DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31343 and rnpepl1

DIOPT Version :9

Sequence 1:	NP_732652.1	Gene:	CG31343 / 326133	FlyBaseID:	FBgn0051343	Length:	961	Species:	Drosophila melanogaster
Sequence 2:	NP_001335117.1	Gene:	rnpepl1 / 100535895	ZFINID:	ZDB-GENE-030131-5522	Length:	692	Species:	Danio rerio

Alignment Length:	728	Identity:	153/728 - (21%)
Similarity:	259/728 - (35%)	Gaps:	192/728 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VCSLQARLILPLSLDDGQLETKGAALFATSRVDDNSAGNYRLPNTTEPESYNVEL---------- 71
            :|..:..|.:|....:|     |.:|.....||..||.|:   :..:...::::|
Zfish     9 LCCCRKVLTVPGKSCEG-----GRSLAHCRLVDIASASNF---HCFKLRHFHLDLHLNFAVKRIT 65

  Fly    72 -W-----TNVHNGDTEFNGTVNIDIRVLNETSNITLHYRQTSNFEATIISRDVATPTAIPLTVTP 130
             |     |.|..|         :...:|:...::.:|            |.|...|.|   :..|
Zfish    66 GWQVLELTPVQPG---------VQSLILDTHPSLLIH------------SVDCKVPGA---SGAP 106

  Fly   131 ELQREFLVLTQTTAGEAF---GANTNWTITINYTGIHRSDMGGFYIS-SYTDDD----------- 180
            ::   ||.||...  |.|   |::.|.|:.......||:    |.:: .||..|
Zfish   107 DV---FLSLTYRV--EPFTDYGSSLNITLPAAVIRPHRA----FRVTVRYTTTDGPAIWWLDAEL 162

  Fly   181 --GEQHFLATTQFESTNARHAFPCYDEPARRANFTITIHHDPSYTAISNMPVNTAATSSGVTAFQ 243
              |:...|..||..|...|..|||:|.||.::.::.|:......|.:.:...:..:....|..|.
Zfish   163 TCGQTRPLVFTQGHSVCNRSFFPCFDTPAVKSTYSATVRVPEGVTVLMSASRSAYSKQDRVFQFS 227

  Fly   244 TTPKMSTYLVAFIVSDFESTTGELNGIRQRVF----------SRKGKQDQQEWALWSGLLVESSL 298
            ....:..||||.:..|.:...   .|.|.||:          |:.|...::...:..||
Zfish   228 MEYPVPAYLVALVAGDLQHAD---IGPRSRVWAEPCILTCAVSKLGGSVERWLNVAEGL------ 283

  Fly   299 ASYFGVPFALPKLDQAGI-PDFSAGAMENWGLATY-------REQYMWWNKQNSTINLKTNIANI 355
               || |:...:.|...: |.|...||||..| |:       .::::              :.::
Zfish   284 ---FG-PYVWGRYDLVFLPPSFPIVAMENPCL-TFIISSILESQEFL--------------LIDV 329

  Fly   356 IGHEYAHMWFGDLVSIKWWTYLWLKEGFATL----FSYESNDIAFPLWDTYQIFHVNDYNSALLN 416
            | ||.||.|||:.|:...|..:||.||.||.    .:.|:...||...:|  :|.:
Zfish   330 I-HEIAHGWFGNAVTNATWEEMWLSEGLATYAQRRITTEAYGEAFTCLET--VFRL--------- 382

  Fly   417 DALASAVPMTHYVQTPSEISNRY----------NTFSYAKP-ASVLYMFKNAWTDKVFRTGLNKY 470
            |||...:.:.......|::..::          |.|:|.|. ..|.|:.:.....|.|.:.|..|
Zfish   383 DALHRQMRLLGDNNPVSKLQAKFEPGVNPSSLMNLFTYEKGFCFVSYLSQLCGDIKRFDSFLRAY 447

  Fly   471 LTKNQYTSCDEWDLFASFQESADELGFTLPASVDDI-FSSWSHQAGYPLLTVTRNYNAGTITITQ 534
            :.|.:::|....||...|.....||.....|..:.: |..|.:..|.||  ...:.:||......
Zfish   448 IEKFRFSSVIAQDLLDFFLGFFPELKEGCVAQREGLEFERWLNGCGPPL--CEPDLSAGRTLTGP 510

  Fly   535 KRYVANKTDTNSATWYVPLNFATANKYDYRDTSATHYLLN-------VTETVISDVEASSDD--- 589
            .:::.:....::....|...|..::...::.......||:       |...:.|...|..||
Zfish   511 VQHLCDLWGNDAPDTQVISTFDLSSWSTFQTVLFLDRLLDRSPLSQEVMSLLSSCYAALLDDMNA 575

  Fly   590 -----WIIVNIQNSGY-----YRTLYDTQNYGLITAAL------------------KSQPWRFHP 626
                 |:.:.::||.|     .|:........:.|..|                  ::|. |.||
Zfish   576 EVQIRWLQIVVRNSFYPDLPRVRSFLHKHTSRMYTVPLYEDLCGGVMKCFAVEVFYQTQA-RLHP 639

  Fly   627 ---RNRAQLLYDT 636
               |...|:|:.|
Zfish   640 NLRRTLQQILFQT 652

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31343	NP_732652.1	Peptidase_M1	57..446	CDD:279741	96/453 (21%)
		M1_APN_2	65..517	CDD:189008	114/518 (22%)
		ERAP1_C	591..886	CDD:288671	14/72 (19%)
rnpepl1	NP_001335117.1	M1_LTA4H	36..490	CDD:189006	117/529 (22%)
rnpepl1	NP_001335117.1	Leuk-A4-hydro_C	507..649	CDD:312599	22/142 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590611
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830