DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31441 and ZNF558

DIOPT Version :9

Sequence 1:NP_731558.1 Gene:CG31441 / 326139 FlyBaseID:FBgn0051441 Length:341 Species:Drosophila melanogaster
Sequence 2:NP_653294.1 Gene:ZNF558 / 148156 HGNCID:26422 Length:402 Species:Homo sapiens


Alignment Length:357 Identity:86/357 - (24%)
Similarity:140/357 - (39%) Gaps:91/357 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 DMYLEFDTTLPHLICQCCKVQLDRILTFRNKCLEVHKSFMAANRKLLRKKAIVDEELDKPDVEKL 106
            |:.||....|..|.|:..|..|       ...||..|..:...|.:|....        ||:|.|
Human    70 DVMLENCRNLASLGCRVNKPSL-------ISQLEQDKKVVTEERGILPSTC--------PDLETL 119

  Fly   107 QQDLWDHTDQEMCVAMADTAGLLREDHNDNEKAKDAED-----ATQNEKNQEEQVQVQTEEVEHC 166
            .:..| .|.::.......:.|:..|..:...|..:...     :|::...|.:::        |.
Human   120 LKAKW-LTPKKNVFRKEQSKGVKTERSHRGVKLNECNQCFKVFSTKSNLTQHKRI--------HT 175

  Fly   167 QEQLHNMSIISKGVSAR----VPKRTKRNSKSWFCDQCGGVFKSSTYLKLHLQRHSGHKPFACDI 227
            .|:.::.|...|..|:|    :.||.....|.:.|:.||..|...:.|:|||:.|:|.||:.|:.
Human   176 GEKPYDCSQCGKSFSSRSYLTIHKRIHNGEKPYECNHCGKAFSDPSSLRLHLRIHTGEKPYECNQ 240

  Fly   228 CQAKYYTDNEMRRHR----------------------------ILHTDARPYACRFCSKTYRGCS 264
            |...:.|...::.|:                            .:||..:||.|..|.||:|..|
Human   241 CFHVFRTSCNLKSHKRIHTGENHHECNQCGKAFSTRSSLTGHNSIHTGEKPYECHDCGKTFRKSS 305

  Fly   265 ----------------------------SKVVHERTHTNERPFQCQHCDKAFTSTSTRQKHEMLH 301
                                        |..||:|.||.|:|::|..|.|||.:.|..:||...|
Human   306 YLTQHVRTHTGEKPYECNECGKSFSSSFSLTVHKRIHTGEKPYECSDCGKAFNNLSAVKKHLRTH 370

  Fly   302 TNQRKYHCEICDQWFLRSSHLTLHQSTKLHQR 333
            |.::.|.|..|.:.|..:|:|::|:  ::|.|
Human   371 TGEKPYECNHCGKSFTSNSYLSVHK--RIHNR 400

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31441NP_731558.1 zf-AD 7..82 CDD:285071 11/39 (28%)
COG5048 <174..337 CDD:227381 60/220 (27%)
C2H2 Zn finger 197..217 CDD:275370 8/19 (42%)
C2H2 Zn finger 225..245 CDD:275368 4/47 (9%)
C2H2 Zn finger 253..273 CDD:275368 10/47 (21%)
zf-H2C2_2 268..290 CDD:290200 12/21 (57%)
C2H2 Zn finger 281..301 CDD:275368 8/19 (42%)
C2H2 Zn finger 309..328 CDD:275368 6/18 (33%)
ZNF558NP_653294.1 KRAB 43..100 CDD:214630 10/36 (28%)
C2H2 Zn finger 154..174 CDD:275368 2/27 (7%)
COG5048 <162..398 CDD:227381 62/245 (25%)
C2H2 Zn finger 182..202 CDD:275368 6/19 (32%)
C2H2 Zn finger 210..230 CDD:275368 8/19 (42%)
C2H2 Zn finger 238..258 CDD:275368 4/19 (21%)
C2H2 Zn finger 266..286 CDD:275368 0/19 (0%)
C2H2 Zn finger 294..314 CDD:275368 6/19 (32%)
C2H2 Zn finger 322..342 CDD:275368 4/19 (21%)
C2H2 Zn finger 350..370 CDD:275368 8/19 (42%)
C2H2 Zn finger 378..398 CDD:275368 6/21 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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