DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31441 and Zfp819

DIOPT Version :9

Sequence 1:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001014039.1	Gene:	Zfp819 / 308561	RGDID:	1309564	Length:	614	Species:	Rattus norvegicus

Alignment Length:	232	Identity:	64/232 - (27%)
Similarity:	107/232 - (46%)	Gaps:	33/232 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 GLLRED----HNDNEKAKDAEDATQNEKNQEEQVQVQTEEVEH---------------------- 165
            |:|.:|    :..:|||..|..|: .|:.....:.::|..:.|
  Rat   268 GILSQDEPVEYTKDEKAFTAGSAS-CEQQTTNTLDLETHFICHICGKSFLQKSELSFHPGTSREE 331

  Fly   166 ----CQEQLHNMSIISKGVSARVPKRTKRNSKSWFCDQCGGVFKSSTYLKLHLQRHSGHKPFACD 226
                |.:.|.:::.....:.|.....||:  |.:.|..||..|..:::||:||:.|:|.:|:.|.
  Rat   332 TRYECPDCLKSLTTSPSSLQAHHEAHTKQ--KPYTCHDCGKSFSYASHLKVHLRIHTGERPYVCS 394

  Fly   227 ICQAKYYTDNEMRRHRILHTDARPYACRFCSKTYRGCSSKVVHERTHTNERPFQCQHCDKAFTST 291
            .|...:...:.:..|:.:||..:||||..|.|.:...|....|.|.||.|:|::|:.|.|.|::.
  Rat   395 DCGKAFSQKSVLTTHQRIHTGEKPYACSHCGKLFVYASDLRKHSRFHTGEKPYECRDCGKVFSNK 459

  Fly   292 STRQKHEMLHTNQRKYHCEICDQWFLRSSHLTLHQST 328
            |....|..:||.::.|.|..|.:.|.|.|||.:|..|
  Rat   460 SHLPVHRRIHTGEKPYKCRDCGKSFRRKSHLQVHGRT 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071
		COG5048	<174..337	CDD:227381	51/155 (33%)
		C2H2 Zn finger	197..217	CDD:275370	8/19 (42%)
		C2H2 Zn finger	225..245	CDD:275368	3/19 (16%)
		C2H2 Zn finger	253..273	CDD:275368	6/19 (32%)
		zf-H2C2_2	268..290	CDD:290200	10/21 (48%)
		C2H2 Zn finger	281..301	CDD:275368	6/19 (32%)
		C2H2 Zn finger	309..328	CDD:275368	8/18 (44%)
Zfp819	NP_001014039.1	KRAB	27..81	CDD:214630
		C2H2 Zn finger	336..357	CDD:275368	3/20 (15%)
		COG5048	<346..538	CDD:227381	51/153 (33%)
		C2H2 Zn finger	365..385	CDD:275368	8/19 (42%)
		C2H2 Zn finger	393..413	CDD:275368	3/19 (16%)
		C2H2 Zn finger	421..441	CDD:275368	6/19 (32%)
		C2H2 Zn finger	449..469	CDD:275368	6/19 (32%)
		C2H2 Zn finger	477..497	CDD:275368	9/20 (45%)
		SFP1	<499..582	CDD:227516
		C2H2 Zn finger	505..525	CDD:275368
		C2H2 Zn finger	533..553	CDD:275368
		C2H2 Zn finger	561..581	CDD:275368
		zf-H2C2_2	573..598	CDD:404364
		C2H2 Zn finger	589..609	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000