Protein Alignment CG31343 and Lta4h

DIOPT Version :10

• Sequence 1: NP_732652.1
• Gene: CG31343 / 326133
• FlyBaseID: FBgn0051343
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_001025202.1
• Gene: Lta4h / 299732
• RGDID: 1311333
• Length: 611
• Species: Rattus norvegicus
• Alignment Length: 541
• Identity: 130/541 - (24%)
• Similarity: 204/541 - (37%)
• Gaps: 117/541 - (21%)

  Fly   101 LHYRQTSNFEATIISRDVATPTAIPLTV-------------TPELQREFLVL----TQTTAGE-- 146
            ||.|.:.:|     :|...|.|| .|||             |.:|..|.:|:    .:.|.||
  Rat    22 LHLRCSVDF-----ARRALTGTA-ALTVQSQEDNLRSLTLDTKDLTIEKVVINGQEVKYTLGESQ 80

  Fly   147 -------------AFGANTNWTITINYTGIHRSDMGGFYISSYTDDDGEQHFLATTQFESTNARH 198
                         |...|....|.|::....:|....:.....|  .|:||....:|.::.:.|.
  Rat    81 GYKGSPMEISLPIALSKNQEVVIEISFETSPKSSALQWLTPEQT--SGKQHPYLFSQCQAIHCRA 143

  Fly   199 AFPCYDEPARRANFTITIHHDPSYTAISNMPVNTAATSSGVT---------------AFQTTPKM 248
            ..||.|.|:.:.          :|||..::|....|..|.:.               .|.....:
  Rat   144 ILPCQDTPSVKL----------TYTAEVSVPKELVALMSAIRDGEAPDPEDPSRKIYRFNQRVPI 198

  Fly   249 STYLVAFIVSDFESTTGELNGIRQRVFSRKGKQDQQEWALWSGLLVESSL--ASYFGVPFALPKL 311
            ..||:|.:|...||   ...|.|..|:|.|   :|.|.:.:.....||.|  |...|.|:...:.
  Rat   199 PCYLIALVVGALES---RQIGPRTLVWSEK---EQVEKSAYEFSETESMLKIAEDLGGPYVWGQY 257

  Fly   312 DQAGI-PDFSAGAMENWGLATYREQYMWWNKQNSTINLKTNIANIIGHEYAHMWFGDLVSIKWWT 375
            |...: |.|..|.|||..|.......:..:|         :::|:|.||.:|.|.|:||:.|.|.
  Rat   258 DLLVLPPSFPYGGMENPCLTFVTPTLLAGDK---------SLSNVIAHEISHSWTGNLVTNKTWD 313

  Fly   376 YLWLKEGFATLFSYESNDIAFPLW-DTYQIFHVNDYNSALLN--DALASAVPMTHYVQTPSEISN 437
            :.||.||...   |....|...|: :.::.||.......|.|  .....:.|.|..|....::..
  Rat   314 HFWLNEGHTV---YLERHICGRLFGEKFRHFHALGGWGELQNTIKTFGESHPFTKLVVDLKDVDP 375

  Fly   438 --RYNTFSYAKPASVL-YMFKNAWTDKVFRTGLNKYLTKNQYTS--CDEWD--LFASFQESADEL 495
              .|::..|.|..::| |:.:.....:||...|..|:.|..|.|  .|:|.  |:|.|::..|.|
  Rat   376 DVAYSSIPYEKGFALLFYLEQLLGGPEVFLGFLKAYVEKFSYQSVTTDDWKSFLYAHFKDKVDLL 440

  Fly   496 GFTLPASVDDIFSSWSHQAGYPLLTVTRNYNA----GTITITQKRYVANKTDTNSATWYVPLNFA 556
            .     .||  :::|.:..|.|  .|..||:.    ..|.::|:...|.:.|.||        |:
  Rat   441 N-----QVD--WNAWLYAPGLP--PVKPNYDVTLTNACIALSQRWVTAKEEDLNS--------FS 488

  Fly   557 TANKYDYRDTSATHYLLNVTE 577
            ..:..|........:|..|.:
  Rat   489 IEDLKDLSSHQLNEFLAQVLQ 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31343	NP_732652.1	M1_APN-Q_like	65..510	CDD:341064	114/468 (24%)
		ERAP1_C	590..889	CDD:463368
Lta4h	NP_001025202.1	leuko_A4_hydro	6..608	CDD:274120	130/541 (24%)