DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31343 and CG7653

DIOPT Version :9

Sequence 1:	NP_732652.1	Gene:	CG31343 / 326133	FlyBaseID:	FBgn0051343	Length:	961	Species:	Drosophila melanogaster
Sequence 2:	NP_001356886.1	Gene:	CG7653 / 34935	FlyBaseID:	FBgn0028935	Length:	710	Species:	Drosophila melanogaster

Alignment Length:	694	Identity:	162/694 - (23%)
Similarity:	295/694 - (42%)	Gaps:	100/694 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FSLILLLAVCSLQARLILPLSLDDGQLETKGAALFATSRVDDNSAGNYRLPNTTEPESYNVELWT 73
            :.|:|||.:|.:                    |..|.:::.|..    |||...:|..|::.|.|
  Fly    19 YGLLLLLCLCQV--------------------ACSAKTQLYDEP----RLPAKVKPFHYDIRLLT 59

  Fly    74 NVH-NGDTEFNGTVNIDIRVLNETSNITLH-------------YRQTSNFEATIISRDVATPTAI 124
            ::. :.:..:.|.|.|.|.....|:.:.||             :.:|||:...
  Fly    60 HLESSANHSYTGIVKISIHAQKTTNQVVLHVGRVSIESKKITLFGETSNYRLR------------ 112

  Fly   125 PLTVTPELQREFLVLTQTTAGEAFGANTNWTITINYTGIHRSDM-GGFYISSYTD-DDGEQHFLA 187
              :|.....|:::|:   |..::.....::.:::.:......|. .|::|..|.: ...|:.:.:
  Fly   113 --SVRFNNDRKYMVV---TFNQSLLMGKSYVLSVEFGRPMTMDQRDGYFIRHYINWKTSEKIWYS 172

  Fly   188 TTQFESTNARHAFPCYDEPARRANFTITIHHDPSYTAISNMPVNTAATSSGV-----TAFQTTPK 247
            .:.|.....|:..|.:|||:.:|.|.:|:.|...:.:..||.|.....:..:     :..:.||.
  Fly   173 VSHFNRNWIRNTMPSFDEPSLKATFNVTMGHHKRFQSYGNMKVQAVLPNREIQDYVWSVHEVTPT 237

  Fly   248 MSTYLVAFIVSDFE---STTGELNGIRQRVFSRKGKQDQQEWALWSGLLVESSLASYFGVPFALP 309
            :.|:|:||.|::|.   |....|:.:|.|..::........:|......:...|.....|...|.
  Fly   238 IPTHLLAFSVNNFNCRYSQAASLSPVRFRTCAQSADVRATSFAAQMAPQILEFLDRVLQVALPLE 302

  Fly   310 KLDQAGIPDFSAGAMENWGLATYREQYMWWNKQNSTINLKTNIANIIGHEYAHMWFGDLVSIKWW 374
            |:||..:.||...||||:||..||.:::...:.......|.....:|.||.|||||.:|:.:..:
  Fly   303 KIDQLVVDDFPTEAMENFGLVVYRSKHLLLREDGPMSKEKLQTLELIAHEMAHMWFDNLLGMDSY 367

  Fly   375 TYLWLKEGFATLFSYESNDIAFPLWDTYQIFHVND----------YNSALLNDALASAVPMTHYV 429
            :.|||.||.|..|.            :..:.|:..          ..|:::.::....:.:   |
  Fly   368 SDLWLTEGLAGYFK------------SLAVDHLQSKMGRRILLRYRESSMMYESQVGGISL---V 417

  Fly   430 QTPSEISNRYNTFSYAKPASVLYMFKNAWTDKVFRTGLNKYLTKNQYTSCDEWDLF-ASFQESAD 493
            ...|..|....|..|.|..|:..|......::.|..||.:::.:|.:.|... ||| .|.|.:::
  Fly   418 PLSSNASLNAETQLYQKATSLTSMLIGFLGNETFYDGLQRHMWQNSFGSSTP-DLFWRSLQLASE 481

  Fly   494 -ELGFTLPASVDDIFSSWSHQAGYPLLTVTRNYNAGTITITQKRYVANKTDTNSATWYVPLNFAT 557
             |..|.....|..|..:|:.|:||||:||.||   |:....::.:..|:  ::|..|::||.:..
  Fly   482 REATFDKTWDVKSIMDTWTMQSGYPLVTVIRN---GSEVFLKQGHALNR--SSSHLWWIPLTYLI 541

  Fly   558 ANKYDYRDTSATHYLL-NVTETVISDVEASSDDWIIVNIQNSGYYRTLYDTQNYGLITAALKSQP 621
            ......::.....:|. |.....::|: ...:.||::|:|..||||..||...:.|:...|.:..
  Fly   542 EGGSLSKNLKPKAWLSPNSHGIKLNDI-VPRNQWILLNLQAVGYYRVNYDELTWQLLATTLFNDF 605

  Fly   622 WRFHPRNRAQLLYDTYIFVSTDRLSHSILLELLGYLTNEQQYAP 665
            ...:..||||::.|.....:.|.|:.|..|.:|.|:.:|.:|.|
  Fly   606 RSINVLNRAQIVSDVLFLWNQDLLAWSTALNVLKYIIDEDEYEP 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31343	NP_732652.1	Peptidase_M1	57..446	CDD:279741	92/422 (22%)
		M1_APN_2	65..517	CDD:189008	108/487 (22%)
		ERAP1_C	591..886	CDD:288671	25/75 (33%)
CG7653	NP_001356886.1	M1_APN-Q_like	52..500	CDD:341064	105/480 (22%)
		ERAP1_C	574..>652	CDD:338125	26/76 (34%)
		dnaA	630..>701	CDD:234667	7/20 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462086
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950