DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31272 and sv2

DIOPT Version :9

Sequence 1:	NP_650013.3	Gene:	CG31272 / 326130	FlyBaseID:	FBgn0051272	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_009296040.1	Gene:	sv2 / 570651	ZFINID:	ZDB-GENE-000607-80	Length:	522	Species:	Danio rerio

Alignment Length:	557	Identity:	160/557 - (28%)
Similarity:	267/557 - (47%)	Gaps:	54/557 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 IPEKSKGLENDKDADGNSDSTAEAEATPTEEGSATFDKAIEGAGFGIFNLMLLIVSIPAQSAAIF 74
            :|.:|:   .|.:...:|.:..|.:...:.....|:::|:|.||||:|:.:||:|...|.::...
Zfish     1 MPRQSR---EDTEPLLSSANNEEDDEQASCRKKLTYEEAVEKAGFGLFHWLLLVVCGWANASDAV 62

  Fly    75 ESSSMSYILPIAECDLRLTLEDKGVLNAVAYAGMTISAIAWGYLADTKGRKKILYWGYLIDAVCV 139
            |...:|::||.|.|||:|:..|.|:|.|..:.||.:....||:|||.:||:.:|.....::.  .
Zfish    63 EILCVSFLLPTARCDLQLSSADMGILTASIFLGMMVGGCVWGFLADRRGRRSVLVVSLAVNG--T 125

  Fly   140 FG--SALSQNFSMLVMFKFLGGLVVNGPAAVLFTYLTEMHGPKHRSSVLMIVGMVTSTATVSLPL 202
            ||  ::|:..|.:.::.:|..|:.|.|...|:|:|.:|......|.:::..:........:....
Zfish   126 FGAVASLAPTFWLFLLLRFFSGVGVGGSIPVIFSYFSEFQPCLRRGAMISALATFWMAGNILAAG 190

  Fly   203 LAWGIFPRDWDFEFWG-LQVHSWQIFLFVLGIPSLISGLIF-CSMPESPRFLMAQGRNEEALQAF 265
            :||.:.||......|| |...||::|:.:..||||.|.||| ..|||||:|||..||..|||..|
Zfish   191 VAWLVIPRTSLHADWGWLDFQSWRLFVVLCSIPSLSSALIFRLFMPESPKFLMEAGREMEALSVF 255

  Fly   266 KQIYHVNTRKPKDSYPIKALI-----QEVPNRKAAQNEVIYTIEEKSGEVPTKRQSRT--LAESL 323
            ::||.:|.|.....:|:..|:     .||.||                  |:...||:  ....|
Zfish   256 QKIYKLNNRGATKPFPVSGLMIRPKDDEVKNR------------------PSHSSSRSQRFINQL 302

  Fly   324 RAGLQQMKPLVRKPLLGLAICCYVMQFGIFLGMNTIRLWLPQLFASMAEYEALHAGDGLDVSMCT 388
            ...|..:|.|..:||...::...::.|.|..|...:.:|.|:||.        .|.||  .|.|.
Zfish   303 TQALVPLKQLFVRPLASRSVVLVIIFFCISFGYYGLWMWFPELFK--------RAEDG--GSPCA 357

  Fly   389 ILEFSVNQTAETALNYADACSEPKVISMDMYLNNIIVSATGFVGYFFAGGILRALGPKRMMTYGL 453
              ..|..|.||....|.        :...:|:...|.:|:...|..|...::..:|.|.:::..|
Zfish   358 --NMSRAQNAENEKCYP--------VKTAVYMEGFITAASNLPGNIFTILLMDRIGGKILLSVSL 412

  Fly   454 FLSGTFGLMLYFSVSSLMTLIVSATFLTITGIAVSSLLGAVVALFPTQLRTVVVAIAMMCGRFGA 518
            .:||....::|...:...:||||..|..::.|:.::|......|:|||||:..:.:....||..|
Zfish   413 LVSGVSVFVIYVVKTKTQSLIVSCVFSGVSVISWNALDVVGTELYPTQLRSSALGVFTGVGRVAA 477

  Fly   519 LSGNLLFPVFVQTGCLPPFIMVSSVLILSGILSISLP 555
            :.||::|...|.:.|..|.:||..:|:..|:.::.||
Zfish   478 IMGNVVFGQLVDSSCAVPLLMVCVLLLAGGLAALWLP 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	144/503 (29%)
CG31272	NP_650013.3	2A0115	74..524	CDD:273327	133/460 (29%)
sv2	XP_009296040.1	2A0115	33..488	CDD:273327	145/494 (29%)
sv2	XP_009296040.1	MFS	50..500	CDD:119392	141/489 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920