Protein Alignment CG31343 and lta4h

DIOPT Version :9

• Sequence 1: NP_732652.1
• Gene: CG31343 / 326133
• FlyBaseID: FBgn0051343
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_998451.1
• Gene: lta4h / 406575
• ZFINID: ZDB-GENE-040426-2477
• Length: 611
• Species: Danio rerio
• Alignment Length: 590
• Identity: 132/590 - (22%)
• Similarity: 223/590 - (37%)
• Gaps: 140/590 - (23%)

  Fly    67 YNVELWTNVHNGDTEFNGTVNIDIRVLNET-SNITLHYR-----------QTSNFEATIISRDVA 119
            |:|:...:|      ..|.|.:.:.||.:. |::||..:           |.:.||.....:...
Zfish    25 YHVDFDRHV------LKGKVALTVEVLEDKFSSLTLDSKDLKISKVSANGQAAKFELGAKHKFKG 83

  Fly   120 TPTAIPLTVTPELQREFLVLTQTTAGEAFGANTNWTITINYTGIHRSDMGGFYISSYTDDDGEQH 184
            :|  :.:|:..||.|...|:.:.....:..|.....:|...|.                  |::|
Zfish    84 SP--LEITLPFELSRGQHVIVEIEYETSPTATALQWLTPKQTA------------------GKKH 128

  Fly   185 FLATTQFESTNARHAFPCYDEPARRANFTITIHHDPSYTAISNMPVNTAATSSG----------- 238
            ....:|.::|:.|...||.|.|        ::.|  :|.|..::|....|..|.
Zfish   129 PYLFSQCQATHCRTMVPCQDTP--------SVKH--TYYAQVSVPRELVALMSALRDGQEPDPSD 183

  Fly   239 ----VTAFQTTPKMSTYLVAFIVSDFESTTGELNGIRQRVFSRKGKQDQ--QEWALWSGLL-VES 296
                :..|:....|.:||:|.:|...||.  |: |.|.||:|.|...|:  .|:|....:| ...
Zfish   184 SSRVIYRFRQPVPMPSYLIAIVVGALESR--EI-GPRSRVWSEKEYVDEAAYEFAETETMLKTAE 245

  Fly   297 SLASYFGVPFALPKLDQAGI-PDFSAGAMENWGLATYREQYMWWNKQNSTINLKTNIANIIGHEY 360
            |||.    |:...:.|...: |.|..|.|||..|.......:..::         ::|.:|.||.
Zfish   246 SLAG----PYVWGQYDVLVLPPSFPYGGMENPCLTFVTPTVLAGDR---------SLAGVIAHEI 297

  Fly   361 AHMWFGDLVSIKWWTYLWLKEGFATLFSYESNDIA----------FPLWDTYQIFH--VNDYNSA 413
            :|.|.|:||:.:.|.:.||.||...   |....||          |.....::..|  |..:.:
Zfish   298 SHSWTGNLVTNRTWEHFWLNEGHTV---YIERMIARCMEGEQLRQFKGIGGWKELHESVKQFGA- 358

  Fly   414 LLNDALASAVPMTHYVQTPSEISNRYNTFSYAKPASVLYMFKNAW-TDKVFRTGLNKYLTKNQYT 477
              |:.|.:.||..|.|.|    ...:::..|.|..::||..:... ..:||...:..|:....|.
Zfish   359 --NNVLTNLVPNLHEVDT----DEAFSSVPYEKGFALLYHLEELMGGPEVFMGFVKSYIQLFAYG 417

  Fly   478 S--CDEWD--LFASFQESADELGFTLPASVDDIFSSWSHQAGYPLLTVTRNYNA----GTITITQ 534
            |  .:||.  ||..|::..|.|.     .||  :::|.|..|  :..|...|:.    ...::.|
Zfish   418 SVTTEEWKNYLFTYFKDKVDILN-----KVD--WNAWMHTPG--MAPVRPQYDTTMADACTSLCQ 473

  Fly   535 KRYVANKTDTNSATWYVPLNFATANKYDYRDTSATH------YLLNVTETVISDVEASSDDWIIV 593
            |...|.:.|..|.|           :.|.:..::..      .||......:|.|:...:.:.:.
Zfish   474 KWVKAKEADLASFT-----------EADVKQLNSPQLIEFMALLLQEDPLPLSHVKKMGEVYKLN 527

  Fly   594 NIQNS 598
            ||:|:
Zfish   528 NIKNA 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31343	NP_732652.1	Peptidase_M1	57..446	CDD:279741	96/421 (23%)
		M1_APN_2	65..517	CDD:189008	116/497 (23%)
		ERAP1_C	591..886	CDD:288671	3/8 (38%)
lta4h	NP_998451.1	leuko_A4_hydro	18..607	CDD:274120	132/590 (22%)
		M1_LTA4H	18..449	CDD:189006	114/492 (23%)
		Leuk-A4-hydro_C	467..606	CDD:286244	14/77 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900