICRTCGKNVTNLQGRATKLFNKSNYHFISILENITDMYLEFDTTLPHLICQCCKVQLDRILT 68
            |:::||.|..:..|  .::.||||......:..:..:|.:.|:.:..||..:|:.|:..|...::
  Fly     2 LQNVCRVCASSTDN--SKSLKLFNSGACKVLQQINLLTGVLLQCEPGLPDWMCETCQTDLKSAIS 64

  Fly    69 FRNKCLEVHKSFMAANRKLLRKKAIVDEELDKPDVEKLQQDLWDHTDQEMCVAMADTAGLLREDH 133
            ||::||...|.|   ...|:|.    :|:..:..|.:                   :|...|:.|
  Fly    65 FRDRCLRSQKIF---EESLVRN----EEDTFRSSVRR-------------------SARSQRQRH 103

  Fly   134 NDNEKAKDAE--------DATQNEKNQEEQVQVQTEEVEHCQEQLHNMSIISKGVSARVP----- 185
            .|......|.        ::..|...:::.:    :.::.|.|.  :|.:..|.:|:...
  Fly   104 EDTAPKTPASPLEVMIKLESLSNGDEEDDGI----DHLDSCNEA--DMELAIKAMSSSTEDDGTT 162

  Fly   186 -----KRTKRNSKS---------------WFCDQCGGVFKSSTYLKLHLQRHSGHKPFACDICQA 230
                 |||:|....               :||||||......:....||::|||.:||.|::|.|
  Fly   163 SPVRLKRTRRRGLKKGGKGENRTKVTLPVFFCDQCGNNITGKSSFDRHLRKHSGIRPFQCELCPA 227

  Fly   231 KYYTDNEMRRHRILHTDARPYACRFCSKTYRGCSSKVVHERTHTNERPFQCQHCDKAFTSTSTRQ 295
            ::.:..|::.|:::||..|.:.||:|.:||...|.::.|||||||:|||.|..|.|:||::...:
  Fly   228 RFLSSGELKGHQVMHTGDRKFQCRYCDRTYVNYSGRLRHERTHTNDRPFICAQCGKSFTNSYILK 292

  Fly   296 KHEMLHTNQRKYHCEICDQWFLRSSHLTLHQSTKLHQRRAESA 338
            .|.::||.:|.:.||:|.:.|.|.:||..|..:..|:...|.:
  Fly   293 NHMLIHTGERLFRCELCHRSFARPTHLKTHFRSNTHKHNLEKS 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071	21/74 (28%)
		COG5048	<174..337	CDD:227381	61/187 (33%)
		C2H2 Zn finger	197..217	CDD:275370	7/19 (37%)
		C2H2 Zn finger	225..245	CDD:275368	5/19 (26%)
		C2H2 Zn finger	253..273	CDD:275368	9/19 (47%)
		zf-H2C2_2	268..290	CDD:290200	14/21 (67%)
		C2H2 Zn finger	281..301	CDD:275368	6/19 (32%)
		C2H2 Zn finger	309..328	CDD:275368	8/18 (44%)
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	21/77 (27%)
		C2H2 Zn finger	194..214	CDD:275368	7/19 (37%)
		COG5048	<197..322	CDD:227381	49/124 (40%)
		zf-H2C2_2	206..231	CDD:290200	10/24 (42%)
		C2H2 Zn finger	222..242	CDD:275368	5/19 (26%)
		C2H2 Zn finger	250..270	CDD:275368	9/19 (47%)
		zf-H2C2_2	265..287	CDD:290200	14/21 (67%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		zf-H2C2_2	291..315	CDD:290200	8/23 (35%)
		C2H2 Zn finger	306..328	CDD:275368	8/21 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950