DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31431 and igcm-4

DIOPT Version :9

Sequence 1:	NP_001247231.1	Gene:	CG31431 / 326138	FlyBaseID:	FBgn0051431	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_508377.1	Gene:	igcm-4 / 180518	WormBaseID:	WBGene00022418	Length:	541	Species:	Caenorhabditis elegans

Alignment Length:	259	Identity:	61/259 - (23%)
Similarity:	103/259 - (39%)	Gaps:	57/259 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 IQQRAGFDVKLQCNLKGLVDESMLNDI-KIHWYFK--QCSENNCHQLGSVDEWTALPCEPSLCRP 102
            |:...|..::|:|..:|       |.: :|.||..  :.||.....:.::   |..|.|.|
Worm   161 IKINTGGKLELRCPAQG-------NPLPEIRWYQNEMEISEKTHKHVSTI---TVEPVESS---- 211

  Fly   103 ELWLRNVTERYSGLYKCSINPHIWDKAQAVDVQL------VRTYQLDVKNTSLAAPEFVDSYPNN 161
                      :||:|:|.:...:...:.|.||.:      ..|...:.:.|::   |.|...|.|
Worm   212 ----------HSGVYRCVVENPLGSLSFAFDVSVGDFFDPTTTEATEYQETAM---EPVIDQPYN 263

  Fly   162 KTTLVGSRVVFQCRVHSEEHPTIKWFRRQTYVGTQSGGEASSAPTT---SNFSNHIVRYNGRTYE 223
            .:...|....|||:|.|.|:..|||.:.            .|.|.:   .:.::.::..||....
Worm   264 ISVYAGHTAQFQCKVKSNENTIIKWLKE------------VSDPLSIRRKDPNSTVIHVNGMNLL 316

  Fly   224 LLSTDPEKMMAPQ-----IYLSKLILDGVRLRDAGHYACVAISYRGHKI-REAFLDVLADVEDT 281
            :|.....:...||     ||.::|.:..|....||.|.||..|.:|..: :.|.|.||:..:.|
Worm   317 VLDHIQTESSLPQEDMDNIYTNRLTIHKVDYHHAGKYICVVTSAQGQIVYKSAELKVLSAYDFT 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31431	NP_001247231.1	IG_like	159..274	CDD:214653	32/123 (26%)
CG31431	NP_001247231.1	Ig	167..275	CDD:299845	30/116 (26%)
igcm-4	NP_508377.1	IGc2	52..114	CDD:197706
		I-set	159..235	CDD:254352	22/97 (23%)
		IGc2	166..225	CDD:197706	18/82 (22%)
		IG_like	261..373	CDD:214653	32/123 (26%)
		Ig	269..374	CDD:299845	30/116 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157495
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19890
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940