Protein Alignment CG31343 and erap2

DIOPT Version :9

• Sequence 1: NP_732652.1
• Gene: CG31343 / 326133
• FlyBaseID: FBgn0051343
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: XP_005165525.1
• Gene: erap2 / 100144556
• ZFINID: ZDB-GENE-080402-6
• Length: 935
• Species: Danio rerio
• Alignment Length: 984
• Identity: 265/984 - (26%)
• Similarity: 461/984 - (46%)
• Gaps: 119/984 - (12%)

  Fly    11 LILLLAVCSLQARLILPLSLDDGQLETKGAALFATSRVDDNSAGNYRLPNTTEPESYNVELWTNV 75
            |:.|.::|.:|:......:.|:  |.|.|.. |..|:|        ||||...|..|::.:..|:
Zfish     9 LLFLESLCYVQSSESNSPTGDN--LATDGLP-FPWSKV--------RLPNYIVPVHYHLLIHPNL 62

  Fly    76 HNGDTEFNGTVNIDIRVLNETSNITLHYRQTSNFEATIISRDVATPTAIPLTVTP-ELQREFLVL 139
            ..  ..|.|:|.|:|.|.|.|:.:.||.:....:.||::....|..:...|:|.. .|..:..:.
Zfish    63 TT--LSFTGSVKIEIDVKNNTNWVVLHSKNLKIYTATVLDEHEAHLSEKTLSVLEYPLHEQIAIF 125

  Fly   140 TQ--TTAGE------AFGANTNWTITINYTGIHRSDMGGFYISSYTDDDGEQHFLATTQFESTNA 196
            :.  .|:||      .|||..:       .|.|     |||.|:|....||...||:|.||.|:|
Zfish   126 SPKILTSGEKYFLYLEFGAPLS-------DGFH-----GFYKSTYRTKSGETRVLASTHFEPTSA 178

  Fly   197 RHAFPCYDEPARRANFTITIHHDPSYTAISNMPV-NTAATSSGV--TAFQTTPKMSTYLVAFIVS 258
            |.|.||:|||..:||:|:.|...||:.|:||||: .|...|:|:  ..|:.:.|||:||:|||:.
Zfish   179 RMALPCFDEPVFKANYTVRIRRGPSHIALSNMPLEQTVEISNGLFEDHFEASVKMSSYLLAFIIC 243

  Fly   259 DFESTTG-ELNGIRQRVFSRKGKQDQQEWALWSGLLVESSLASYFGVPFALPKLDQAGIPDFSAG 322
            ||:|.:| ...||...:::...|..|.::||.:.|.:......||.:.:.|||||...||||.:|
Zfish   244 DFKSVSGLTATGINISIYAVPEKWHQTQYALEAALRLLEFYEQYFNILYPLPKLDLIAIPDFESG 308

  Fly   323 AMENWGLATYREQYMWWNKQNSTINLKTNIANIIGHEYAHMWFGDLVSIKWWTYLWLKEGFATLF 387
            |||||||.||||..:.::...|:.:.|..:..:||||.||.|||:||::.||..:||.||||...
Zfish   309 AMENWGLTTYRETSLLYDPDISSASDKLWVTMVIGHELAHQWFGNLVTMDWWNDIWLNEGFARYM 373

  Fly   388 SYESNDIAFPLWDTYQIFHVNDYNSALLNDALASAVPMTHYVQTPSEISNRYNTFSYAKPASVLY 452
            ...|.:..:|.......| ::....|:..|:|.|:.|::...::|::|...::|.||.|.|.:|:
Zfish   374 ESVSVEAVYPELKVEDHF-LDTCFGAIGRDSLNSSRPISSLAESPTQIKEMFDTVSYEKGACILH 437

  Fly   453 MFKNAWTDKVFRTGLNKYLTKNQYTSCDEWDLFASFQESADELGFTL------------------ 499
            |.::..||:.|::|:.:||.:..|.:....||:.|..::..|..|..
Zfish   438 MLRHFLTDEGFQSGIIRYLRRFSYCNARNEDLWDSLIKTCSEEDFAAGEYCYSSAQATKNAYRFA 502

