DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31441 and nom

DIOPT Version :9

Sequence 1:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001262384.1	Gene:	nom / 41038	FlyBaseID:	FBgn0037617	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	352	Identity:	94/352 - (26%)
Similarity:	156/352 - (44%)	Gaps:	46/352 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LRSICRTCGKNVTNLQGRATKLFNKSNYHFISILENITDMYLEFDTTLPHLICQCCKVQLDRILT 68
            |.::||.||:  :.|..:|.:||.......:..::.||.:.|:.....|.::|.||:..|...:.
  Fly     2 LINVCRVCGR--SRLCPKAVELFKPGRQDILRRIQLITGILLQQIPNAPDMVCFCCQTDLQSAMI 64

  Fly    69 FRNKCLEVHKSFM---------AANRKLLR------KKAIVDEELDKPDVEKLQQDLWD--HTDQ 116
            ||.:|:...|.::         |:..|.:.      ||........:|   ::..::.|  .|::
  Fly    65 FRRQCILQQKKWVPLLQSDKVGASEEKKVEPNDPSTKKKTTKRRRGRP---RMPLEIVDIVVTNE 126

  Fly   117 EMCVAMADTAGLLREDHNDNEKAKDAEDATQNEKNQEEQVQVQTEEVEHCQEQLHNMSIISKGVS 181
            ....|.....|   ::.:...:..:..|||.::.|.|| :.:..|:.......|.|:.|..
  Fly   127 SKASAGESVGG---DEFDQPVEISNEPDATDSDVNLEE-IDLPDEDGLESDHDLPNVQIHK---- 183

  Fly   182 ARVPKRTKRNSKSWFCDQCGGVFKSSTYLKLHLQRHSGHKPFACDICQAKYYTDNEMRRHRIL-H 245
                           ||.||.:..:.:.|..|...|:|.:|:.|..|...:...:|::.|.:. |
  Fly   184 ---------------CDTCGIIKNNKSSLVRHQFEHNGIRPYPCKECPKTFLVASELKAHNLTHH 233

  Fly   246 TDARPYACRFCSKTYRGCSSKVVHERTHTNERPFQCQHCDKAFTSTSTRQKHEMLHTNQRKYHCE 310
            |...|:|||:|.:.|.....:..|||.|||||||.|..|.||||.|...:.|..:|...|||.|:
  Fly   234 TLEPPFACRYCDRRYFSVVGRKKHERVHTNERPFVCDQCGKAFTRTCILKAHMAVHQVVRKYSCD 298

  Fly   311 ICDQWFLRSSHLTLHQSTKLHQRRAES 337
            :||:.|....||..|..:..|:|.||:
  Fly   299 VCDRSFSLKKHLATHFISNTHKRNAEA 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071	20/83 (24%)
		COG5048	<174..337	CDD:227381	54/163 (33%)
		C2H2 Zn finger	197..217	CDD:275370	6/19 (32%)
		C2H2 Zn finger	225..245	CDD:275368	4/20 (20%)
		C2H2 Zn finger	253..273	CDD:275368	7/19 (37%)
		zf-H2C2_2	268..290	CDD:290200	15/21 (71%)
		C2H2 Zn finger	281..301	CDD:275368	8/19 (42%)
		C2H2 Zn finger	309..328	CDD:275368	7/18 (39%)
nom	NP_001262384.1	zf-AD	5..76	CDD:214871	20/72 (28%)
		C2H2 Zn finger	184..204	CDD:275368	6/19 (32%)
		C2H2 Zn finger	212..261	CDD:275368	15/48 (31%)
		zf-H2C2_2	255..278	CDD:290200	15/22 (68%)
		C2H2 Zn finger	269..289	CDD:275368	8/19 (42%)
		zf-H2C2_2	282..305	CDD:290200	8/22 (36%)
		C2H2 Zn finger	297..313	CDD:275368	6/15 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950