Protein Alignment CG31343 and Y42A5A.1

DIOPT Version :10

• Sequence 1: NP_732652.1
• Gene: CG31343 / 326133
• FlyBaseID: FBgn0051343
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_505820.1
• Gene: Y42A5A.1 / 179536
• WormBaseID: WBGene00012776
• Length: 1045
• Species: Caenorhabditis elegans
• Alignment Length: 1029
• Identity: 243/1029 - (23%)
• Similarity: 408/1029 - (39%)
• Gaps: 212/1029 - (20%)

  Fly     8 SFSLILLLAVCSL-------QARLILPLSLD--------DGQLETKGAALFATSR----VDDNSA 53
            ||:||....:..|       |:..|||..:.        |..:.|....|..|:.    |..|:.
 Worm    83 SFALIYFFMIVPLTSSILPSQSSPILPSDISTIYQKSSTDFPIFTNSTELITTTEDPLYVHINNT 147

  Fly    54 GNYRL--PNTTEPESYNVELWTNVHNGDTEFNGTVNIDIRVLNETSNITLHYRQTSNFEATIISR 116
             |:||  |....|..|.|||...|....|...|:.|..::     .::.:|:  ||...:.|:..
 Worm   148 -NHRLQIPQIHIPLLYEVELKLFVPWRPTISFGSDNFSVK-----GHVRVHF--TSGGGSRILLH 204

  Fly   117 DVATPTAIPLTVTPELQREFLVLTQTTAGEAFGA------------NTNWTITINY-TGIHRSDM 168
            ..:........|..||.|.   :|....|..:..            ..|:|:.:.: :.|:.:..
 Worm   205 SDSKQHIGDCVVRDELNRN---ITVKLVGRQYSQILDLNLETDMIHGMNYTLDVAFKSAINLNLA 266

  Fly   169 GGFYISSYTDDDGEQHFLATTQFESTNARHAFPCYDEPARRANFTITIHHDPSYTAISNMPVNTA 233
            .|.:.:.||.:: |..::..||.:.:.||..|||.|.|..:|.|...|.|....|:|:||..|:.
 Worm   267 YGLFAAPYTFEN-ETRYVVATQLQISEARTVFPCIDVPDMKAQFDTVIIHPTGTTSIANMMENST 330

  Fly   234 ATSS--GVTAFQTTPKMSTYLVAFIVSDF---ESTTGELNGIRQRVFSRKGKQDQQEWALWSGLL 293
            ....  ..|.|..||.|||||.||.|||:   |:.:|  .|:|.||:....|       |....|
 Worm   331 KVDGEWTTTTFHRTPPMSTYLFAFSVSDYPYLETFSG--RGVRSRVYCDPTK-------LVDAQL 386

  Fly   294 VESSLA-------SYFGVPFALPKLDQAGIPDFSAGAMENWGLATYREQYMWWNKQNSTINLKTN 351
            :..|:.       .|||:|:.|.|||...:|..|..|||||||.|.|:....:.:....|:.|.:
 Worm   387 ITKSIGPVLDFYEDYFGIPYPLEKLDVVIVPALSVTAMENWGLITIRQTNGLYTEGRFAISQKHD 451

  Fly   352 IANIIGHEYAHMWFGDLVSIKWWTYLWLKEGFATLFSYESNDIAFPLWDTYQIFHVNDYNSALLN 416
            :..|:.||.||.|||:||::|||..|||.||||||.|..:.|........|:.........||..
 Worm   452 VQEIVAHELAHQWFGNLVTMKWWNDLWLNEGFATLISVRAVDFLENTTWRYEDSSAESQCVALRA 516

  Fly   417 DALASAVPMTHYVQTPSEISNRYNTFS--------YAKPASVLYMFKNAWTDKVFRTGLNKYLTK 473
            |.:.|..|::      .:.::.::::.        |.|.|.::.|.:....:.:||.||.::|..
 Worm   517 DQIDSISPVS------GKKNSNFDSYMEIQGKAIIYKKSAIIIRMIERLVEEDIFRQGLKRFLNT 575

