DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31272 and CG12783

DIOPT Version :9

Sequence 1:	NP_650013.3	Gene:	CG31272 / 326130	FlyBaseID:	FBgn0051272	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001262644.2	Gene:	CG12783 / 42019	FlyBaseID:	FBgn0038448	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	520	Identity:	139/520 - (26%)
Similarity:	222/520 - (42%)	Gaps:	59/520 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 FDKAIEGAGFGIFNLMLLIVSIPAQSAAIFESSSMSYILPIAECDLRLTLEDKGVLNAVAYAGMT 109
            ||..:|..|||..:|...:.....|...|.|:..|..|.|.|.||||:.......|.|..:.|:.
  Fly     4 FDSVMEDIGFGRVHLFATVTLGLLQMLTIQETMGMGIIGPAAVCDLRMNEAQLASLTAAGFMGII 68

  Fly   110 ISAIAWGYLADTKGRKKILYWGYLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNGPAAVLFTYLT 174
            .|:..|||:.|.|||:..|.....|..:|...|..:..|:...:.:|:..:.|.||:.|..|||:
  Fly    69 CSSYFWGYITDKKGRRWTLLRTITISNLCSLASMFTVTFTGFFVMRFITCIFVAGPSFVAATYLS 133

  Fly   175 EMHGPKHRSSVLMI--VGMVTSTATVSLPLLAWG-IFPRDWDFEF-----WGLQVHSWQIF--LF 229
            |.  ..||..|..|  :.|.|..|.:|.|  ||. :|......||     ..|.:..|::.  |:
  Fly   134 EF--CSHRIMVRSITHLYMFTGFAMISCP--AWATLFLSSGLIEFEEKLVGSLTLRPWRVLGCLY 194

  Fly   230 VLGIPSLISGLIFCSMPESPRFLMAQGRNEEALQAFKQIYHVNTRKPKDSYPIKALIQ-----EV 289
            :|  |.:::.|:...:||||:||:..|..:..|...:.|...||.:......:|.|:.     :|
  Fly   195 IL--PGVVAFLLLLLLPESPKFLLMIGETKRGLDTMEWISRKNTGRTLSEDQMKRLLAYQEHVQV 257

  Fly   290 PNRKAAQNEVIYTIEEKSGEVPTKRQSRTLAESLRAGLQQMKPLVRKPLLGLAICCYVMQFGIFL 354
            ..||..||                        ..|:.|....||||||..|...|..::.|.:.|
  Fly   258 KRRKEHQN------------------------FFRSMLDDAMPLVRKPYGGYFTCVCMVMFVLGL 298

  Fly   355 GMNTIRLWLPQLFASMAEYEALHAGDGLDVSMCTILEFSVNQTA---ETALNYADACSEPKVISM 416
            ..:.:.:|    :.:|.....:..|:...::.|.:|  .|.:|.   ||..:....||:    |.
  Fly   299 LTHGLGIW----YTAMRNRCNMRQGNTNGMTFCQVL--FVPETGPFIETESDLDVVCSD----SF 353

  Fly   417 DMYLNNIIVSATGFVGYFFAGGILRALGPKRMMTYGLFLSGTFGLMLYFSVSSLMTLIVSATFLT 481
            ..:.::.::.....|.|..:...|..:..|.|..:.|..|.|||.:|.|:.:.::.|......:.
  Fly   354 KGFNDSFVLGFVYVVLYNISWASLFCVHKKVMFVFSLVASSTFGFLLIFATNHMLQLFSLVFLIA 418

  Fly   482 ITGIAVSSLLGAVVALFPTQLRTVVVAIAMMCGRFGALSGNLLFPVFVQTGCLPPFIMVSSVLIL 546
            ..||.:..|.|:::...||.||...:.|::|..|.||..|.:|....:|..| ..|::..|:|.|
  Fly   419 FPGIIIGLLGGSLLVFVPTYLRGKALCISLMWCRCGAAFGAMLVGSKIQYNC-ELFLLAISILPL 482

Fly 547 546
Fly 483 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	132/503 (26%)
CG31272	NP_650013.3	2A0115	74..524	CDD:273327	123/467 (26%)
CG12783	NP_001262644.2	synapt_SV2	<2..>310	CDD:130366	94/339 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458194
Domainoid	1	1.000	45	1.000	Domainoid score	I3556
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	6.000