DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31343 and AT1G63770

DIOPT Version :9

Sequence 1:	NP_732652.1	Gene:	CG31343 / 326133	FlyBaseID:	FBgn0051343	Length:	961	Species:	Drosophila melanogaster
Sequence 2:	NP_001117543.4	Gene:	AT1G63770 / 842681	AraportID:	AT1G63770	Length:	987	Species:	Arabidopsis thaliana

Alignment Length:	967	Identity:	194/967 - (20%)
Similarity:	342/967 - (35%)	Gaps:	260/967 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AVCSLQARLILPLSLDDGQLETKG-AALFATSRVDDNSAGNYR-------LPNTTEPESY--NVE 70
            |:| |:....||.|:|..:..::. ....||..|.|.:..:..       |.|.|:|:.|  .|:
plant    52 AIC-LRKNRFLPHSVDTHKQNSRRLICSVATESVPDKAEDSKMDAPKEIFLKNYTKPDYYFETVD 115

  Fly    71 LWTNVHNGDTEFNGTVNIDIRVLNETSNITLHYRQTSNFEATIISRDVATPTAIPLTVTPELQRE 135
            |..::....|..:..:.:..||...::.:.|     ...:..::|          :.|..:|.:|
plant   116 LSFSLGEEKTIVSSKIKVSPRVKGSSAALVL-----DGHDLKLLS----------VKVEGKLLKE 165

  Fly   136 --------FLVLTQTTAGEAFGANTNWTI----TINYTGIHRSDMGGFYISSYTDDDGEQHFLAT 188
                    .|.|....|.|:|....:..|    ..:..|:::|. |.|                .
plant   166 GDYQLDSRHLTLPSLPAEESFVLEIDTEIYPHKNTSLEGLYKSS-GNF----------------C 213

  Fly   189 TQFESTNARHAFPCYDEPARRANFTITIHHDPSY--TAISNMPVNTAATSSG---VTAFQTTPKM 248
            ||.|:...|......|.|...|.:|..:..|.:.  ..:||..:.:.....|   ...::...|.
plant   214 TQCEAEGFRKITFYQDRPDIMAKYTCRVEGDKTLYPVLLSNGNLISQGDIEGGRHYALWEDPFKK 278

  Fly   249 STYLVAFIVSDFESTTGELNGIRQRVF-SRKGKQDQQEWALWSGL--LVESSLASY--------- 301
            ..||.|.:.....|        |...| :|.|:|...:  :|:..  |.:::.|.|
plant   279 PCYLFALVAGQLVS--------RDDTFTTRSGRQVSLK--IWTPAEDLPKTAHAMYSLKAAMKWD 333

  Fly   302 ---FGVPFALPKLDQAGIPDFSAGAMENWGLATYREQYMWWNKQNSTINLKTNIANIIGHEYAHM 363
               ||:.:.|...:...:|||:.|||||..|..:..:.:..:.:.:|......|..:|||||.|.
plant   334 EDVFGLEYDLDLFNIVAVPDFNMGAMENKSLNIFNSKLVLASPETATDADYAAILGVIGHEYFHN 398

  Fly   364 WFGDLVSIKWWTYLWLKEGFATLFSYE-SNDIAFPLWDTYQIFHVNDYNSALLNDALASAVPMTH 427
            |.|:.|:.:.|..|.||||.......| |:|:.     :..:..:.|.:...:......|.||.|
plant   399 WTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDMG-----SRTVKRIADVSKLRIYQFPQDAGPMAH 458

  Fly   428 YVQTPS--EISNRYNTFSYAK------------PASVLYMFKNAWTDKVFRTGLNKYLTKN--QY 476
            .|:..|  ::.|.|....|.|            .|.|:.|:|.....:.||.|::.|..::  |.
plant   459 PVRPHSYIKMDNFYTVTVYEKVWLFTNSVLLYAGAEVVRMYKTLLGTQGFRKGIDLYFERHDEQA 523

  Fly   477 TSCDEWDLFASFQESADELGFTLPASVDDIFSSWSHQAGYPLLTVTRNYNAGTITITQK---RYV 538
            .:|:  |.||:.:: |:...|.       .|..|..|||.|::.|..:|||...|.:.|   ...
plant   524 VTCE--DFFAAMRD-ANNADFA-------NFLQWYSQAGTPVVKVVSSYNADARTFSLKFSQEIP 578

  Fly   539 ANKTDTNSATWYVPLNFATANKYDYRDTSATHYLLNVTETVISDVEASSDDWIIVNIQNSGYYRT 603
            ...........::|:                         |:..:::|..|..:.::.:.|..:|
plant   579 PTPGQPTKEPTFIPV-------------------------VVGLLDSSGKDITLSSVHHDGTVQT 618

  Fly   604 LYDTQNYGLITAALKSQPWRFH--PRNRAQLLYDTY---IFVSTDRLSHSILLELLGYLTNEQQY 663
            :..:..  ::....|.:.:.|.  |......|:..:   :.|.|| ||:..|..||.:  :..::
plant   619 ISGSST--ILRVTKKEEEFVFSDIPERPVPSLFRGFSAPVRVETD-LSNDDLFFLLAH--DSDEF 678

  Fly   664 APWSTA-----------------NTILTVYDRYLRG-----DDSYYNFQDFVKRLIDP----IFD 702
            ..|...                 |..|.:..::::|     .||..:.:...|.:..|    |.|
plant   679 NRWEAGQVLARKLMLNLVSDFQQNKPLALNPKFVQGLGSVLSDSSLDKEFIAKAITLPGEGEIMD 743

  Fly   703 KIGVNEIPGEHYLNNYLRIVLVSLACQVGSDDCYNQSANKLSEYLYNGTAIEATLKTQAYCAGLR 767
            .:.|.:....|.:..::|                .|.|::|.|.|..  .:|....|:||
plant   744 MMAVADPDAVHAVRKFVR----------------KQLASELKEELLK--IVENNRSTEAY----- 785

  Fly   768 STTNEIYSRVQSDLLSSSDSTDRSLFISSLGCSGSTSQLLDFLRLSLDTNNSLSYSERTSLLNSA 832
                         :...|:...|:|                       .|.:|:|  ..||.:.|
plant   786 -------------VFDHSNMARRAL-----------------------KNTALAY--LASLEDPA 812

  Fly   833 YSRSEIGLTASLEFLESNWEAYANLSDSAKPLDAALRGIATYVVSEKQKTRLNALVD 889
            |          :|...:.::...||:|..    |||..::    ....|||.:.|.|
plant   813 Y----------MELALNEYKMATNLTDQF----AALAALS----QNPGKTRDDILAD 851

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31343	NP_732652.1	Peptidase_M1	57..446	CDD:279741	93/432 (22%)
		M1_APN_2	65..517	CDD:189008	110/502 (22%)
		ERAP1_C	591..886	CDD:288671	56/325 (17%)
AT1G63770	NP_001117543.4	pepN	92..987	CDD:237585	183/926 (20%)
AT1G63770	NP_001117543.4	M1_APN_1	103..985	CDD:189007	182/915 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X67
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820