  Fly   500 --PASVDDIFSSWSHQAGYPLLTVTRNYNAGTITITQKRYVANKTDTNSA--------TWYVPLN 554
              ...:..:.::|:.|.|.||:||.|  ....:.|.|:|::......:.:        .|::||.
Zfish   503 GEHVDLKKMMNTWTLQKGIPLVTVKR--QGRKLHIGQERFLKIVLPDDPSWHSLQDGYLWHIPLT 565

  Fly   555 FATANKYDYRDTSATHYLLNVTETVISDVEASSDDWIIVNIQNSGYYRTLYDTQNYGLITAALKS 619
            :.|:    :.|....|.|...::.::.|...   ||:.:|...:|||...||.:.:..:|..||.
Zfish   566 YKTS----HSDHEVKHILDKKSDVLLLDEHV---DWVKLNTDMNGYYIVHYDEEGWNALTELLKV 623

  Fly   620 QPWRFHPRNRAQLLYDTYIFVSTDRLSHSILLELLGYLTNEQQYAPWSTANTILTVYDRYL---R 681
            .......::||.|:::.:..|:..|||....|:|:.||.:|....|.......|..:.:.:   :
Zfish   624 NHTALSFKDRASLIHNAFQLVTAGRLSLDRALDLIAYLKSETHNVPLLQGLGYLQSFYKLIEKRK 688

  Fly   682 GDDSYYNFQDFVKRLIDPIFDKIGVNEIPGEHYLNNYLRIVLVSLACQVGSDDCYNQSANKLSEY 746
            ..|..:|.:.::.:....:.||...::  .....:..||..::||||.:....|..::......:
Zfish   689 IADVTHNLKTYILQYFKDVIDKQSWSD--DGMVSDRRLREDVLSLACDLDYPPCLEKAERLFVSW 751

  Fly   747 L-YNGT-AIEATLKTQAYCAGLRSTTNEIYSRVQSDLLSSSDSTDRSLFISSLGCSGSTSQLLDF 809
            : .||| ::...:....|..|.:..:..:|...|..:  |...|::|.|:|:|..|..:.:|...
Zfish   752 VKSNGTISLPTDVSETVYMVGAQDDSGWVYLLRQYGV--SMCETEKSKFLSALTSSKDSEKLSRL 814

  Fly   810 LRLSLD-----TNN--SLSYSERTSLLNSAYSRSEIGLTASLEFLESNWEAYANLSDSAKPLDAA 867
            |:|.::     |.|  ||.|         ..:|:.:|...:.:|::.:|      ::..:.....
Zfish   815 LQLGMEGTVIKTQNLPSLIY---------MVARNPVGHFLAWDFVKKHW------NELVEKFPLG 864

  Fly   868 LRGIATYVVSEKQKTRLNALVDVVEADGPSY---INDDLS-----TTIDSRITSNFAWLEVNRDP 924
            ..||...:|.  ..|:.::..::.|.:  |:   |.:.:|     ......:..|..||:.|.:.
Zfish   865 SFGIREIIVG--TVTQFSSTEELREVE--SFFKSIQEQVSQLRIIQVATENVEKNIVWLKRNLET 925

  Fly   925 VLNWIEDSL 933
            :..|::..|
Zfish   926 MRTWLQRRL 934

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31343	NP_732652.1	Peptidase_M1	57..446	CDD:279741	143/401 (36%)
		M1_APN_2	65..517	CDD:189008	157/484 (32%)
		ERAP1_C	591..886	CDD:288671	64/306 (21%)
erap2	XP_005165525.1	Peptidase_M1	44..432	CDD:279741	143/402 (36%)
		M1_APN_2	52..522	CDD:189008	157/484 (32%)
		ERAP1_C	595..911	CDD:288671	68/338 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590505
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X67
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950