Protein Alignment CG31272 and SLC22A8

DIOPT Version :9

• Sequence 1: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_001171661.1
• Gene: SLC22A8 / 9376
• HGNCID: 10972
• Length: 542
• Species: Homo sapiens
• Alignment Length: 501
• Identity: 109/501 - (21%)
• Similarity: 188/501 - (37%)
• Gaps: 111/501 - (22%)

  Fly    67 PAQSAAIFESSSMSYILPIAECDLRLTLED-KGVLNAVAYAGMTISAIAWGYLADTKGRKKILYW 130
            |.....::.|:..|.   :.|.||...... |.:..::..||:.|..:..|.|:|..||:.||..
Human    94 PCLDGWVYNSTKDSI---VTEWDLVCNSNKLKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTC 155

  Fly   131 GYLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNGPAAVLFTYLTEMHGPKHRSSVLM--IVGMVT 193
            .||:.|....|:|.|..|.:.::|:||.|..::|  ..|.|.:..:.....|...:|  .:|...
Human   156 SYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISG--ITLSTVILNVEWVPTRMRAIMSTALGYCY 218

  Fly   194 STATVSLPLLAWGIFPRDWDFEFWGLQVHSWQIFLFVLGIPSLISGLIFCSMPESPRFLMAQGRN 258
            :.....||.||:.| |:             |:.....:.||..:..|.....|||.|:|:..|::
Human   219 TFGQFILPGLAYAI-PQ-------------WRWLQLTVSIPFFVFFLSSWWTPESIRWLVLSGKS 269

  Fly   259 EEALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQNEVIYTIEEKSGEVPTKRQSRTLAESL 323
            .:||:..:::...|.:|.:             ..:.:..|:...:::   |:...:...|.::..
Human   270 SKALKILRRVAVFNGKKEE-------------GERLSLEELKLNLQK---EISLAKAKYTASDLF 318

  Fly   324 RAGLQQMKPLVRKPLLGLAICCYVMQFGIFLGMNTIRLWLPQLFASMAEYEALHAGDGLDVSMCT 388
            |.      |::|:           |.|.:.|.      |    ||:...|.:|..|
Human   319 RI------PMLRR-----------MTFCLSLA------W----FATGFAYYSLAMG--------- 347

  Fly   389 ILEFSVNQTAETALNYADACSEPKVISMDMYLNNIIVSATGFVGYFFAGGILRALGPKRMMTYGL 453
            :.||.||                      :|:..||.........|.....|..||........|
Human   348 VEEFGVN----------------------LYILQIIFGGVDVPAKFITILSLSYLGRHTTQAAAL 390

  Fly   454 FLSGTFGLMLYFSVSSLMTLIVSATFLTITG-----IAVSSLLGAVVALFPTQLRTVVVAIAMMC 513
            .|:|...|.|.|....|.|:   .|.|.:.|     .:.|.|......|:||.:|...:.::.:.
Human   391 LLAGGAILALTFVPLDLQTV---RTVLAVFGKGCLSSSFSCLFLYTSELYPTVIRQTGMGVSNLW 452

  Fly   514 GRFGALSGNLLFPVFVQTGCLPPF---IMVSSVLILSGILSISLPD 556
            .|.    |:::.|:...||.:.||   |:.....:|.|..::.||:
Human   453 TRV----GSMVSPLVKITGEVQPFIPNIIYGITALLGGSAALFLPE 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	107/498 (21%)
		2A0115	74..524	CDD:273327	98/457 (21%)
SLC22A8	NP_001171661.1	2A0119	11..503	CDD:273328	109/501 (22%)
		MFS	96..493	CDD:119392	106/496 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	515..542

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153592
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840