Protein Alignment CG31343 and Trhde

DIOPT Version :10

• Sequence 1: NP_732652.1
• Gene: CG31343 / 326133
• FlyBaseID: FBgn0051343
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_666353.2
• Gene: Trhde / 237553
• MGIID: 2384311
• Length: 1066
• Species: Mus musculus
• Alignment Length: 1008
• Identity: 273/1008 - (27%)
• Similarity: 472/1008 - (46%)
• Gaps: 113/1008 - (11%)

  Fly    10 SLILLLAVCSLQARLILPLSLD-----------DGQL----ETKGAALFATSRVDDNSAG----- 54
            |::.||||..|  .::|.|..|           ||.|    |....:.|..|...::.||
Mouse    88 SIVALLAVTML--AVLLSLRFDECGASAAMPGTDGGLGGFPERDSNSSFPGSARRNHHAGGESSQ 150

  Fly    55 -----------------------------NYRLPNTTEPESYNVELWTNVHNGDTEFNGTVNIDI 90
                                         ..||....:|..||:.|...:.|  ..|:|.||::|
Mouse   151 RESGEVGTPGTPSAQPPSEEEREQWQPWTQLRLSGHLKPLHYNLMLTAFMEN--FTFSGEVNVEI 213

  Fly    91 RVLNETSNITLHYRQTSNFEATIISRDVATPTAIPLT---VTPELQREFLVLTQTTAGEAFGANT 152
            ...|.|..:.||..:.: .|...::.|.|. .|:|:.   :.|:.|...:||.:|     ..|..
Mouse   214 ACRNATRYVVLHASRVA-VEKVQVAEDRAF-GAVPVAGFFLYPQTQVLVVVLNRT-----LDAQR 271

  Fly   153 NWTITINYTGIHRSDMGGFYISSYTDDDGEQHFLATTQFESTNARHAFPCYDEPARRANFTITIH 217
            ::.:.|.|..:..:::.||:.|||. ..||:.||..|||..|:||.||||:|||..:|.|.|:|.
Mouse   272 HYNLKIIYNALIENELLGFFRSSYV-IHGERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIK 335

  Fly   218 HDPSYTAISNMPVNTAA--TSSGVT-AFQTTPKMSTYLVAFIVSDF---ESTTGELNGIRQRVFS 276
            |..:|.::|||||.|:.  ....|| .|..||.||||.:|:.:.:|   |:||  .:|:..|:::
Mouse   336 HQATYLSLSNMPVETSVFEEDGWVTDHFSQTPLMSTYYLAWAICNFTYRETTT--KSGVVVRLYA 398

  Fly   277 RKG--KQDQQEWALWSGLLVESSLASYFGVPFALPKLDQAGIPDFSAGAMENWGLATYREQYMWW 339
            |..  ::...::||.....:......||.||::|||||...:|.....|||||||:.:.||.:..
Mouse   399 RPDAIRRGSGDYALHITKRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILL 463

  Fly   340 NKQNSTINLKTNIANIIGHEYAHMWFGDLVSIKWWTYLWLKEGFATLFSYESNDIAFPLWD-TYQ 403
            :...|:|:...::..:|.||..|.||||||:..||..:|||||||..|.:...|..:|.|: ..|
Mouse   464 DPSVSSISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPAWNMEKQ 528

  Fly   404 IFHVNDYNSALLNDALASAVPMTHYVQTPSEISNRYNTFSYAKPASVLYMFKNAWTDKVFRTGLN 468
            .|..:..:..:|.|.|||:.|::..|...::|...::..:|.|.|:::.|..|.....||:.||.
Mouse   529 RFLTDVLHEVMLLDGLASSHPVSQEVLRATDIDRVFDWIAYKKGAALIRMLANFMGHSVFQRGLQ 593

  Fly   469 KYLTKNQYTSCDEWDLFASFQESADELGFTLPASVDDIFSSWSHQAGYPLLTVTRNYNA-GTITI 532
            .|||.::|.:....||:.:..|:....|..:  ::.::...|:.|.|||::|:..|..| ..|.|
Mouse   594 DYLTIHKYGNAARNDLWNTLSEALRRNGKYV--NIQEVMDQWTLQMGYPVITILGNTTAENRILI 656

  Fly   533 TQKRYV--------ANKTDTNSATWYVPLNFATANKYDYRDTSATHYLLNVTE-TVISDVEASSD 588
            ||:.::        |.:...:|..|.:||.....|: .:..:.|..::.|.:| ..|:.::..|
Mouse   657 TQQHFIYDIGAKTKALQLQNSSYLWQIPLTIVVGNR-SHVSSEAIIWVSNKSEHHRIAYLDRGS- 719

  Fly   589 DWIIVNIQNSGYYRTLYDTQNYGLITAALKSQPWRFHPRNRAQLLYDTYIFVSTDRLSHSILLEL 653
             ||:.||..:||:|..||.:|:.|:...|..........|||.|:.|.:.......|..:|.||:
Mouse   720 -WILGNINQTGYFRVNYDLRNWRLLIDQLIRNHEVLSVSNRAALIDDAFSLARAGYLPQNIPLEI 783

  Fly   654 LGYLTNEQQYAPWSTANTILTVYDRYLRGDDSYYNFQDFVKRLIDPIFDKIG--VNEIPGE---- 712
            :.||:.|:.:.||..|:..|...|:.|...::|..|.:::.:.:...:.|:|  .|...|.
Mouse   784 IRYLSEEKDFLPWHAASRALYPLDKLLDRMENYNIFNEYILKQVATTYIKLGWPRNNFNGSLVQA 848

  Fly   713 HYLNNYLRIVLVSLACQVGSDDCYNQSANKLSEYL-YNGTAIEATLKTQAYCAGLRSTTNEIYSR 776
            .|.:..||..::.|||..|:..|:.|::..:|::: .|...|...::...||.|:.....:::..
Mouse   849 SYQHEELRREVIMLACSFGNKHCHQQASTLISDWISSNRNRIPLNVRDIVYCTGVSLLDEDVWEF 913

  Fly   777 VQSDLLSSSDSTDRSLFISSLGCSGSTSQLLDFLRLSLDTNNSLSYSERTSLLNSAYSRSEIGLT 841
            :.....|::..:::.:.:.:|.||...:.|...|.|||::...|.......:::.|  |:..|..
Mouse   914 IWMKFHSTTAVSEKKILLEALTCSDDRNLLSRLLNLSLNSEVVLDQDAIDVIIHVA--RNPHGRD 976

  Fly   842 ASLEFLESNWEAYANLSDSAKPLDAAL-RGIATYVVSEKQKTRLNALVDVVEADGPSYINDDLST 905
            .:.:|....|:........|..:::.| .|:..::.:|.:...|...:       .||  |.:::
Mouse   977 LAWKFFRDKWKILNTRYGEALFMNSKLISGVTEFLNTEGELKELKNFM-------KSY--DGVAS 1032

  Fly   906 TIDSR----ITSNFAWLEVNRDPVLNWIEDSLK 934
            ...||    :.:|..|....:|.:..|:..:::
Mouse  1033 ASFSRAVETVEANVRWKRFYQDELFQWLGKAMR 1065

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31343	NP_732652.1	M1_APN-Q_like	65..510	CDD:341064	150/456 (33%)
		ERAP1_C	590..889	CDD:463368	71/306 (23%)
Trhde	NP_666353.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..176		8/57 (14%)
		M1_APN-Q_like	190..635	CDD:341064	151/458 (33%)
		ERAP1_C	720..1044	CDD:463368	76/334 (23%)