Protein Alignment CG31272 and SLC22A4

DIOPT Version :9

• Sequence 1: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_003050.2
• Gene: SLC22A4 / 6583
• HGNCID: 10968
• Length: 551
• Species: Homo sapiens
• Alignment Length: 498
• Identity: 110/498 - (22%)
• Similarity: 193/498 - (38%)
• Gaps: 127/498 - (25%)

  Fly    78 SMSYILPIAECDLRLTLEDK---GVLNAVAYAGMTISAIAWGYLADTKGRKKILYWGYLIDAVCV 139
            |....|.....:..|..||.   .:..::.:.|:.:.:...|.|:|..|||.:|:....:.....
Human   120 SQDVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQTGFS 184

  Fly   140 FGSALSQNFSML-VMFKFLG-GLVVNGPAAVLFTYLTEMHGPKHRSSVLMIVGMVTSTAT--VSL 200
            |....|.::.|. |:|..:| |.:.|  ..|.|...||:.|...| .:...:|:.|..|.  :.|
Human   185 FLQIFSISWEMFTVLFVIVGMGQISN--YVVAFILGTEILGKSVR-IIFSTLGVCTFFAVGYMLL 246

  Fly   201 PLLAWGIFPRDWDFEFWGLQVHSWQIFLFVLGIPSLISGLIFCSMPESPRFLMAQGRNEEALQAF 265
            ||.|:  |.||            |::.|..|.:|.::...::..:|||||:|::|.|..||
Human   247 PLFAY--FIRD------------WRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREA---- 293

  Fly   266 KQIYHVNTRKPKDSYPIKALIQEVP--NRKAAQNEVIYTIEEKSGEVPTKRQSRTLAESLRAGLQ 328
                             :.:||:..  |..|....:..::||.:   |.|:|...:.:..|.
Human   294 -----------------EDIIQKAAKMNNIAVPAVIFDSVEELN---PLKQQKAFILDLFRT--- 335

  Fly   329 QMKPLVRKPLLGLAICCYVMQFGIFLGMNTIRLWL---PQLFASMAEYEALHAGDGLDVSMCTIL 390
                      ..:||          :.:.::.||:   ...||...:...||....|:..:..::
Human   336 ----------RNIAI----------MTIMSLLLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALI 380

  Fly   391 EFSVNQTAETALNYADACSEPKVISMDMYLNNIIVSATGFVGYFFAGGILR--ALGP--KRMMTY 451
            |.....||...|.     :.|:         ..|::|.    .|:.||:|.  .|.|  ...::.
Human   381 EIPAYITAWLLLR-----TLPR---------RYIIAAV----LFWGGGVLLFIQLVPVDYYFLSI 427

  Fly   452 GLFLSGTFGLMLYFSVSSLMTLIVSATFLTITGIAVSSLLGAVVALFPTQLRTVVVAIAMMCGRF 516
            ||.:.|.||:...||:..:.|                      ..|:||.:|.:.|.:.....|.
Human   428 GLVMLGKFGITSAFSMLYVFT----------------------AELYPTLVRNMAVGVTSTASRV 470

  Fly   517 GALSGNLLFPVFVQTGC---LPPFIMVSSVLILSGILSISLPD 556
                |:::.|.||..|.   :.|:|::.|:.:|.|||::..|:
Human   471 ----GSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLFFPE 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	109/495 (22%)
		2A0115	74..524	CDD:273327	98/461 (21%)
SLC22A4	NP_003050.2	2A0119	12..518	CDD:273328	110/498 (22%)
		MFS	123..508	CDD:119392	108/492 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153576
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840