DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31441 and CG17359

DIOPT Version :9

Sequence 1:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster

Alignment Length:	369	Identity:	85/369 - (23%)
Similarity:	147/369 - (39%)	Gaps:	78/369 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ELRSICRTCGKNVTNLQGRATKLFNKSNY------HFISILENITDMYLEFDTTLPHLICQCCKV 61
            ::..:||.|......|....|:.:..||.      ...::|...:...:..:..:|..||..|..
  Fly     2 DISQMCRVCRDESDCLLDIYTEPYASSNRVQEQEPVLATMLRECSGCSVHKEDGMPQFICVECAE 66

  Fly    62 QLDRILTFRNKCLEVHKSFMAANRKLLRKKAIVDEELDKPDVEKLQQDLWDHTDQEMCVAMADTA 126
            .:......|.:|.:.|:.|     :.||   ::.:|||  |:|.. .::.|:.:.:|.|::.: |
  Fly    67 AVRNAYRLRRQCRKSHQYF-----EQLR---LMMKELD--DIEYC-LNIGDNIEPQMPVSVME-A 119

  Fly   127 G--------LLRE-------------------DHNDNEKAKDAEDATQNEKNQEEQVQVQTE--- 161
            |        ||.|                   |:|:::.|:....|.......:.:.:..::
  Fly   120 GKTPETSEPLLVELVQVKYMPPEPKPISSPLPDNNEHKLAQSYSPAKTPHNKSKRRARSYSDNDS 184

  Fly   162 -----EVEH-CQEQLHNMSIISKGVSARVPKRTKRNSKSWFCDQCGGVFKSSTYLKLHLQRHSGH 220
                 |:|| ..:::.|.|  .:|...|||       ..:.|..|...|.....|::|::.|:|.
  Fly   185 WSPDSELEHEDDDKIWNAS--KRGKPKRVP-------GPYRCKLCTQSFTQKQNLEIHMRIHTGE 240

  Fly   221 KPFACDICQAKYYTDNEMRRHRILHTDARPYACRFCSKTYRGCSSKVVHERTHTNERPFQCQHCD 285
            :|:.|.:|...:.....::.|...||..||:.|..|.|.:|......||.||||.|:||:|..|.
  Fly   241 RPYKCSLCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVHTRTHTGEQPFKCSKCQ 305

  Fly   286 KAFTSTSTRQKHEMLHTNQRKYHCEICDQWFLRSSHLTLHQSTK 329
            ::|...:..|||...||               |....|..|.||
  Fly   306 QSFKQLNGLQKHMSAHT---------------RGKRRTSSQETK 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071	16/80 (20%)
		COG5048	<174..337	CDD:227381	46/156 (29%)
		C2H2 Zn finger	197..217	CDD:275370	5/19 (26%)
		C2H2 Zn finger	225..245	CDD:275368	3/19 (16%)
		C2H2 Zn finger	253..273	CDD:275368	7/19 (37%)
		zf-H2C2_2	268..290	CDD:290200	12/21 (57%)
		C2H2 Zn finger	281..301	CDD:275368	6/19 (32%)
		C2H2 Zn finger	309..328	CDD:275368	3/18 (17%)
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	16/86 (19%)
		zf-C2H2	215..237	CDD:278523	5/21 (24%)
		C2H2 Zn finger	217..237	CDD:275368	5/19 (26%)
		zf-H2C2_2	229..254	CDD:290200	7/24 (29%)
		C2H2 Zn finger	245..265	CDD:275368	3/19 (16%)
		zf-H2C2_2	257..282	CDD:290200	8/24 (33%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	12/23 (52%)
		C2H2 Zn finger	301..321	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457837
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930