Protein Alignment CG31272 and Slc22a12

DIOPT Version :10

• Sequence 1: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: XP_063125948.1
• Gene: Slc22a12 / 365398
• RGDID: 621628
• Length: 643
• Species: Rattus norvegicus
• Alignment Length: 555
• Identity: 123/555 - (22%)
• Similarity: 213/555 - (38%)
• Gaps: 159/555 - (28%)

  Fly    24 DGNSDST--AEAEATPTEEG----SATFDKAIEGAGFGIFNLMLLIVSIPAQSAAIFESSSMSYI 82
            :.|:.:|  ::|:..|.|:|    .:||...|           :....:...|.|         :
  Rat   190 ESNTTATNWSDADTEPCEDGWVYDHSTFRSTI-----------VTTWDLVCDSQA---------L 234

  Fly    83 LPIAECDLRLTLEDKGVLNAVAYAGMTISAIAWGYLADTKGRKKILYWGYLIDAVCVFGSALSQN 147
            .|:|:              ::..||:.:.|...|:.:|..||:::|.|.||:.:|....:||...
  Rat   235 RPMAQ--------------SIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTIAALMPT 285

  Fly   148 FSMLVMFKFL-----GGLVVNGPAAVLFTYLTEMHGPKHRSSVLMIVGMVTSTATVSLPLLAWGI 207
            |.:..:|:||     .|:::| .|::|..:.:...||    .::.:..:..|...|....:|:|
  Rat   286 FPLYCLFRFLVASAVAGVMMN-TASLLMEWTSAQAGP----LMMTLNALGFSFGQVLTGSVAYG- 344

  Fly   208 FPRDWDFEFWGLQVHSWQIFLFVLGIPSLISGLIFCSMPESPRFLMAQGRNEEALQAFKQIYHVN 272
                         |.||::....:..|..:..:....:|||.|:|:..||.:::|:..:::..||
  Rat   345 -------------VRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGRLDQSLRELQRVAAVN 396

  Fly   273 TRKPK-DSYPIKAL---IQEVPNRKAAQNEVIYTIEEKSGEVPTKRQSRTLAESLRAGLQQMKPL 333
            .||.: |:..::.|   :||.||...|                          ..|.|.....|.
  Rat   397 RRKAEADTLTVEVLRSAMQEEPNGNQA--------------------------GARLGTLLHTPG 435

  Fly   334 VRKPLLGLAICCYVMQFGIFLGMNTIRLWLPQLFASMAEYEALHAGDGLDVSMCTILEFS----- 393
            :|.......:|.:...| .|.|   :.|.|..|.:::...:||.....|.|.|.::|..|
  Rat   436 LRLRTFISMLCWFAFGF-TFYG---LALDLQALGSNIFLLQALIGIVDLPVKMGSLLLLSRLGRR 496

  Fly   394 VNQTAETALNYADACSEPKVISMDMYLNNIIVSATGFVGYFFAGGILRALGPKRMMTYGLFLSGT 458
            :.|.:...|  ...|          .|.||:|..        ..||||:    .:...||   |:
  Rat   497 LCQASSLVL--PGLC----------ILANILVPR--------EMGILRS----SLAVLGL---GS 534

  Fly   459 FGLMLYFSVSSLMTLIVSATFLTITGIAVSSLLGAVVALFPTQLRTVVVAIAMMCGRFGALSGNL 523
            .|                |.|..:|  ..||      .||||.:|...|.:..:..|.||:.|.|
  Rat   535 LG----------------AAFTCVT--IFSS------ELFPTVIRMTAVGLGQVAARGGAMLGPL 575

  Fly   524 --LFPVFVQTGCLPPFIMVSSVLILSGILSISLPD 556
              |..|:   |...|.::...|.:|||:.::.||:
  Rat   576 VRLLGVY---GSWLPLLVYGVVPVLSGLAALLLPE 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	synapt_SV2	15..556	CDD:130366	122/553 (22%)
Slc22a12	XP_063125948.1	None