DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31431 and Fgfrl1

DIOPT Version :9

Sequence 1:	NP_001247231.1	Gene:	CG31431 / 326138	FlyBaseID:	FBgn0051431	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_473412.1	Gene:	Fgfrl1 / 116701	MGIID:	2150920	Length:	529	Species:	Mus musculus

Alignment Length:	335	Identity:	80/335 - (23%)
Similarity:	128/335 - (38%)	Gaps:	86/335 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LIQQRAGFDVKLQCNLKG--------LVDESMLNDIKIHWYFKQCSENNCHQLGSVDEWTALPCE 96
            :|.:..|..|:|:|...|        :.|:..|..::...:.|:             :||
Mouse   155 VIARPVGSSVRLKCVASGHPRPDIMWMKDDQTLTHLEASEHRKK-------------KWT----- 201

  Fly    97 PSLCRPELWLRNVTERYSGLYKCSINPHIWDKAQAVDVQLVRTYQLDVKNTSLAAPEFVDSYPNN 161
                   |.|:|:....||.|.|.::    :||.|::.    ||::||...:.:.|....::|.|
Mouse   202 -------LSLKNLKPEDSGKYTCRVS----NKAGAINA----TYKVDVIQRTRSKPVLTGTHPVN 251

  Fly   162 KTTLVGSRVVFQCRVHSEEHPTIKWFRRQTYVGTQSGGEASSAPTTSNFSNHIVRYNGRTYELLS 226
            .|...|....|||:|.|:..|.|:|.:|..|     |.|..        .|..:...|:.:.:|.
Mouse   252 TTVDFGGTTSFQCKVRSDVKPVIQWLKRVEY-----GSEGR--------HNSTIDVGGQKFVVLP 303

  Fly   227 TDPEKMMAPQIYLSKLILDGVRLRDAGHYACVAISYRGHKIREAFLDVLADVEDTDQENEYWSDY 291
            |..........||:||::...|..|||.|.|:..:..|:..|.|||.||.|
Mouse   304 TGDVWSRPDGSYLNKLLISRARQDDAGMYICLGANTMGYSFRSAFLTVLPD-------------- 354

  Fly   292 GNEDEGVP-----TSDRREFLLLFLMPLGLALLPLTV--WFSYLLYKRCS-------VGH---GD 339
             .:..|.|     :|....:.::..:|.|...:..||  |......|.|:       .||   |.
Mouse   355 -PKPPGPPMASSSSSTSLPWPVVIGIPAGAVFILGTVLLWLCQTKKKPCAPASTLPVPGHRPPGT 418

  Fly   340 CQRIDSDEDL 349
            .:....|:||
Mouse   419 SRERSGDKDL 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31431	NP_001247231.1	IG_like	159..274	CDD:214653	35/114 (31%)
CG31431	NP_001247231.1	Ig	167..275	CDD:299845	32/107 (30%)
Fgfrl1	NP_473412.1	I-set	29..112	CDD:369462
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..151
		Ig2_FGFRL1-like	153..234	CDD:143264	23/111 (21%)
		Ig	257..351	CDD:386229	32/106 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	405..427		4/21 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833323
Domainoid	1	1.000	47	1.000	Domainoid score	I11989
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7169
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19890
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.890