DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31343 and APM1

DIOPT Version :9

Sequence 1:	NP_732652.1	Gene:	CG31343 / 326133	FlyBaseID:	FBgn0051343	Length:	961	Species:	Drosophila melanogaster
Sequence 2:	NP_195035.2	Gene:	APM1 / 829446	AraportID:	AT4G33090	Length:	879	Species:	Arabidopsis thaliana

Alignment Length:	944	Identity:	268/944 - (28%)
Similarity:	434/944 - (45%)	Gaps:	113/944 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 DNSAGNYRLPNTTEPESYNVELWTNVHNGD---TEFNGTVNIDIRVLNETSNITLHYRQTSNFEA 111
            |...|..|||....|:.|::.|     |.|   ..|.|||.||:.::.:|..|.|:....|..:|
plant     2 DQFKGEPRLPKFAVPKRYDLRL-----NPDLIACTFTGTVAIDLDIVADTRFIVLNAADLSVNDA 61

  Fly   112 TIISRDVATPTAIPLTVTPEL----QREFLVLTQTTAGEAFGANTNWTITINYTGIHRSDMGGFY 172
            ::   ....|::......|::    :.|.|||   ..||....... .:.:.:.|:....|.|||
plant    62 SV---SFTPPSSSKALAAPKVVLFEEDEILVL---EFGEILPHGVG-VLKLGFNGVLNDKMKGFY 119

  Fly   173 ISSYTDDDGEQHFLATTQFESTNARHAFPCYDEPARRANFTITIHHDPSYTAISNMPVNTAATSS 237
            .|:| :.:||:..:|.||||..:||..|||:||||.:|.|.||:.......|:||||:.....:.
plant   120 RSTY-EHNGEKKNMAVTQFEPADARRCFPCWDEPACKATFKITLEVPTDLVALSNMPIMEEKVNG 183

  Fly   238 G--VTAFQTTPKMSTYLVAFIVSDF---ESTTGELNGIRQRVFSRKGKQDQQEWALWSGLLVESS 297
            .  :.::|.:|.|||||||.:|..|   |..|.:  ||:.||:.:.||.||.::||..|......
plant   184 NLKIVSYQESPIMSTYLVAIVVGLFDYVEDHTSD--GIKVRVYCQVGKADQGKFALHVGAKTLDL 246

  Fly   298 LASYFGVPFALPKLDQAGIPDFSAGAMENWGLATYREQYMWWNKQNSTINLKTNIANIIGHEYAH 362
            ...||.||:.|||:|...||||:||||||:||.||||..:.:::|:|..:.|..:|.::.||.||
plant   247 FKEYFAVPYPLPKMDMIAIPDFAAGAMENYGLVTYRETALLYDEQHSAASNKQRVATVVAHELAH 311

  Fly   363 MWFGDLVSIKWWTYLWLKEGFATLFSYESNDIAFPLWDTYQIFHVNDYNSALLNDALASAVPMTH 427
            .|||:||:::|||:|||.|||||..||.:.|..||.|..:..| :::....|..|.|..:.|:..
plant   312 QWFGNLVTMEWWTHLWLNEGFATWVSYLATDSLFPEWKIWTQF-LDESTEGLRLDGLEESHPIEV 375

  Fly   428 YVQTPSEISNRYNTFSYAKPASVLYMFKNAWTDKVFRTGLNKYLTKNQYTSCDEWDLFASFQESA 492
            .|...:||...::..||.|.|||:.|.::....:||:..|..|:..:.|::....||:|:.:..:
plant   376 EVNHAAEIDEIFDAISYRKGASVIRMLQSYLGAEVFQKSLAAYIKNHAYSNAKTEDLWAALEAGS 440

  Fly   493 DELGFTLPASVDDIFSSWSHQAGYPLLTVTRNYNAGTITITQKRYVANKTDTNSATWYVPL---- 553
            .|       .|:.:.|||:.|.|||:  |:.....|.:.:.|.|::::.: .....|.||:
plant   441 GE-------PVNKLMSSWTKQKGYPV--VSAKIKDGKLELEQSRFLSSGS-PGEGQWIVPVTLCC 495

  Fly   554 -------NFATANK---YDYRDTSATHYLLNVTETVISDVEASSDDWIIVNIQNSGYYRTLYDTQ 608
                   ||...:|   ||.::      ||..:....||....:..||.:|:..:|:||..||..
plant   496 GSYEKRKNFLLESKSGAYDLKE------LLGCSIADGSDKINGTCSWIKINVDQAGFYRVKYDDS 554

  Fly   609 NYGLITAALKSQPWRFHPRNRAQLLYDTYIFVSTDRLSHSILLELLGYLTNEQQYAPWSTANTIL 673
            ....:..|.:||  .....:|..:|.|::......:.|.:.||.|......|..|...|  |.|.
plant   555 LAAGLRNATESQ--SLTSIDRYGILDDSFALTMARQQSLASLLTLCSAYKKELDYTVLS--NLIA 615

  Fly   674 TVYDRYLRGDDSYYNFQDFVKRLIDPIFD----KIGVNEIPGEHYLNNYLRIVLVSLACQVGSDD 734
            ..|.....|.|:.......:|.....:|.    |:|.:...||.:|:..||..:::.....|.|:
plant   616 ISYKVVKIGADANQELMSGIKHFFIGVFQFAAGKLGWDPKQGESHLDAMLRGEVLTALAVFGHDE 680

  Fly   735 CYNQSANKLSEYL--YNGTAIEATLKTQAYCAGLRSTTNEIYSRVQSDLLSSSDSTD----RSLF 793
            ...::..:...:|  .|...:...::..||.|.::.......|..:| ||.....||    ::..
plant   681 TLKEAVRRFDAFLADRNTPLLPPDIRRAAYVAVMQRANKSDKSGYES-LLRVYRETDLSQEKTRI 744

  Fly   794 ISSL-GCSGST--SQLLDFLRLSLDTNNSLSYSERTSLLNSAYSRSEI---GLTASLEFLESNWE 852
            :.|| .|...|  ..:|:|: ||.:..|.          ::.|..|.:   |...:.::|:..||
plant   745 LGSLASCPDPTIVQDVLNFV-LSDEVRNQ----------DALYGLSGVSWEGREVAWKWLQEKWE 798

  Fly   853 AYANLSDS----AKPLDAALRGIATYVVSEKQKTRLNALVDVVEADGPSYINDDLSTTIDSRITS 913
            ...|...|    .:.:.|.:...|::   ||.|.        ||....:.....::.|:...|..
plant   799 YIGNTWGSGFLITRFISAVVSPFASF---EKAKE--------VEEFFATRSKPSMARTLKQSIER 852

  Fly   914 NFAWLEVNRDPVLNWIEDSLKENGSPSLTSSITT 947
                :.:|    .||:|...||:....|.:.:::
plant   853 ----VHIN----ANWVESIKKEDNLTQLVAQLSS 878

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31343	NP_732652.1	Peptidase_M1	57..446	CDD:279741	147/400 (37%)
		M1_APN_2	65..517	CDD:189008	163/463 (35%)
		ERAP1_C	591..886	CDD:288671	69/314 (22%)
APM1	NP_195035.2	M1_APN-Q_like	18..453	CDD:341064	161/457 (35%)
APM1	NP_195035.2	ERAP1_C	536..855	CDD:403137	74/349 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X67
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920