DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31272 and CG4324

DIOPT Version :9

Sequence 1:	NP_650013.3	Gene:	CG31272 / 326130	FlyBaseID:	FBgn0051272	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001286807.1	Gene:	CG4324 / 37830	FlyBaseID:	FBgn0034956	Length:	478	Species:	Drosophila melanogaster

Alignment Length:	558	Identity:	117/558 - (20%)
Similarity:	221/558 - (39%)	Gaps:	99/558 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NIKTAIPEKSKGLENDKDADGNSDSTAEAEATP-TEEGSATFDKAIEGAGFGIFNLML-LIVSIP 67
            |...|:|..:.....|..:     ||.|.:... ..:.:.|..:||...|||.|::.| |:|.:.
  Fly     6 NEPAALPSPANLAPRDVHS-----STLELKTVSINPDDTYTVQQAINAFGFGWFHVKLSLLVGLC 65

  Fly    68 AQSAAIFESSSMSYILPIAECDLRLTLEDKGVLNAVAYAGMTISAIAWGYLADTKGRKKIL-YWG 131
            ..|.:: |.:.:|.:.|...|:..:|...:..:..|.:.||.:|:..|..|::..|||..| .:|
  Fly    66 WMSDSM-EMAILSILGPSLFCEWNVTKFQQASVTTVVFLGMMLSSSFWTQLSNRYGRKSALTLFG 129

  Fly   132 YLIDAVCVFGSALSQNFSMLVMFKFLGGLVVN-GPAAVLFTYLTEMHGPKHRSSVLMIVGMVTST 195
            .|:....:. |:::.:::.|:..:.|.|..:. .|.:|  |...|....||:...::::....:.
  Fly   130 VLLVLYSIL-SSVAPSYAWLLTLRGLVGFAIGCVPQSV--TLYAEFLPTKHKGKCVVLMDCFWAL 191

  Fly   196 ATVSLPLLAWGIFPRDWDFEFWGLQVHSWQIFLFVLGIPSLISGLIFCSMPESPRFLMAQGRNEE 260
            ......:||..::|      ::|     |:..|.:...|.||..::...:.||.|:....|.|::
  Fly   192 GACFEVVLALVVYP------YYG-----WRGLLALSATPLLIFTILSPWLSESARYYSYNGHNDK 245

  Fly   261 ALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQNEVIYTIEEKSGEVPTKRQSRTLAESLRA 325
            |::..:||.|.|.|            ..:..|..|.:|                  .:.|||.|:
  Fly   246 AIKVLEQIAHNNKR------------HMLMGRLMADDE------------------PSCAESFRS 280

  Fly   326 GLQQMKPLVRKPLLGLAICCYVMQFGIFLGMNTIRLWLPQLFASMAEYEALHAGDGLDVSMCTIL 390
            .|...                       |...||.||...|.::...|       ||   :....
  Fly   281 LLSPS-----------------------LYRTTILLWFLWLASAFCYY-------GL---VLVTT 312

  Fly   391 EFSVNQTAETALNYADACSEPKVISMDMYLNNIIVSATGFVGYFFAGGILRALGPKR--MMTYGL 453
            |..|.:..|:..|      |........:::.:.::.:.|.|......:::..|.|:  ::.|..
  Fly   313 ELLVARNKESHPN------ECVTFMTSDFMDLLWITLSEFPGILLTIKVVKLFGKKKTIVLQYLA 371

  Fly   454 FLSGTFGLMLYFS-VSSLMTLIVSATFLTITGIAVSSLLGAVVALFPTQLRTVVVAIAMMCGRFG 517
            .:..|..||...| .|:.:||.::..  ||:|| ..::......::|..||:|.|:...:..|.|
  Fly   372 LVLCTLVLMSVESRFSTSVTLFIARG--TISGI-FQAIYVYTPEIYPAALRSVGVSGCSVLARLG 433

  Fly   518 ALSGNLLFPVFVQTGCLPPFIMVSSVLILSGILSISLP 555
            |:....:..|.:.:..:......:.|.:|:.|..:.||
  Fly   434 AMLTPFVAQVLMDSSRIQAMSTYAIVGLLASIACVFLP 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	100/497 (20%)
CG31272	NP_650013.3	2A0115	74..524	CDD:273327	93/454 (20%)
CG4324	NP_001286807.1	2A0119	10..476	CDD:273328	116/554 (21%)
CG4324	NP_001286807.1	MFS	60..471	CDD:119392	100/497 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458126
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940