Protein Alignment CG31272 and SLC22A6

DIOPT Version :9

• Sequence 1: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_004781.2
• Gene: SLC22A6 / 9356
• HGNCID: 10970
• Length: 563
• Species: Homo sapiens
• Alignment Length: 607
• Identity: 128/607 - (21%)
• Similarity: 219/607 - (36%)
• Gaps: 184/607 - (30%)

  Fly     4 KNIKTAIP------------EKSKGLE--NDKDADGNSDS----TAEAEATPTEEGSATFDKAIE 50
            :|...|||            .|:.|||  ..:|..|..:|    |:.....|...|:       |
Human    38 QNFTAAIPTHHCRPPADANLSKNGGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGT-------E 95

  Fly    51 GAGFGIFNLMLLIVSIPAQSAAIFESSSMSYILPIAECDLRLTLED-KGVLNAVAYAGMTISAIA 114
            ..|.|        .:.|.....|:::|:....: :.|.||..:... :.:..::...|:.:.|:.
Human    96 ANGTG--------ATEPCTDGWIYDNSTFPSTI-VTEWDLVCSHRALRQLAQSLYMVGVLLGAMV 151

  Fly   115 WGYLADTKGRKKILYWGYLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNGPAAVLFTYLTEMHGP 179
            :|||||..||:|:|...||..||....:|.:.||.:...|:.|.|:.:.|.:....|...|....
Human   152 FGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPI 216

  Fly   180 KHRSSVLMIVGMVTSTATVSLPLLAWGIFPRDW-------DFEFWGLQVHSWQIFLFVLGIPSLI 237
            ..|:.|..::|.|.|.....|..:|:.: |. |       ...|:...::||   .|:
Human   217 HTRACVGTLIGYVYSLGQFLLAGVAYAV-PH-WRHLQLLVSAPFFAFFIYSW---FFI------- 269

  Fly   238 SGLIFCSMPESPRFLMAQGRNEEALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQNEVIYT 302
                     ||.|:..:.||.:..|:|.:::..:|.::.:.:    .|..|| .|.:.|.|:
Human   270 ---------ESARWHSSSGRLDLTLRALQRVARINGKREEGA----KLSMEV-LRASLQKEL--- 317

  Fly   303 IEEKSGEVPTKRQSRTLAESLRAGLQQMKPLVRKPLLGLAICCYVMQFGIFLGMNTIRLWLPQLF 367
                           |:.:...:.::    |:|.|.|.....|..|            ||    |
Human   318 ---------------TMGKGQASAME----LLRCPTLRHLFLCLSM------------LW----F 347

  Fly   368 A-SMAEYEALHAGDGLDVSMCTILEFSVNQTAETALNYADACSEPKVISMDMYLNNIIVSATG-- 429
            | |.|.|..:....|..||                                :||..:|..|..
Human   348 ATSFAYYGLVMDLQGFGVS--------------------------------IYLIQVIFGAVDLP 380

  Fly   430 --FVGYFFAGGILRALGPKRMMTYGLFLSGTFGLM----------LYFSVSSLMTLIVSATFLTI 482
              .||:.    ::.:||.:......|.|:|...|:          :..|::.|....::|:|..|
Human   381 AKLVGFL----VINSLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCI 441

  Fly   483 ---TGIAVSSLLGAVVALFPTQLRTVVVAIAMMCGRFGALSGNLL---------FPVFVQTGCLP 535
               ||           .|:||.:|...:.:.....|.|::...|:         .|:|:. |.:|
Human   442 FLYTG-----------ELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIY-GAVP 494

  Fly   536 PFIMVSSV-LILSGILSISLPD 556
              :..|:| ::|...|...|||
Human   495 --VAASAVTVLLPETLGQPLPD 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	108/528 (20%)
		2A0115	74..524	CDD:273327	97/475 (20%)
SLC22A6	NP_004781.2	2A0119	11..515	CDD:273328	128/607 (21%)
		MFS	135..505	CDD:119392	100/483 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	525..563

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153595
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840