DRSC/TRiP Functional Genomics Resources

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Protein Alignment Npc2e and Npc2

DIOPT Version :9

Sequence 1:NP_731439.2 Gene:Npc2e / 326136 FlyBaseID:FBgn0051410 Length:168 Species:Drosophila melanogaster
Sequence 2:NP_075898.1 Gene:Npc2 / 67963 MGIID:1915213 Length:149 Species:Mus musculus


Alignment Length:153 Identity:39/153 - (25%)
Similarity:70/153 - (45%) Gaps:12/153 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 LRIVVTLALILATVNATNVQ-----QCKNKPFPL-DVNIKDCEEPPCVVYKGTIAVMEVHFLGNN 60
            :|.:....|:||.|.|:..:     .|.:|...: :||:..|...||.::||....:.:.|....
Mouse     1 MRFLAATILLLALVAASQAEPLHFKDCGSKVGVIKEVNVSPCPTDPCQLHKGQSYSVNITFTSGT 65

  Fly    61 NNIKSITATTTAKVLGMNLPYALPDEVSDVCRNLLYGAICPIDKDEDVTYQFNFYVEPSFPEITA 125
            .:..| ||.....:.|:.:|:.:|:  .|.|::   |..|||.||:..:|.....|:..:|.|..
Mouse    66 QSQNS-TALVHGILEGIRVPFPIPE--PDGCKS---GINCPIQKDKVYSYLNKLPVKNEYPSIKL 124

  Fly   126 DVTVTLNDAQNEPITCFVVSCKI 148
            .|...|.|.:...:.|:.:..:|
Mouse   125 VVEWKLEDDKKNNLFCWEIPVQI 147

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Npc2eNP_731439.2 ML 20..144 CDD:294195 32/129 (25%)
Npc2NP_075898.1 Npc2_like 24..145 CDD:238458 32/126 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4063
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11306
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
54.870

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