DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31272 and Svopl

DIOPT Version :9

Sequence 1:	NP_650013.3	Gene:	CG31272 / 326130	FlyBaseID:	FBgn0051272	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_008761085.2	Gene:	Svopl / 500085	RGDID:	1566053	Length:	446	Species:	Rattus norvegicus

Alignment Length:	546	Identity:	117/546 - (21%)
Similarity:	201/546 - (36%)	Gaps:	148/546 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 GFGIFNLMLLIVSIPAQSAAIFESSSMSYILPIAECDLRLTLEDKGVLNAVAYAGMTISAIAWGY 117
            || .|.|:|.:|.       ..|...::.:.|:..|:.:|.......:..:.:.|..:|:|.:|.
  Rat     2 GF-CFLLLLQVVE-------AMEIMLIAVVSPVIRCEWQLENWQVAFVTTMVFFGYMVSSILFGL 58

  Fly   118 LADTKGRKKILYWGYLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNGPAAVLFTYLTEMHGPKHR 182
            |||..||.|||...:|..|.....::.|.::...|..:.:.|..|:|.|..|. ..||....|:|
  Rat    59 LADRYGRWKILLLSFLWGAYFSLLTSFSPSYIWFVFLRTMVGCGVSGHAQGLI-IKTEFLPTKYR 122

  Fly   183 ------SSVLMIVG--MVTSTATVSLPLLAWGIFPRDWDFEFWGLQVHSWQIFLFVLGIPSLISG 239
                  |.|..:.|  ::.|.|:|.:|.:.|.          |.:::.|         ||.:|..
  Rat   123 GYMLPLSQVFWLAGSLLIISMASVVIPTIGWR----------WLIRIAS---------IPGIILI 168

  Fly   240 LIFCSMPESPRFLMAQGRNEEALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQNEVIYTIE 304
            :.|..:|||.||.::.|..:.||...:.|..:|          ::::.|        ..::..|.
  Rat   169 MAFKFIPESARFNVSTGNTQAALDTLESIAKMN----------RSVMPE--------GRLVEPIL 215

  Fly   305 EKSGEVPTKRQSRTLAESLRAGLQQMKPLVRKPLLGLAICCYVMQFGIFLGMNTIRLWLPQLFAS 369
            ||.|......:|:.|                                    ..|:::|:..|..|
  Rat   216 EKRGRFADLLESKYL------------------------------------RTTLQIWIIWLGIS 244

  Fly   370 MAEYEALHAGDGLDVSMCTILEFSV------NQTAETALNYADACSEPKVISMDMY----LNNII 424
            .|.|       |:.::...:||..:      ....|...|..||..........|:    ...:|
  Rat   245 FAYY-------GVILASAELLERDLVCGSKSESEPEVVENMGDAEEGRSPCYCHMFAPSDYRTMI 302

  Fly   425 VSATGFVGYFFAGGILRALGPKRMMTYGL-FLSGTFGLMLYFSVSSLMTLIVSATFLTITGIAVS 488
            :|..|.:          ||.|..::  |: ||    |..|..|:    |:..:|.|..:..|..|
  Rat   303 ISTLGEI----------ALNPLNIL--GINFL----GRRLSLSI----TMGCTALFFLLLNICTS 347

  Fly   489 S--------LLGAVVA------------LFPTQLRTVVVAIAMMCGRFGALSGNLLFPVFVQTGC 533
            |        :|.|:||            ::||.:|.:.:..:....|.||:....:..|.:....
  Rat   348 SAGLIGFLFMLRALVAANFNTIYIYTAEVYPTPMRALGMGTSGSLCRIGAMVAPFISQVLMSASF 412

  Fly   534 LPPFIMVSSVLILSGILSISLPDPAK 559
            |....:.|||.::..|.:.:||...|
  Rat   413 LGALCLFSSVCVVCAISAFTLPIETK 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	109/531 (21%)
CG31272	NP_650013.3	2A0115	74..524	CDD:273327	102/488 (21%)
Svopl	XP_008761085.2	MFS_SVOPL	3..434	CDD:341000	113/539 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347153
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940