Protein Alignment Npc2e and NPC2

DIOPT Version :10

• Sequence 1: NP_731439.2
• Gene: Npc2e / 326136
• FlyBaseID: FBgn0051410
• Length: 168
• Species: Drosophila melanogaster
• Sequence 2: NP_001350617.1
• Gene: NPC2 / 10577
• HGNCID: 14537
• Length: 174
• Species: Homo sapiens
• Alignment Length: 166
• Identity: 43/166 - (25%)
• Similarity: 74/166 - (44%)
• Gaps: 14/166 - (8%)

  Fly     2 LRIVVTLALILATVNATNVQQCKNKP------FPLDVNIKDCEEPPCVVYKGTIAVMEVHFLGNN 60
            :|.:....|:||...|...:..:.|.      ...:||:..|...||.:.||....:.|.|..|.
Human     1 MRFLAATFLLLALSTAAQAEPVQFKDCGSVDGVIKEVNVSPCPTQPCQLSKGQSYSVNVTFTSNI 65

  Fly    61 NNIKSITATTTAKVLGMNLPYALPDEVSDVCRNLLYGAICPIDKDEDVTYQFNFYVEPSFPEITA 125
            .: ||..|.....::|:.:|:.:|:  .|.|::   |..|||.||:..:|.....|:..:|.|..
Human    66 QS-KSSKAVVHGILMGVPVPFPIPE--PDGCKS---GINCPIQKDKTYSYLNKLPVKSEYPSIKL 124

  Fly   126 DVTVTLNDAQNEPITCFVVSCKI--RKGATAAQMDG 159
            .|...|.|.:|:.:.|:.:..:|  ..|...|.::|
Human   125 VVEWQLQDDKNQSLFCWEIPVQIVSLSGGERAWVEG 160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Npc2e	NP_731439.2	ML	20..144	CDD:469700	34/129 (26%)
NPC2	NP_001350617.1	Npc2_like	24..145	CDD:238458	34/126 (27%)