Protein Alignment CG31343 and AAP1

DIOPT Version :10

• Sequence 1: NP_732652.1
• Gene: CG31343 / 326133
• FlyBaseID: FBgn0051343
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_011913.1
• Gene: AAP1 / 856443
• SGDID: S000001089
• Length: 856
• Species: Saccharomyces cerevisiae
• Alignment Length: 905
• Identity: 249/905 - (27%)
• Similarity: 410/905 - (45%)
• Gaps: 90/905 - (9%)

  Fly    58 LPNTTEPESYNVELWTNVHNGDTEFNGTVNIDIRVLNETSN-ITLHYRQTSNFEATIISRDVATP 121
            |||...|..|::.|..|..  ...|.|::.||:::.:.:.| :.::|     .|....|..:...
Yeast     6 LPNNVTPLHYDITLEPNFR--AFTFEGSLKIDLQINDHSINSVQINY-----LEIDFHSARIEGV 63

  Fly   122 TAIPLTVTPELQREFLVLTQTTAGEAFGANTNWTITINYTGIHRSDMGGFYISSYTDD-DGEQHF 185
            .||.:......|:..||....|. |..|.:..  :.|.::||....|.|||.:.|||. .||..:
Yeast    64 NAIEVNKNENQQKATLVFPNGTF-ENLGPSAK--LEIIFSGILNDQMAGFYRAKYTDKVTGETKY 125

  Fly   186 LATTQFESTNARHAFPCYDEPARRANFTITIHHDPSYTAISNMPVNTAATSSG--VTAFQTTPKM 248
            :||||.|:|:||.||||:|||..:|.|.:|:..:...|.:|||.|.......|  .|.|.|||||
Yeast   126 MATTQMEATDARRAFPCFDEPNLKATFAVTLVSESFLTHLSNMDVRNETIKEGKKYTTFNTTPKM 190

  Fly   249 STYLVAFIVSDFESTTGELNGIRQRVFSRKGKQDQQEWALWSGLLVESSLASY---FGVPFALPK 310
            |||||||||:|..........|..||:|..|   .:::..::..|...:|..:   |.:.:.|||
Yeast   191 STYLVAFIVADLRYVESNNFRIPVRVYSTPG---DEKFGQFAANLAARTLRFFEDTFNIEYPLPK 252

  Fly   311 LDQAGIPDFSAGAMENWGLATYREQYMWWNKQNSTINLKTNIANIIGHEYAHMWFGDLVSIKWWT 375
            :|...:.:|||||||||||.|||...:..:.:||:::....:|.:|.||.||.|||:||::.||.
Yeast   253 MDMVAVHEFSAGAMENWGLVTYRVIDLLLDIENSSLDRIQRVAEVIQHELAHQWFGNLVTMDWWE 317

  Fly   376 YLWLKEGFATLFSYESNDIAFPLWDTYQIFHVNDYNSALLNDALASAVPMTHYVQTPSEISNRYN 440
            .|||.|||||..|:.|.:...|.|..::.:..::...||..|:|.|:.|:...|....||:..::
Yeast   318 GLWLNEGFATWMSWYSCNKFQPEWKVWEQYVTDNLQRALNLDSLRSSHPIEVPVNNADEINQIFD 382

  Fly   441 TFSYAKPASVLYMFKNAWTDKVFRTGLNKYLTKNQYTSC---DEWDLFASFQESADELGFTLPAS 502
            ..||:|.:|:|.|......::.|..|:::||.|.:|.:.   |.||..      ||..|    ..
Yeast   383 AISYSKGSSLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTGDLWDAL------ADASG----KD 437

  Fly   503 VDDIFSSWSHQAGYPLLTVTRNYNAGTITITQKRY-----VANKTDTNSATWYVPLNFATA--NK 560
            |..:.:.|:.:.|:|:|:|..:.|  .||:||.||     |..:.||......:.|..:|.  |.
Yeast   438 VCSVMNIWTKRVGFPVLSVKEHKN--KITLTQHRYLSTGDVKEEEDTTIYPILLALKDSTGIDNT 500

  Fly   561 YDYRDTSATHYLLNVTETVISDVEASSDDWIIVNIQNSGYYRTLYDTQNYGLITAALKSQPWRFH 625
            ....:.|||..|.|             :::..:|...||.:.|.|..:.:    |.|..|.....
Yeast   501 LVLNEKSATFELKN-------------EEFFKINGDQSGIFITSYSDERW----AKLSKQANLLS 548

  Fly   626 PRNRAQLLYDTYIFVSTDRLSHSILLELLGYLTNEQQYAPW-STANTILTVYDRYLRGDDSYYNF 689
            ..:|..|:.|.....::...|.:..|.|:....||..:..| ...|::..:...::...:...|.
Yeast   549 VEDRVGLVADAKALSASGYTSTTNFLNLISNWKNEDSFVVWEQIINSLSALKSTWVFEPEDILNA 613

  Fly   690 QDFVKRLIDPIFDK---IGVNEIPGEHYLNNYLRIVLVSLACQVGSDDCYNQSANKLSEYLYNGT 751
            .|  |..:|.:.:|   :|.|....:.:....|::.|.|.||..|::...:.:.....||. ||.
Yeast   614 LD--KFTLDLVLNKLSELGWNIGEDDSFAIQRLKVTLFSAACTSGNEKMQSIAVEMFEEYA-NGN 675

  Fly   752 --AIEATLKTQAYCAGLRSTTNEIYSRVQSDLLSSSDSTDRSLFISSLGCSGSTSQLLDFLRLSL 814
              ||.|..|...:....|......|.::.:...:...|.::.:.:.:|| .....:||:
Yeast   676 KQAIPALFKAVVFNTVARLGGENNYEKIFNIYQNPVSSEEKIIALRALG-RFEDKELLE------ 733

  Fly   815 DTNNSLSYSERTSLLNSAYSRSEIGLTASLEFLESNW----EAYANLSDSAKPLDAALRGIATY- 874
               .:|||....::||..:.....|:....:.:|..|    |.:..::...:|....|.|:.|.
Yeast   734 ---RTLSYLLDGTVLNQDFYIPMQGIRVHKKGIERLWAWMQEHWDEIAKRLQPGSPVLGGVLTLG 795

  Fly   875 ---VVSEKQKTRLNALVDVVEADGPSYINDDLSTTIDSRITSNFAWLEVNRDPVLNWIED 931
               ..|.:...:::|........|   .:..|:..:|: |.|...|:..:|:.|..::.:
Yeast   796 LTNFTSFEALEKISAFYSRKVTKG---FDQTLAQALDT-IRSKAQWVSRDREIVATYLRE 851

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31343	NP_732652.1	M1_APN-Q_like	65..510	CDD:341064	153/454 (34%)
		ERAP1_C	590..889	CDD:463368	61/312 (20%)
AAP1	NP_011913.1	M1_APN-Q_like	13..447	CDD:341064	154/456 (34%)
		ERAP1_C	517..833	CDD:463368	65/336 (19%)