Protein Alignment CG31272 and SVOP

DIOPT Version :10

• Sequence 1: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_061181.1
• Gene: SVOP / 55530
• HGNCID: 25417
• Length: 548
• Species: Homo sapiens
• Alignment Length: 585
• Identity: 126/585 - (21%)
• Similarity: 218/585 - (37%)
• Gaps: 143/585 - (24%)

  Fly    20 DKDADGNSDSTAEA-----EATPTEEGSA-----------TF--DKAIEGAGFGIFNLMLLIVSI 66
            |..|.|..:...|.     ||...::|:|           ||  :.|:|..|||.|...|.:::.
Human    27 DDTASGEHEVQIEGVHVGLEAVELDDGAAVPKEFANPTDDTFMVEDAVEAIGFGKFQWKLSVLTG 91

  Fly    67 PAQSAAIFESSSMSYILPIAECDLRLTLEDKGVLNAVAYAGMTISAIAWGYLADTKGRK---KI- 127
            .|..|...|...:|.:.|...|:.||......:|.:|.:.||..|:..||.::|..|||   ||
Human    92 LAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKIS 156

  Fly   128 ----LYWGYLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNG-PAAVLFTYLTEMHGPKHRSSVLM 187
                ||:|.|        ||.:..:|.:::.:.|.|..:.| |.:|  |...|....|.|:..::
Human   157 VLWTLYYGIL--------SAFAPVYSWILVLRGLVGFGIGGVPQSV--TLYAEFLPMKARAKCIL 211

  Fly   188 IVGMVTSTATVSLPLLAWGIFPRDWDFEFWGLQVHSWQIFLFVLGIPSLISGLIFCSMPESPRFL 252
            ::.:..:..||...:||..:.|.           ..|:..|.:..:|.|:..::...:|||.|:.
Human   212 LIEVFWAIGTVFEVVLAVFVMPS-----------LGWRWLLILSAVPLLLFAVLCFWLPESARYD 265

  Fly   253 MAQGRNEEALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQN-------EVIYTIEEKSGEV 310
            :..|..|:|:...|:|                         |.:|       ::|.:.:|..|
Human   266 VLSGNQEKAIATLKRI-------------------------ATENGAPMPLGKLIISRQEDRG-- 303

  Fly   311 PTKRQSRTLAESLRAGLQQMKPLVRKPLLGLAICCYVMQFGIFLGMNTIRLWLPQLFASMAEY-- 373
                              :|:.|                |.......|:.||......:.:.|
Human   304 ------------------KMRDL----------------FTPHFRWTTLLLWFIWFSNAFSYYGL 334

  Fly   374 -----EALHAGDGLDVSMCTILEFSVNQTAETALNYADACSEPKVISMDMYLNNIIVSATGFVGY 433
                 |...|||     :|.|........|:.:|    ||   :.:|.:.|::.:..:.:.|.|.
Human   335 VLLTTELFQAGD-----VCGISSRKKAVEAKCSL----AC---EYLSEEDYMDLLWTTLSEFPGV 387

  Fly   434 FFAGGILRALGPKRMMTYGLFLSGTFGLMLYFSVS-SLMTLIVSATFLTITGIAVSSLLGAVV-- 495
            .....|:..||.|:.|.....:.....|:|:..|. :::||::......|:|    ....|.|
Human   388 LVTLWIIDRLGRKKTMALCFVIFSFCSLLLFICVGRNVLTLLLFIARAFISG----GFQAAYVYT 448

  Fly   496 -ALFPTQLRTVVVAIAMMCGRFGALSGNLLFPVFVQTGCLPPFIMVSSVLILSGILSISLPDPAK 559
             .::||..|.:.:.......|.|||....:..|.:::.......:.|...:|:.:.|..||...|
Human   449 PEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASCFLPIETK 513

  Fly   560  559
            Human   514  513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	synapt_SV2	15..556	CDD:130366	124/580 (21%)
SVOP	NP_061181.1	MFS_SVOP	87..509	CDD:340999	106/519 (20%)