Protein Alignment CG31343 and T16G12.1

DIOPT Version :10

• Sequence 1: NP_732652.1
• Gene: CG31343 / 326133
• FlyBaseID: FBgn0051343
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_499230.2
• Gene: T16G12.1 / 176416
• WormBaseID: WBGene00011803
• Length: 1890
• Species: Caenorhabditis elegans
• Alignment Length: 1083
• Identity: 272/1083 - (25%)
• Similarity: 422/1083 - (38%)
• Gaps: 252/1083 - (23%)

  Fly    25 ILPLSLD----DGQLETKGAALFATSRVDDNSAGNYRLPNTTEPESYNVE--LWTNVH------- 76
            |||...|    |.....|..:|:.|..         |||    |..|.::  ||...:
 Worm    53 ILPEHPDNFRQDKLAARKRQSLYVTKT---------RLP----PNLYAIDYSLWFQPYFPSPGVQ 104

  Fly    77 ---NGDTEFNGTVNIDIRVLNETSNITLHYRQTSNFEA---TIISRDVATPTAIPL-TVTPELQR 134
               ..:..|:|..:|.:..|..:....|:   ..||:.   .::..|   .|.:|: :::.:...
 Worm   105 YAPEKNFTFDGRASIQVEALVASDRFILN---AYNFKIQSYKVVDID---GTVVPINSISQDDTT 163

  Fly   135 EFLVLTQTTAGEAFGANTNWTITINYTGIHR--SDMGGFYISSYTDDDGEQHFLATTQFESTNAR 197
            :.|.|.....|...|...|  |...||||..  :| ||.|.:||.|..|..|::..|..|..:||
 Worm   164 QQLSLITNANGVVAGQIYN--IEFVYTGIINPYTD-GGVYYTSYNDPQGNTHYMIATHMEPFSAR 225

  Fly   198 HAFPCYDEPARRANFTITIHHDPSYTAISNMPVNTAATS-----SGVTAFQTTPKMSTYLVAFIV 257
            ..||..|||:.:|.||||:.:..|..|:||| :.|..|.     |.:| |..|||||:||:||.|
 Worm   226 KVFPSLDEPSYKAKFTITVQYPASQVALSNM-METEPTKIDNIWSTIT-FPQTPKMSSYLIAFAV 288

  Fly   258 SDF-ESTTGELNGIRQRVFSRKGKQDQQEWALWSGLLVESSLASYFGVPFALPKLDQAGIPDFSA 321
            ..: .|.....:....|.:...|.:...::|..:.......|..|.|:.|.|.|.||.|:|:|.|
 Worm   289 GPYVNSQYVNKHNTLTRAWGWPGTEQYLQFAAQNAGECLYQLGEYTGIKFPLSKADQLGMPEFLA 353

  Fly   322 GAMENWGLATYREQYMWWNKQNSTINLKTNIANIIGHEYAHMWFGDLVSIKWWTYLWLKEGFATL 386
            ||||||||..|:.||:.:|....|.......|.::.||.||.||||||:..||..|:|.||||..
 Worm   354 GAMENWGLIIYKYQYIAYNPTTMTTRNMEAAAKVMCHELAHQWFGDLVTTAWWDDLFLNEGFADY 418

  Fly   387 FSYESNDIAFP----LWDTYQIFHVNDYNSALLNDALASAVPMTHYVQTPSEISNRYNTFSYAKP 447
            |........:|    ..||.|:  :::....|..|....|.|:. |...|:     ::..:|.|.
 Worm   419 FMTFIQKSVYPQQATYLDTLQV--LDELQVGLTADVRYDAHPLV-YPDGPA-----FDDITYNKG 475

  Fly   448 ASVLYMFKNAWTDKVFRTGLNKYLTKNQYTSCDEWDLFASFQESA------DELGFTLPASVDDI 506
            ||:|.|..:.....||:.|:..||.|.||::.:::|||::..::|      |..|  ||.:|.|.
 Worm   476 ASMLRMLSDVLGADVFKQGIRAYLQKMQYSNANDFDLFSTLTDTAKSNNILDWCG--LPLNVTDF 538

