Protein Alignment CG31343 and T12E12.6

DIOPT Version :9

• Sequence 1: NP_732652.1
• Gene: CG31343 / 326133
• FlyBaseID: FBgn0051343
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_500831.2
• Gene: T12E12.6 / 188454
• WormBaseID: WBGene00020465
• Length: 641
• Species: Caenorhabditis elegans
• Alignment Length: 687
• Identity: 165/687 - (24%)
• Similarity: 262/687 - (38%)
• Gaps: 168/687 - (24%)

  Fly     7 NSFSLILLLAVCSLQARLILPLSLDDGQLETKGAALFATSRVDDNSAGNYRLPNTTEPESYNVEL 71
            :||.|:||                           ||.|:    ||     .|:...|.||::..
 Worm     3 SSFFLVLL---------------------------LFQTA----NS-----WPHNIIPLSYDLLF 31

  Fly    72 WTNVH--NGDTEFNGTVNIDIRVLNETSNITLHYRQTSNFE--ATIISRDVATPTAIPLTVTPE- 131
            ...:|  ||   |.|::.:...:.:.:.||||......:|.  :.|.|.|:..||...:.:..|
 Worm    32 KLPIHEFNG---FTGSMVLHFNLSSLSDNITLDAVDLHSFRNISLIRSADLTEPTLKSIKILKEK 93

  Fly   132 ---------LQREFLVLTQTTAGEAFGANTNWTITINYTGIHRSDMGGFYISSYTDDDGEQHFLA 187
                     ...::|:    |.||..|...|                    ||....:.....|.
 Worm    94 VELKFEKSLFPGQYLL----TIGEYNGRIGN--------------------SSEALFERRNPLLY 134

  Fly   188 TTQFESTNARHAFPCYDEPARRANFTITIHHDPSYTAISN---MPVNTAATSSGVTAFQTTPKMS 249
            ||..:..:||..|||.|.||.:|.|.::|.|.....|.||   |.|:........|.||.||.:.
 Worm   135 TTHLQPNHARRLFPCIDHPAVKALFRLSIVHPTDTVAQSNTIAMDVHVENRKWQRTIFQATPLLP 199

  Fly   250 TYLVAFIV-----------SDFEST---TGELNGIRQRVFSRKGKQDQQEWALWSGLLVESSLAS 300
            .|||||.|           :.|..|   .||..|:..||.         :.||.|..:    ||.
 Worm   200 AYLVAFSVMPDSNLQLSRQTSFGVTVRVNGESRGLVLRVL---------DCALASFEI----LAG 251

  Fly   301 YFGVPFALPKLDQAGIPDFSAGAMENWGLATYREQYMWWNKQNSTINLKTNIANIIGHEYAHMWF 365
            ...||..|.|:|...:|::. |.|||||..|..|..       :|.....::..:|.||.||.|.
 Worm   252 LIDVPLPLNKIDFILVPEYD-GGMENWGHITVSETL-------ATSGDDAHLIYLIAHEIAHHWI 308

  Fly   366 GDLVSIKWWTYLWLKEGFATLFSYESNDIAFPLWDTYQI--FHVNDY-NSALLNDALASAVPMTH 427
            |:..:|..|.::.|:|......:.::  :...|.|..::  |.:..| ...|:.|.|:..    |
 Worm   309 GNRATIDSWNWICLQEDLTDWMALKA--VKALLTDEIRLQRFQLAQYVEIQLVEDFLSPG----H 367

  Fly   428 YVQTPSEISNR-YNTFSYAKPASVLYMFKNAWTDK----VFRTGLNKYLTKNQYTSCDEWDLFAS 487
            .:..||:|:.. .|...|.|...:|...::...::    |.::.:..:.|.|..|       |.|
 Worm   368 SLYMPSKINQELINRHCYLKGVVLLDTLESVVGEQFMYSVIKSLVGSHSTYNLTT-------FTS 425

  Fly   488 FQESADELGFTLPASVDDIFSSWSHQAGYPLLTVTRNYNAGTITITQKRYVANKTDTNSATWYVP 552
            :   .|::.....|:|..|:..|....|||.:.|..|   |..:..|:        .:...|  |
 Worm   426 Y---FDQIRVDRNATVGQIYEYWYTTGGYPSILVENN---GPSSRLQQ--------LSRPLW--P 474

  Fly   553 LNFATANKYDYRDTSATHYLLNVTETVISD--VEASSDDWIIVNIQNSGYYRTLYDTQNYGLITA 615
            |...:.              |.:.:.|.|:  |.||.:..::||:..:.:.|..||:..:..|..
 Worm   475 LKMTST--------------LAIPQFVFSESIVFASENAPLLVNLNFTSFMRVNYDSLTWTAIFK 525

  Fly   616 ALKSQPWRFHPRNRAQLLYDTYIFVSTDRLSHSILLE 652
            .:..:|..|....||||:.|...|.:.|::.:..:|:
 Worm   526 YMFEEPELFSAVGRAQLVSDFCYFYANDKVDNGTILK 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31343	NP_732652.1	Peptidase_M1	57..446	CDD:279741	110/423 (26%)
		M1_APN_2	65..517	CDD:189008	122/490 (25%)
		ERAP1_C	591..886	CDD:288671	16/62 (26%)
T12E12.6	NP_500831.2	GluZincin	25..402	CDD:387391	110/430 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1087
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.870