DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31300 and CG6908

DIOPT Version :9

Sequence 1:	NP_651373.2	Gene:	CG31300 / 326132	FlyBaseID:	FBgn0051300	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_650105.1	Gene:	CG6908 / 41410	FlyBaseID:	FBgn0037936	Length:	449	Species:	Drosophila melanogaster

Alignment Length:	449	Identity:	108/449 - (24%)
Similarity:	191/449 - (42%)	Gaps:	60/449 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KLDAEQFNDDELEA--------PAWLNRQFIEEILSAYEDSPEL-KVVDLKITPASAQGDHYASV 59
            |...:|.||...|.        ||||::|..|.||.  .|.|:| |:...::.|.:.:|::|.::
  Fly    26 KQQRQQVNDMVRETEDIAIEPIPAWLDQQKFEPILE--RDFPDLKKIKSFRLEPTAGKGENYTTL 88

  Fly    60 MFRTTAECTTAKG-KFSRPLIIKAMPEQDGHKKDMLSESHLFETEIGMYCQVLPEFERILRESGD 123
            :.|...|.....| :.|...:.|.:| ..|:::::.|.. :|..|...|.|.:||||::.:::|.
  Fly    89 LLRANFELELNDGSEQSISYMAKILP-NSGNRENVASWK-VFYKERNTYGQYIPEFEQMYKDAGK 151

  Fly   124 DTKLFVPCIYHS-LE-PRKVMIFEDLVPQGY-YVIRDRPVAQEELKTAFAKLAKWHAISMKYIKE 185
            ... |.|..|.| :| ..::::.|||..:|: .|.|...:..:..:....|||::||.|....:.
  Fly   152 KIS-FGPRYYESQIELDDELIVLEDLGKRGFRNVDRQNGLDIQHTEATLEKLAQFHAASAVRFEL 215

  Fly   186 QPDFLKEFKYGLFEMPTVKTDPFITTGMQSFIEMLDRLPELRKYK-------------PHFEKIK 237
            :..:.:|:.                   |:...::|.|.|||:.:             .|.....
  Fly   216 KGSYPEEYN-------------------QNLCSVVDSLKELRENQLKAYIDAFPLYDASHLTNDV 261

  Fly   238 DKYMQRLQAVMKEYHENRKSDAFYVLCHGDFHLRNMMFKNNKGTGAHEDTMLVDFQISNLCPITI 302
            ..|..:...:.:.:....:.: |.||.|||....|:|::.:: .|...:...||.|:|.......
  Fly   262 QAYGSQADDMFQSFAPKIEGE-FRVLNHGDAWCNNIMYQYDE-AGKLAEVNFVDLQMSRFSSPAQ 324

  Fly   303 DLTYSIYMLMEPEQRREMGKDLINHYLTVLVATLKSIGYPGELPTQAKLWDEIHKNKYYDFFL-- 365
            ||.|.|....|.:.:......||..|...|:.:||.:.||..||:...|...|.  .|.|:.|
  Fly   325 DLLYLILSSTELDIKIAKFDYLIKFYHEKLIESLKLLKYPKPLPSLRSLHQSIF--IYGDWILPI 387

  Fly   366 LSTFLPLILAIKSKSFKVNDLIQ----DPETRQKTYFLDTYVKDVSKLLPKFEQLGYFK 420
            :|..|||:|........::.|:.    ..:.|...:.....:|...::||...:.|.|:
  Fly   388 VSILLPLVLIDGGDDANMDSLMDGEGAGDKIRNNMFKNHRVIKHQKEILPWAHRRGAFE 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31300	NP_651373.2	EcKinase	52..341	CDD:281023	69/305 (23%)
CG6908	NP_650105.1	EcKinase	81..363	CDD:281023	69/305 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459754
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940