  Fly   507 FSSWSHQAGYPLLTVTRNYNAGTITITQKRY--VANKTDTN-SATWYVPL---NFATANKYDY-- 563
            ...:.||..:||:....|...|..|.:|:.:  :::.|.|. :.||.:||   |...|:.|..
 Worm   539 MQPYIHQTNHPLIRYNNNQKIGGSTFSQEPFLDISDLTATPWNYTWSIPLTSANLRHADPYKQWL 603

  Fly   564 -RDTSATHYLLNVTETVISDVEASSDDWIIVNIQNSGYYRTLYDTQNYGLITAALKSQPWRFHPR 627
             |.....:...|:.|..|.:....:..|.:.:|.::.|.|.:||...:..|...:|...  .:..
 Worm   604 PRQQGCANMNENIQEERIKEPNKRAVQWELTSITSATYGRIIYDDIGFDRILKLIKQDD--INDN 666

  Fly   628 NRAQLLYDTYIFVSTDR-----LSHSILLELLGYL------TNEQQYAPWSTANTIL-TVYDRYL 680
            .:..||.|.|.::..::     ..::..|:|...:      ||...|..::.|..:| .:...|.
 Worm   667 LKLTLLADEYNYMLREKKANRPFGYNRFLDLAKVIFNTQSFTNYPSYGVFAQAQPVLEQIAQLYR 731

  Fly   681 RGDDSYYNFQDFVKRLIDPIFDKIGVNEIPGEHYLNNYLRI---------------VLVSLACQV 730
            .|.|:     :||.||....|.             |:|.::               |.:..|.:.
 Worm   732 DGIDA-----EFVPRLYKLFFQ-------------NSYNQLKWQDTSIWDTDTFSEVFLPFAVRY 778

  Fly   731 GSDDCYNQSANKLSEY------LYNGTA----IEATLKTQAYCAGLRSTTNEIYSRVQSD----L 781
            ...|..|::.|..:..      ..||||    ....|:...||...:      |:...||    :
 Worm   779 DIGDVQNRTLNMFANVKSACINSLNGTAWCNPYSTNLRKAIYCGAAK------YAPATSDYFFQM 837

  Fly   782 LSSSDS---------TDRSLFISSLGCSGSTSQLLDFLRL-SLDTNNS------LSYSERTS--- 827
            |.|.:.         .:....:..:.|:.|.:.|...:|| :..|.|.      |.|:...|
 Worm   838 LHSYNKEVITNPYFYQEYMALLEGMSCTQSPATLKVLIRLFTTSTLNPSTIFGFLKYNPAASDVL 902

  Fly   828 ---------LLNSAYSRSEIGLTASLEFLESNWEAY---ANLSDSAKPLDAALRGIATYVVSEKQ 880
                     |:||..      |.|.|:.:..||.:|   ..||.....|
 Worm   903 YNYFMANPQLVNSTM------LDAYLDAMTYNWNSYFREGQLSTLMNTL---------------- 945

  Fly   881 KTRLNALVDVVEADGPSYINDDLSTTIDSRITSNFAWLEVNRDPVLNWIEDSL------------ 933
             |..|...|:.:    .|||         |::..|.:......|..||:.|:|
 Worm   946 -TLTNDQFDIFD----FYIN---------RVSLMFEYKSTYALPTYNWLYDNLVVIGKTPWEKTP 996

  Fly   934 -------------------------KENGSPSLTSSITTILVS 951
                                     .||.:.|.||::|..|||
 Worm   997 NIDAVFPYYKLDLQVNIPGSGPYQWYENMTFSATSTVTFQLVS 1039

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31343	NP_732652.1	M1_APN-Q_like	65..510	CDD:341064	149/478 (31%)
		ERAP1_C	590..889	CDD:463368	70/370 (19%)
T16G12.1	NP_499230.2	M1_APN-Q_like	90..544	CDD:341064	148/474 (31%)
		ERAP1_C	639..931	CDD:463368	62/323 (19%)
		M1_APN-Q_like	1005..1471	CDD:341064	9/35 (26%)
		ERAP1_C	1542..1839	CDD:463368