Protein Alignment CG31272 and SLC22A1

DIOPT Version :10

• Sequence 1: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: XP_005267160.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 573
• Species: Homo sapiens
• Alignment Length: 481
• Identity: 108/481 - (22%)
• Similarity: 189/481 - (39%)
• Gaps: 104/481 - (21%)

  Fly    67 PAQSAAIFESSSMSYILPIAECDLRLTLEDKGVLN---AVAYAGMTISAIAWGYLADTKGRKKIL 128
            |.|...::::...|.:     .:..|...|...|:   :...||....::..||.||..|||..|
Human   120 PCQDGWVYDTPGSSIV-----TEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCL 179

  Fly   129 YWGYLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNGPAAVLFTYLTEMHGPKHRSSVLMIVGMVT 193
            ....|::||.....|.|.|:..:::|:.|.|||..|.....:|.:||..|...|.:|.::..|..
Human   180 LGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAF 244

  Fly   194 STATVSLPLLAWGIFPRDWDFEFWGLQVHSWQIFLFVLGIPSLISGLIFCSMPESPRFLMAQGRN 258
            :...|:|..||:.: |.             |:.....:.:|:.:..|.:..:|||||:|::|.||
Human   245 TVGLVALTGLAYAL-PH-------------WRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRN 295

  Fly   259 EEALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQNEVIYTIEEKSGEVPTKRQSRTLAESL 323
            .||::....|...|.:.|.....:.:|.::|                      |::.|.:.|:..
Human   296 TEAIKIMDHIAQKNGKLPPADLKMLSLEEDV----------------------TEKLSPSFADLF 338

  Fly   324 RAGLQQMKPLVRKP---LLGLAICCYVMQFGIFL--GMNTIRLWLPQLFASMAEYEALHAGDGLD 383
            |.      |.:||.   |:.|.....|:..|:.|  |..:..|:|..|::::.|.      .|..
Human   339 RT------PRLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEI------PGAF 391

  Fly   384 VSMCTILEFS-VNQTAETALNYADACSEPKVISMDMYLNNIIVSATGFVGYFFAGGILRALGPKR 447
            :::.||.... :...|.:.|....||.....||.|::..|||:...|.:|
Human   392 IALITIDRVGRIYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMG--------------- 441

  Fly   448 MMTYGLFLSGTFGLMLYFSVSSLMTLIVSA----TFLTITGIAVSSLL----GAVVALFPTQLRT 504
                             .:::..|..:|:|    ||:...|:.|.|.|    |.:......:||.
Human   442 -----------------ITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIITPFIVFRLRE 489

  Fly   505 VVVAIAMMCGRFGALSGNLLFPVFVQ 530
            |..|:.::.  ||..:...|....::
Human   490 VWQALPLIL--FGQRTSKTLLTHLIE 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	synapt_SV2	15..556	CDD:130366	108/481 (22%)
SLC22A1	XP_005267160.1	2A0119	12..500	CDD:273328	105/466 (23%)