DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31272 and slc22a7b.1

DIOPT Version :9

Sequence 1:	NP_650013.3	Gene:	CG31272 / 326130	FlyBaseID:	FBgn0051272	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_021322800.1	Gene:	slc22a7b.1 / 393320	ZFINID:	ZDB-GENE-040426-1311	Length:	560	Species:	Danio rerio

Alignment Length:	599	Identity:	124/599 - (20%)
Similarity:	216/599 - (36%)	Gaps:	167/599 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NIKTAIPEKSKGLENDKDADGNSDSTAEAEATPTEEGSATFDKAIEGAGFGIFNLMLLIVSIPAQ 69
            |...|||.....: :..||||..:.|.:..                           ||||:|||
Zfish    49 NFIAAIPSHHCDI-SSLDADGLGNLTQKER---------------------------LIVSVPAQ 85

  Fly    70 ------SAAIFE--------SSSMSYILPIAEC-----------------DLRLTLEDKGVLNAV 103
                  |..:|.        :||.|..||:.||                 ...|..:.:|:..|.
Zfish    86 EDGTPASCHMFAHPQFQLLINSSSSSALPVVECQNGWHFDNSTFISTLATQFDLVCDKRGLAKAS 150

  Fly   104 A---YAGMTISAIAWGYLADTKGRKKILYWGYLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNGP 165
            |   :.|:...|:.:|.|.|..||:.:|...|:...|....||.|.::.|...|:||.||.:.|.
Zfish   151 ATIFFVGVMCGAVFFGVLCDKYGRRSMLLVSYVFSIVFSVTSAFSSSYIMFAAFRFLTGLALTGI 215

  Fly   166 AAVLFTYLTEMHGPKHRSSVLMIVGMVTSTATVSLPLLAWGIFPRDWDFEFWGLQVHSWQIFLFV 230
            :.:......|....|||:.:.:...|..|...:   |||        .|.|   .|..|::.:.:
Zfish   216 SNISVVLSIEWVDTKHRTFMGLFGSMSWSIGNM---LLA--------GFAF---MVTDWRLLIVI 266

  Fly   231 LGIPSLISGLIFCSMPESPRFLMAQGRNEEALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAA 295
            :..|..::...:..:|:|.|:|:|.|:.|   .|:|.::...|...:..:..:.        |..
Zfish   267 VTAPLFLATATWWWIPDSARWLIANGKTE---TAYKYLHKCATFNQRLDFTSRV--------KPE 320

  Fly   296 QNEVIYTIEEKSGEVPTKRQSRTLAESLRAGLQQMKPLVRKPLLGLAICCYVMQFGIFLGMNTIR 360
            ....:.|::.:.       .|.|..:.::.      |.:||    |.:...::.:|:
Zfish   321 TLSTVVTVDHRG-------HSYTYLDLVKT------PQLRK----LTLFTGIVWYGV-------- 360

  Fly   361 LWLPQLFASMAEYEALHAGDGLDVSMCTILEFSVNQTAETALNYADACSEPKVISMDMYLNNIIV 425
                   ||                  |....|:|.|.               ..:|.||.:.|.
Zfish   361 -------AS------------------TYYGISLNITG---------------FGLDPYLTHFIY 385

  Fly   426 SATGFVGYFFAGGILRALGPKRMMTYGLFLSGTFGLMLYFSVSSLMTLIVSATFLTI-----TGI 485
            :|............|..:|.:...|..|.|:| |.:::     :::|.....||.|:     .|:
Zfish   386 AAIEVPAKILVYFSLNKVGRRNTQTGTLVLTG-FCILI-----NIITPTEYWTFRTVIAVLGKGL 444

  Fly   486 AVSSLLGAVV---ALFPTQLRTVVVAIAMMCGRFGALSGNLLFPVFVQTGCLPPFIMVSSVLILS 547
            :.:|....::   .|:||.:|...:.......|.|| |.:.|..:......|.|.::..|:.|..
Zfish   445 SEASFTTVILYTTELYPTVMRQNGLGFTNFMARMGA-SISPLIMLLEDIWKLLPEVIFCSMAIFC 508

  Fly   548 GILSISLPDPAKAT 561
            ||:::.||:...|:
Zfish   509 GIIALLLPETNNAS 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	112/534 (21%)
CG31272	NP_650013.3	2A0115	74..524	CDD:273327	97/485 (20%)
slc22a7b.1	XP_021322800.1	Sugar_tr	22..526	CDD:331684	124/599 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588850
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840