Protein Alignment CG31272 and SLC22A23

DIOPT Version :9

• Sequence 1: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: XP_011513103.1
• Gene: SLC22A23 / 63027
• HGNCID: 21106
• Length: 710
• Species: Homo sapiens
• Alignment Length: 487
• Identity: 95/487 - (19%)
• Similarity: 162/487 - (33%)
• Gaps: 142/487 - (29%)

  Fly   107 GMTISAIAWGYLADTKGRKKILYWGYLIDAVCVFG--SALSQNFSMLVMFKFLGGLVVNGPAAVL 169
            |:....:..|.:||..||:.:|.:..:.  :.:||  .|||.|.:|....:|..|..:.|....|
Human   263 GLIFGYLITGCIADWVGRRPVLLFSIIF--ILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTL 325

  Fly   170 FTYLTEMHGPKHRSSVLMIVGMVTSTATVSLPLLAWGIFPRDWDFEFWGLQVHSWQIFLFVLGIP 234
            :....|:..|..|..:.|:...|.......:|.||  ...||            ||:...::..|
Human   326 YALRIELCPPGKRFMITMVASFVAMAGQFLMPGLA--ALCRD------------WQVLQALIICP 376

  Fly   235 SLISGLIFCSMPESPRFLMAQGRNEEALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQNEV 299
            .|:..|.:...|||.|:|||..:.|.|.:........|...|:..  ||.:|.|:.
Human   377 FLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGD--IKGVIPELE--------- 430

  Fly   300 IYTIEEKSGEVPTKRQSRTLAESLRAGLQQMKPLVRKPLLGLAICCYVMQFGIFLGMNTIRLWLP 364
                                           |.|.|:|    ...|.|...|      |..||.
Human   431 -------------------------------KELSRRP----KKVCIVKVVG------TRNLWK- 453

  Fly   365 QLFASMAEYEALHAGDGLDVSMCTILEFSVNQTAETALNYADACS----EPKV-ISMDMYLNNII 424
                                   .|:...||......:::..|.|    |.|| :..:.|.:...
Human   454 -----------------------NIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYT 495

  Fly   425 VSATGFVGYFFAGGILRALGPKRMMTYGLFLSGTFGLMLYFSVSSLMTLI--------------- 474
            .::...|.......::|.||.:.            ||:|:..:::|.:|:
Human   496 TASIALVSCLAMCVVVRFLGRRG------------GLLLFMILTALASLLQLGLLNLIGKYSQHP 548

  Fly   475 -------VSATF---LTITGIAVSSLLGAVVALF-----PTQLRTVVVAIAMMCGRFGALSGNLL 524
                   |...|   .:|.|:..|..:|::...|     ||.:|...:.:.:....||.|:..::
Human   549 DSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPII 613

  Fly   525 FPVFVQTGCLPPFIMVSSVLILSGILSISLPD 556
             .:..|.|.....|:.:...::..|..:.||:
Human   614 -ELHNQKGYFLHHIIFACCTLICIICILLLPE 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	93/484 (19%)
		2A0115	74..524	CDD:273327	89/453 (20%)
SLC22A23	XP_011513103.1	2A0119	<243..652	CDD:273328	95/487 (20%)
		MFS	259..>388	CDD:119392	33/140 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153277
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930