Protein Alignment CG31272 and SLC22A25

DIOPT Version :9

• Sequence 1: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: XP_016873173.1
• Gene: SLC22A25 / 387601
• HGNCID: 32935
• Length: 577
• Species: Homo sapiens
• Alignment Length: 620
• Identity: 123/620 - (19%)
• Similarity: 209/620 - (33%)
• Gaps: 218/620 - (35%)

  Fly     3 EKNIKTAIPEKSKGLENDK----DADGNSDSTAEAEATPTEEGSATFDKAIEGAGFGIFNLMLLI 63
            :.|::   |||.:...:.:    ..:|...:|:|.:..|..:|
Human    80 DSNLR---PEKCRRFVHPQWKLIHLNGTFPNTSEPDTEPCVDG---------------------- 119

  Fly    64 VSIPAQSAAIFESSSMSYILPIAECDLRLTLEDKGVLNAVA----YAGMTISAIAWGYLADTK-- 122
                    .:::.||....: :.:.||   :.:...||:||    .|||.:....:|:|:|.|
Human   120 --------WVYDQSSFPSTI-VTKWDL---VCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRKPL 172

  Fly   123 ----------------------------GRKKILYWGYLIDAVCVFGSALSQNFSMLVMFKFLGG 159
                                        |||.:|.|.||..|:....:|.:....:....:||.|
Human   173 SSPNHVSTDCDEGLEVPIAIHQHHVFWFGRKFVLRWSYLQLAIVGTCAAFAPTILVYCSLRFLAG 237

  Fly   160 LVVNGPAAVLFTYLTEMHGPKHRSSVLMIVGMVT---------------STATVSLPLLAWGIFP 209
                   |..|:.:.        ::||:||..:|               |...::|..||:.|
Human   238 -------AATFSIIV--------NTVLLIVEWITHQFCAMALTLTLCAASIGHITLGSLAFVI-- 285

  Fly   210 RDWDFEFWGLQVHSWQIFL-FVLGIPSLISGLIFCSMPESPRFLMAQGRNEEALQAFKQIYHVNT 273
            ||             |..| .|:..|..:..|....:.||.|:|:...:.||.|:..::..|.|.
Human   286 RD-------------QCILQLVMSAPCFVFFLFSRWLAESARWLIINNKPEEGLKELRKAAHRNG 337

  Fly   274 RKPKDSYPIKALIQEVPNRKAAQNEVIYTIEEKSGEVPTKRQSRTLAESLRAGLQQMKPLVRKPL 338
            .|..:.    .|..||......|            |:...::..:|.|           |:|.|.
Human   338 MKNAED----ILTMEVLKSTMKQ------------ELEAAQKKHSLCE-----------LLRIPN 375

  Fly   339 LGLAICCYVMQFGIFLGMNTIRLWLPQLFASMAEYEALHAGDGLDV-----SMCTILEFSVNQTA 398
            :...||  .:.|..|  .:||..|...|...       |.|:.:.:     ...|:|   .|..|
Human   376 ICKRIC--FLSFVRF--ASTIPFWGLTLHLQ-------HLGNNVFLLQTLFGAVTLL---ANCVA 426

  Fly   399 ETALNYADACSEPKVISMDMYLNNIIVSATGFVGYFFAGGILRALGPKRMMTYGLFLSGTFGLML 463
            ..|||:           |...|:.:::                           :||..|..|.:
Human   427 PWALNH-----------MSRRLSQMLL---------------------------MFLLATCLLAI 453

  Fly   464 YFSVSSLMTL-IVSATFLTITGIAVSSLLGAVVA------LFPTQLRTVVVAIAMMCGRFGALSG 521
            .|....:.|| :|.||.    |:..:| ||...:      |.|:.:|.....|.......|....
Human   454 IFVPQEMQTLRVVLATL----GVGAAS-LGITCSTAQENELIPSIIRGRATGITGNFANIGGALA 513

  Fly   522 NLLFPVFVQTGCLPPFIMVSSVLILSGILSISLPD 556
            :|:..:.:.:..| |:|:.....||||::.:.||:
Human   514 SLMMILSIYSRPL-PWIIYGVFAILSGLVVLLLPE 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	112/554 (20%)
		2A0115	74..524	CDD:273327	104/511 (20%)
SLC22A25	XP_016873173.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153568
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840