Protein Alignment CG31272 and SLC22A13

DIOPT Version :9

• Sequence 1: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_004247.2
• Gene: SLC22A13 / 9390
• HGNCID: 8494
• Length: 551
• Species: Homo sapiens
• Alignment Length: 548
• Identity: 118/548 - (21%)
• Similarity: 200/548 - (36%)
• Gaps: 154/548 - (28%)

  Fly    57 FNLML---LIVSIPAQSAAIFE----------SSSMSYIL-----PIAECDL-------RL-TLE 95
            |||..   |::|:|..:|...|          ::|:..||     ....||:       || :|:
Human    60 FNLSAAEQLVLSVPLDTAGHPEPCLMFRPPPANASLQDILSHRFNETQPCDMGWEYPENRLPSLK 124

  Fly    96 D-----------KGVLNAVAYAGMTISAIAWGYLADTKGRKKILYWGYLIDAVCVFGSALSQNFS 149
            :           |....:|..||:.:..:.:|.|.|..|||..:....|:..:....:|...:|.
Human   125 NEFNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLATAFVPSFE 189

  Fly   150 MLVMFKFLGGLVVNGPAAVLFTYLTEMHGPKHRSSVLMIVGMVTSTATVSLPLLAWGIFPRDWDF 214
            :.:..:|.....|.|.:....|.|||..||..|:..:::.....|...:.|..||:|.
Human   190 LYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLGQMVLAGLAYGF------- 247

  Fly   215 EFWGLQVHSWQIFLFVLGIPSLISGLIFCSMPESPRFLMAQGRNEEALQAFKQIYHVNTRKPKDS 279
                   .:|::.......|.|:....|.::|||.|:|:.:||.:||:|..::...||.||
Human   248 -------RNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRK---- 301

  Fly   280 YPIKALIQEVPNRKAAQNEVIYTIEEKSGEVPTKRQSRTLAESLRAGLQQMKPLVRKPLLGLAIC 344
                 |..|:.|:         .:.||:|      .|....:..|      .|.:||..|.:...
Human   302 -----LSPELMNQ---------LVPEKTG------PSGNALDLFR------HPQLRKVTLIIFCV 340

  Fly   345 CYVMQFGIFLGMNTIRLWLPQLFASMAEYEALHAGD-GLDVSMCTILEFSVNQTAETALNYADAC 408
            .:|...| :.|:                  :|..|| ||||
Human   341 WFVDSLG-YYGL------------------SLQVGDFGLDV------------------------ 362

  Fly   409 SEPKVISMDMYLNNIIVSATGFVGYFFAGGILRALGPKRMMTYGLFLSGTFGLMLYFSVSSLMTL 473
                      ||..:|..|........:..:::..|.|......|.|.|...:::.|..:.|..:
Human   363 ----------YLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIFIPADLPVV 417

  Fly   474 IVSATFLTITG-------IAVSSLLGAVVALFPTQLRTVVVAIAMMCGRFGALSGNLLFPVFVQT 531
            :   |.|.:.|       ..:|.:..|  .||||.||...:.:..:..|.    |.:|.|:.:..
Human   418 V---TMLAVVGKMATAAAFTISYVYSA--ELFPTILRQTGMGLVGIFSRI----GGILTPLVILL 473

  Fly   532 G---CLPPFIMVSSVLILSGILSISLPD 556
            |   ...|.::..|:.|::|:|...||:
Human   474 GEYHAALPMLIYGSLPIVAGLLCTLLPE 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	113/537 (21%)
		2A0115	74..524	CDD:273327	101/491 (21%)
SLC22A13	NP_004247.2	2A0119	12..510	CDD:273328	118/548 (22%)
		MFS	139..500	CDD:119392	99/466 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..551

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153556
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840