Protein Alignment CG31272 and SLC22A5

DIOPT Version :9

• Sequence 1: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_001295051.1
• Gene: SLC22A5 / 6584
• HGNCID: 10969
• Length: 581
• Species: Homo sapiens
• Alignment Length: 535
• Identity: 120/535 - (22%)
• Similarity: 199/535 - (37%)
• Gaps: 168/535 - (31%)

  Fly    74 FESSSMSYILPIAECDLRLTLEDKGVLNAVA--------------------------------YA 106
            :|.|...|:..|      :|.:|.|..||:.                                :.
Human   117 WEFSQDVYLSTI------VTEQDSGAYNAMKNRMGKKPALCLPAQWNLVCEDDWKAPLTISLFFV 175

  Fly   107 GMTISAIAWGYLADTKGRKKILYWGYLIDAVCVFGSALSQNFSM-LVMFKFLG-GLVVNGPAAVL 169
            |:.:.:...|.|:|..|||.:|:....:.....|....|:||.| :|:|..:| |.:.|..||
Human   176 GVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAA-- 238

  Fly   170 FTYLTEMHGPKHRSSVLMIVGMVTSTATVS---------LPLLAWGIFPRDWDFEFWGLQVHSWQ 225
            |...||:.|..        |.::.||..|.         |||.|:  |.||            |:
Human   239 FVLGTEILGKS--------VRIIFSTLGVCIFYAFGYMVLPLFAY--FIRD------------WR 281

  Fly   226 IFLFVLGIPSLISGLIFCSMPESPRFLMAQGRNEEALQAFKQIYHVNTRKPKDSYPIKALIQEVP 290
            :.|..|.:|.::...::..:|||||:|::|||.|||                          ||.
Human   282 MLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEA--------------------------EVI 320

  Fly   291 NRKAAQ-NEVIYTIEEKSGEVPTKRQSRTLAESLRAGLQQMKPLVRKPLLGLAICCYVMQFGIFL 354
            .||||: |.::         ||:.....:..:.|.:..||...:
Human   321 IRKAAKANGIV---------VPSTIFDPSELQDLSSKKQQSHNI--------------------- 355

  Fly   355 GMNTIRLWLPQLFASMAEYEALHAGDGLDVSMCTILEFSVNQTAETALNYADACSEPKVISMDMY 419
             ::.:|.|                    ::.|.||:...:..|  .::.|.....:...:..|::
Human   356 -LDLLRTW--------------------NIRMVTIMSIMLWMT--ISVGYFGLSLDTPNLHGDIF 397

  Fly   420 LNNIIVSATGFVGYFFAGGILRALGPKRMMTYGLFLSGTFGLMLYFSVSSLMTLIVSATFLTITG 484
            :|..:.:......|..|..:|:.|..:..|...|||.|:..|.:......|..|   ||.|.:.|
Human   398 VNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLVPPDLYYL---ATVLVMVG 459

  Fly   485 -----IAVSSLLGAVVALFPTQLRTVVVAIAMMCGRFGALSGNLLFPVFVQTGCLP---PFIMVS 541
                 .|.|.:......|:||.:|.:.|.::....|.    |::|.|.||..|...   |:|::.
Human   460 KFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRL----GSILSPYFVYLGAYDRFLPYILMG 520

  Fly   542 SVLILSGILSISLPD 556
            |:.||:.||::.||:
Human   521 SLTILTAILTLFLPE 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	118/532 (22%)
		2A0115	74..524	CDD:273327	106/498 (21%)
SLC22A5	NP_001295051.1	2A0119	12..544	CDD:273328	120/535 (22%)
		MFS	162..534	CDD:119392	109/481 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153577
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840