  Fly   474 NQYTSCDEWDLFASFQESAD-ELGFTLPA---SVDDIFSSWSHQAGYPLLTVTRNYNAGTITITQ 534
            ..|.:.|..|||.......| ..|..|..   |:.|:..:|..||.:|::.|.|. ....:|:.|
 Worm   576 FLYKNADHEDLFNVLVYVHDSSAGGHLRGQNFSLSDVMDTWIRQAHFPVIHVNRK-EGSLVTLRQ 639

  Fly   535 KRYV-ANKTDTNSATWYVPLNFATANKYDYRDTSATH--YLLNVTETVISDVEASSDDWIIVNIQ 596
            ::|. ..:.:.....|.:|:      .|| ...|..|  :.|..|:..:.|:    ...::|:..
 Worm   640 EKYEHVPRDEPEKQVWKIPI------FYD-DPVSGKHKVFWLTDTQPKVFDM----GGLLVVDPH 693

  Fly   597 NSGYYRTLYDTQNYGLITAALKSQPWRFHPRNRAQLLYDTYIFVSTDRLSHSILLELLGYLTNEQ 661
            ...|.|..||.:.|..||.||..........:|::|:.||.......:|::.:...|..|::.|.
 Worm   694 QLTYMRLRYDMEMYSDITMALMDDFTMIPTNSRSRLIDDTLAMAENGQLTYKVPFNLTMYMSREI 758

  Fly   662 QYAPWSTANTILTVYDRYLRGDDSYYNFQDFVKRLIDPIFDKIGVN--EIPGEHYLNNY-LRIVL 723
            .|.|:.|.:..|..:...:...:.:..::.:::.::...|||....  ::..:|..:.: .|.::
 Worm   759 AYRPFQTFSAYLDFFLPRMYIHEGWSIYKKYLELVVGIPFDKFNAEGLDVSFDHNTDLFHTRQIV 823

  Fly   724 VSLACQVGSDDCYNQSANKLSEYLYNGTAIEATLKTQAYCAGLRSTTNEIYSRVQSDLLSSSDST 788
            |..||.:..:.|...:..:.:|...|             |:|            ::.|||..:
 Worm   824 VFRACGIEYEPCVRMAKQRFAELRVN-------------CSG------------ENQLLSGME-- 861

  Fly   789 DRSLFISSLGCSGSTSQLLDFLRLSLDTNNSLSYSERTSLLNSAYSRSEIGLTASLEFLESNW-- 851
                      |                  |.:.|..|..:.::|.:.   |.....:||...|
 Worm   862 ----------C------------------NKIPYYLRPHVYSAAIND---GTQEDFDFLYKKWMI 895

  Fly   852 EAY-------------ANLSDSAKPLDAALRGIATYVVSE----------KQKTRLNALVDVVEA 893
            |.|             .|:.:::   |.|.|.:......|          |:.::.|.::|::..
 Worm   896 EHYMMEHDNIFTGLCTTNIRENS---DRAWRQVIKNGARENVMVRAQLCSKKLSKNNFILDLLYE 957

  Fly   894 DGPSYINDDLSTTIDSRITSNFA-----WLEVNRD-------------PVLNWI 929
            | ..|:.:    .:|....|.||     :.::|.:             |.|.||
 Worm   958 D-KVYLKE----FVDKDRKSLFALQQLLYRKINYEEEVLKADEVFKPYPQLRWI 1006

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31343	NP_732652.1	M1_APN-Q_like	65..510	CDD:341064	137/481 (28%)
		ERAP1_C	590..889	CDD:463368	56/326 (17%)
Y42A5A.1	NP_505820.1	M1_APN-Q_like	160..618	CDD:341064	138/483 (29%)
		ERAP1_C	687..>939	CDD:463368	54/312 (17%)