DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31343 and Aopep

DIOPT Version :9

Sequence 1:	NP_732652.1	Gene:	CG31343 / 326133	FlyBaseID:	FBgn0051343	Length:	961	Species:	Drosophila melanogaster
Sequence 2:	XP_008769651.1	Gene:	Aopep / 290963	RGDID:	1309592	Length:	886	Species:	Rattus norvegicus

Alignment Length:	471	Identity:	90/471 - (19%)
Similarity:	161/471 - (34%)	Gaps:	147/471 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 QLETKGAALFATS------RVDDNSAGNYRLPNTTEPESYNVELWTNVHNGDTEFNGTVNIDIRV 92
            |:|::.|.:..|:      ::|.         ||..|:..:.|......:....|:...|.|.:.
  Rat   129 QMESEEAYILRTAEPCHVPKMDS---------NTFSPKMGHREFAVFGKSDQDAFDNDGNHDNKE 184

  Fly    93 LNETSNITLHYRQTSNF------------EATIISRDVATPTAIP----------LTVTP----- 130
            .:..|:.:.:...|.|.            :.:::..:.....|:|          ||..|
  Rat   185 HDSESSSSKYCCDTGNHGREDFLLVLDCCDLSVLKVEEVDVAAVPDLEKFTKAPNLTAAPEKRRC 249

  Fly   131 ELQREFLVLTQTT----------------AGEAFGANTNWTITINYTGI-------------HRS 166
            |:.|:.:.|....                .||....:..|::.|...|:             :::
  Rat   250 EIVRDLVALPADAWREQLDCYTRCSQAPGCGELLFDSDKWSLQIRKKGVPTAADFPHAIRIWYKT 314

  Fly   167 DMGGFYISSYTDDDGEQHFLATTQFESTNARHAFPCYDEPARRANFTITIHHDPSYTAISN---- 227
            ...|..::..:|.||..  ...|.....|.|..|||.:.|...:.:..|:....|:..:.:
  Rat   315 KPEGQSVTWTSDQDGRP--CVYTMGSPINNRALFPCQEPPVAMSTWQATVRAAASFVVLMSGEKS 377

  Fly   228 --------------------MPVNTAATSSGVTAFQTTPK------MSTYLVAFIVSD------- 259
                                ||.:|...:.|... :..||      ::.:.:....||
  Rat   378 AKPTPLREGYMSWHYYVTMPMPASTFTIAVGCWT-EMKPKTSPLDDLTEHTLPLRPSDADFRYGN 441

  Fly   260 ----------FESTTGEL-NGIRQRVFSRKGKQDQ-QEWALWSGLLVESSLASYFGV----PFAL 308
                      |:|.:... |.|..|||:....:.. :|..||   |:.|.|::...|    ||:
  Rat   442 TCSHMEYPCRFQSASAATQNIIPYRVFAPVCLEGACREALLW---LIPSCLSAAHSVLGTHPFS- 502

  Fly   309 PKLDQAGIPDFSAGAMENWGLATYREQYMWWNKQNSTINLKTNIANIIG----HEYAHMWFGDLV 369
             :||...:|.    ...:.|:|:....::    ..||:   |..:::.|    ||.||.|||..:
  Rat   503 -RLDILIVPT----NFPSLGMASPHIIFL----SQSTL---TGTSHLCGTRLCHEIAHAWFGLAI 555

  Fly   370 SIKWWTYLWLKEGFAT 385
            ..:.||..||.|||||
  Rat   556 GARDWTEEWLSEGFAT 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31343	NP_732652.1	Peptidase_M1	57..446	CDD:279741	85/442 (19%)
		M1_APN_2	65..517	CDD:189008	82/434 (19%)
		ERAP1_C	591..886	CDD:288671
Aopep	XP_008769651.1	GluZincin	250..697	CDD:301352	70/341 (21%)
Aopep	XP_008769651.1	Leuk-A4-hydro_C	743..884	CDD:286244
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349310
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830