Protein Alignment CG31343 and Erap1

DIOPT Version :10

• Sequence 1: NP_732652.1
• Gene: CG31343 / 326133
• FlyBaseID: FBgn0051343
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_109636.1
• Gene: Erap1 / 80898
• MGIID: 1933403
• Length: 930
• Species: Mus musculus
• Alignment Length: 987
• Identity: 281/987 - (28%)
• Similarity: 446/987 - (45%)
• Gaps: 138/987 - (13%)

  Fly    25 ILPLSL-----------DDGQLETKGAALFATSRVDDNSAGNYRLPNTTEPESYNVELWTNVHNG 78
            :|||.|           .:..:|:..|     |..|.....|.|||....|..|::.:..|:  .
Mouse     4 LLPLVLTFLSVSSPSWCQNSDIESLKA-----SNGDSFPWNNMRLPEYMTPIHYDLMIHANL--S 61

  Fly    79 DTEFNGTVNIDIRVLNETSNITLHYRQTSNFEATI-------ISRDVATPTAIPLTVTPELQREF 136
            ...|.|...::|.....||.|.:|.......:||:       :|.:       ||.|......|.
Mouse    62 TLTFWGKTEVEIIASRPTSTIIMHSHHLQISKATLRRGAGEMLSEE-------PLKVLEYPAHEQ 119

  Fly   137 LVLTQTTAGEAFGANTNWTITINYTGIHRSDMGGFYISSYTDDDGEQHFLATTQFESTNARHAFP 201
            :.|   .|.:...|.:.:|:.|:|.........|||.|:|...:||...||.||||.|.||.|||
Mouse   120 VAL---LAAQPLLAGSLYTVIIDYAANLSESFHGFYKSTYRTQEGEMRILAATQFEPTAARMAFP 181

  Fly   202 CYDEPARRANFTITIHHDPSYTAISNMP-VNTAATSSGVTA--FQTTPKMSTYLVAFIVSDFEST 263
            |:||||.:|:|:|.|..||.:.|||||| |.:...:.|:..  |..|.||||||||||:|||:|.
Mouse   182 CFDEPALKASFSIKIKRDPRHLAISNMPLVKSVNVAEGLIEDHFDITVKMSTYLVAFIISDFKSV 246

  Fly   264 TG-ELNGIRQRVFSRKGKQDQQEWALWSGLLVESSLASYFGVPFALPKLDQAGIPDFSAGAMENW 327
            :. ..:|::..|::...|.:|.::||.:.:.:......||.:|:.|||.|.|.||||.:||||||
Mouse   247 SKMTKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFNIPYPLPKQDLAAIPDFQSGAMENW 311

  Fly   328 GLATYREQYMWWNKQNSTINLKTNIANIIGHEYAHMWFGDLVSIKWWTYLWLKEGFATLFSYESN 392
            ||.||||..:.::|:.|:.:.|..|..|:.||.||.|||:||:::||..|||.||||....:.|.
Mouse   312 GLTTYRESSLLYDKEKSSASSKLGITMIVSHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSV 376

  Fly   393 DIAFPLWDTYQIFHVNDYNSALLNDALASAVPMTHYVQTPSEISNRYNTFSYAKPASVLYMFKNA 457
            .:..|.......|....:| |:..|||.|:.|::..|:.|::|...::..||.|.|.:|.|.::.
Mouse   377 TVTHPELKVEDYFFGKCFN-AMEVDALNSSHPVSTPVENPAQIREMFDDVSYEKGACILNMLRDY 440

  Fly   458 WTDKVFRTGLNKYLTKNQYTSCDEWDLFASF-----------------------------QESAD 493
            .:...|:.|:.:||.|..|.:....||:.|.                             ||..|
Mouse   441 LSADTFKRGIVQYLQKYSYKNTKNEDLWNSMMHICPTDGTQTMDGFCSRSQHSSSTSHWRQEVVD 505

  Fly   494 ELGFTLPASVDDIFSSWSHQAGYPLLTVT---RNYNAGTITITQKRYV--ANKTDTNSATWYVPL 553
                     |..:.::|:.|.|:||:|:|   ||     :.:.|:.|:  :.:.......|:|||
Mouse   506 ---------VKTMMNTWTLQKGFPLITITVSGRN-----VHMKQEHYMKGSERFPETGYLWHVPL 556

  Fly   554 NFATANKYDYRDTSATHYLLNVTETVISDVEASSDDWIIVNIQNSGYYRTLYDTQNYGLITAALK 618
            .|.|:     :..|...:||.....|:...||.  .||..|:..:|||...|....:..::..||
Mouse   557 TFITS-----KSDSVQRFLLKTKTDVLILPEAV--QWIKFNVGMNGYYIVHYADDGWASLSGLLK 614

  Fly   619 SQPWRFHPRNRAQLLYDTYIFVSTDRLSHSILLELLGYLTNEQQYAP-WSTANTILTVYDRYLRG 682
            .........:||.|:.:.:..||.::||....|:|..||.||.:..| :...|.::.:|....:.
Mouse   615 EAHTTISSNDRASLINNAFQLVSIEKLSIEKALDLTLYLKNETEIMPIFQALNELIPMYKLMEKR 679

  Fly   683 D--DSYYNFQDFVKRLIDPIFDKI------GVNEIPGEHYLNNYLRIVLVSLACQVGSDDCYNQS 739
            |  :....|:||:.:|:..:.||.      .|:|        ..||..|:.|||......|..::
Mouse   680 DMIEVETQFKDFLLKLLKDLIDKQTWTDEGSVSE--------RMLRSQLLLLACVRNYQPCVQRA 736

  Fly   740 ANKLSEY-LYNGT---AIEATLKTQAYCAGLRSTT--NEIYSRVQSDLLSSSDSTDRSLFISSLG 798
            .....|: ..||.   .|:.||  ..:..|.::|.  :.:||:.||.|    .||::|....||
Mouse   737 ERYFREWKSSNGNMSIPIDVTL--AVFAVGAQNTEGWDFLYSKYQSSL----SSTEKSQIEFSL- 794

  Fly   799 CSGSTSQLLDFLRLSLDTNNSLSYSERTSLLNSAYSRSEIGLTASLEFLESNWEAYANLSDSAKP 863
            |:....:.|.:| |.......:..::....:.:...|:.:|...:.:||..||      :...:.
Mouse   795 CTSKDPEKLQWL-LDQSFKGEIIKTQEFPHILTLIGRNPVGYPLAWKFLRENW------NKLVQK 852

  Fly   864 LDAALRGIATYVVSEKQKTRLNALVDVVEADGPSYINDD-----LSTTIDSRITSNFAWLEVNRD 923
            .:.....||..|:....:....|.::.|:....|...:.     :..||:: |..|..|::.|.|
Mouse   853 FELGSSSIAHMVMGTTDQFSTRARLEEVKGFFSSLKENGSQLRCVQQTIET-IEENIRWMDKNFD 916

  Fly   924 PVLNWIEDSLKE 935
            .:..|::....|
Mouse   917 KIRLWLQKEKPE 928

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31343	NP_732652.1	M1_APN-Q_like	65..510	CDD:341064	161/484 (33%)
		ERAP1_C	590..889	CDD:463368	73/313 (23%)
Erap1	NP_109636.1	M1_APN-Q_like	50..515	CDD:341064	162/486 (33%)
		ERAP1_C	586..905	CDD:463368	77/341 (23%)