Protein Alignment CG31272 and Sv2b

DIOPT Version :9

• Sequence 1: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_001103223.1
• Gene: Sv2b / 64176
• MGIID: 1927338
• Length: 683
• Species: Mus musculus
• Alignment Length: 652
• Identity: 155/652 - (23%)
• Similarity: 253/652 - (38%)
• Gaps: 130/652 - (19%)

  Fly     1 MSEKNIKTAIPEKSKGLENDKDADGNSDSTAEAEATPTEEGSATFDKAIEGAGFGIFNLMLLIV- 64
            :..|..|.| |.::.||      .|.:|..|| .....||.:..::..|:..|.|.|...|..|
Mouse    59 VKSKQTKMA-PSRADGL------GGQADLMAE-RMEDEEELAHQYETIIDECGHGRFQWTLFFVL 115

  Fly    65 --SIPAQSAAIFESSSMSYILPIAECDLRLTLEDKGVLNAVAYAGMTISAIAWGYLADTKGRKKI 127
              ::.|....||   .:|:.||.||.|:.|:...||:|..:.|.||...|...|.|||..||||:
Mouse   116 GLALMADGVEIF---VVSFALPSAEKDMCLSSSKKGMLGLIVYLGMMAGAFILGGLADKLGRKKV 177

  Fly   128 LYWGYLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNGPAAVLFTYLTEMHGPKHRSSVLMIVGMV 192
            |.....|:|.....|:..|.:...:..:.:.|:.:.|...::|.|.:|....:.|...|..:|:.
Mouse   178 LSMSLAINASFASLSSFVQGYGAFLFCRLISGIGIGGSLPIVFAYFSEFLSREKRGEHLSWLGIF 242

  Fly   193 TSTATVSLPLLAWGIFPR-DWDFEF-WGLQVHSWQIFLFVLGIPSLISGLIFCSMPESPRFLMAQ 255
            ..|..:....:||.|.|. .|.|.. .....|||::|:.|..:|:.:|.:....||||||||:..
Mouse   243 WMTGGIYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPATVSMVALKFMPESPRFLLEM 307

  Fly   256 GRNEEALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQNEVIYTIEEKSGEVPTKRQSRTLA 320
            |:::||....||::..|.|           .:..|       |.::|:    ..:.|.:|.....
Mouse   308 GKHDEAWMILKQVHDTNMR-----------AKGTP-------EKVFTV----SHIKTPKQMDEFI 350

  Fly   321 E-SLRAGLQQMKPLVR-----KPLLGLAICCY------------VMQFGIFLGMNTIRLWLPQL- 366
            | ....|....:.|||     |.:...|:.|.            |:.|.:.|....:.:|.|.:
Mouse   351 EIQSSTGTWYQRWLVRFMTIFKQVWDNALYCVMGPYRMNTLILAVVWFTMALSYYGLTVWFPDMI 415

  Fly   367 -FASMAEYEA-LHAGDGLDVSMCTI---LEFSVNQTAETALN---------------YADACSEP 411
             :....||:: :....|..|...||   :|..::|..:...:               :.|.|...
Mouse   416 RYFQDEEYKSKMKVFFGEHVHGATINFTMENQIHQHGKLVNDKFIKMYFKHVLFEDTFFDKCYFE 480

  Fly   412 KVISMDMYLNNIIVSAT--------------------------------------------GFVG 432
            .|.|.|.|..|..:.:|                                            .|:|
Mouse   481 DVTSTDTYFKNCTIESTTFYNTDLYKHKFINCRFINSTFLEQKEGCHMDFEEDNDFLIYLVSFLG 545

  Fly   433 YF--FAGGILRAL-----GPKRMMTYGLFLSGTFGLMLYFSVSSLMTLIVSATFLTITGIAVSSL 490
            ..  ..|.|:.||     |..:|:...:.:|......|:|. :|...:|........|.||..:.
Mouse   546 SLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFFG-NSESAMIGWQCLFCGTSIAAWNA 609

  Fly   491 LGAV-VALFPTQLRTVVVAIAMMCGRFGALSGNLLFPVFVQTGCLPPFIMVSSVLILSGILSISL 554
            |..: |.|:||..|.....|.....:|||:.||.:|..||....:.|.::.::.|:..|::::.|
Mouse   610 LDVITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFVGITKVVPILLAAASLVGGGLIALRL 674

  Fly   555 PD 556
            |:
Mouse   675 PE 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	136/588 (23%)
		2A0115	74..524	CDD:273327	127/542 (23%)
Sv2b	NP_001103223.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..73		4/14 (29%)
		synapt_SV2	8..683	CDD:130366	155/652 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8715
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920