DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31441 and ZNF560

DIOPT Version :9

Sequence 1:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_689689.2	Gene:	ZNF560 / 147741	HGNCID:	26484	Length:	790	Species:	Homo sapiens

Alignment Length:	149	Identity:	58/149 - (38%)
Similarity:	79/149 - (53%)	Gaps:	2/149 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 GVSARV--PKRTKRNSKSWFCDQCGGVFKSSTYLKLHLQRHSGHKPFACDICQAKYYTDNEMRRH 241
            |.|:.|  .:|:....|.:.|||||.||.|.:.|..||:.|:|.|||.|..|...:.:...:|.|
Human   470 GTSSGVIEDRRSNTGQKRFDCDQCGKVFVSFSSLFAHLRTHTGEKPFKCYKCGKPFTSSACLRIH 534

  Fly   242 RILHTDARPYACRFCSKTYRGCSSKVVHERTHTNERPFQCQHCDKAFTSTSTRQKHEMLHTNQRK 306
            ...||:.|.|.|:.|.|.:..||....|.|||..|:|::|..|.||||..|...||...|:.::.
Human   535 MRTHTEERLYQCKKCGKAFTKCSYLTKHLRTHAGEKPYECMKCGKAFTERSYLTKHLRRHSGEKP 599

  Fly   307 YHCEICDQWFLRSSHLTLH 325
            |.|:.|.:.|...|.||.|
Human   600 YECKKCGKAFTERSDLTKH 618

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071
		COG5048	<174..337	CDD:227381	58/149 (39%)
		C2H2 Zn finger	197..217	CDD:275370	11/19 (58%)
		C2H2 Zn finger	225..245	CDD:275368	4/19 (21%)
		C2H2 Zn finger	253..273	CDD:275368	7/19 (37%)
		zf-H2C2_2	268..290	CDD:290200	11/21 (52%)
		C2H2 Zn finger	281..301	CDD:275368	9/19 (47%)
		C2H2 Zn finger	309..328	CDD:275368	7/17 (41%)
ZNF560	NP_689689.2	KRAB	13..69	CDD:214630
		KRAB	13..50	CDD:279668
		KRAB	110..161	CDD:214630
		KRAB	110..149	CDD:279668
		C2H2 Zn finger	294..314	CDD:275368
		C2H2 Zn finger	323..342	CDD:275368
		COG5048	344..754	CDD:227381	58/149 (39%)
		C2H2 Zn finger	350..370	CDD:275368
		zf-H2C2_2	362..386	CDD:290200
		C2H2 Zn finger	378..398	CDD:275368
		C2H2 Zn finger	406..426	CDD:275368
		C2H2 Zn finger	434..454	CDD:275368
		C2H2 Zn finger	490..510	CDD:275368	11/19 (58%)
		zf-H2C2_2	502..527	CDD:290200	10/24 (42%)
		C2H2 Zn finger	518..538	CDD:275368	4/19 (21%)
		zf-H2C2_2	531..554	CDD:290200	9/22 (41%)
		C2H2 Zn finger	546..566	CDD:275368	7/19 (37%)
		zf-H2C2_2	558..582	CDD:290200	10/23 (43%)
		C2H2 Zn finger	574..594	CDD:275368	9/19 (47%)
		zf-H2C2_2	586..610	CDD:290200	6/23 (26%)
		zf-C2H2	600..622	CDD:278523	8/19 (42%)
		C2H2 Zn finger	602..622	CDD:275368	7/17 (41%)
		C2H2 Zn finger	630..650	CDD:275368
		C2H2 Zn finger	658..678	CDD:275368
		C2H2 Zn finger	714..734	CDD:275368
		zf-H2C2_2	726..751	CDD:290200
		C2H2 Zn finger	742..762	CDD:275368
		zf-H2C2_2	757..779	CDD:290200
		C2H2 Zn finger	770..790	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000