DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31272 and CG3690

DIOPT Version :9

Sequence 1:	NP_650013.3	Gene:	CG31272 / 326130	FlyBaseID:	FBgn0051272	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001284764.1	Gene:	CG3690 / 31047	FlyBaseID:	FBgn0040350	Length:	558	Species:	Drosophila melanogaster

Alignment Length:	553	Identity:	256/553 - (46%)
Similarity:	370/553 - (66%)	Gaps:	10/553 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 ENDKDADGNSDSTAEAEA--TPTEEGSATFDKAIEGAGFGIFNLMLLIVSIPAQSAAIFESSSMS 80
            |..:..|.....|||.:.  .|.:|.:|.|:.||:.||||:||::||:.::||....::|:|:||
  Fly     3 EPSESGDPKPHKTAEHQIGDPPQKEAAADFEAAIDAAGFGMFNILLLVAAVPAAMGTVYETSTMS 67

  Fly    81 YILPIAECDLRLTLEDKGVLNAVAYAGMTISAIAWGYLADTKGRKKILYWGYLIDAVCVFGSALS 145
            ||||.|||||:|:|.|||:|||:.||||..||:.||||||.|||:.:|..||..|.:||.|.|||
  Fly    68 YILPSAECDLKLSLLDKGILNAITYAGMISSAVLWGYLADIKGRRNLLIVGYAADTICVLGGALS 132

  Fly   146 QNFSMLVMFKFLGGLVVNGPAAVLFTYLTEMHGPKHRSSVLMIVGMVTSTATVSLPLLAWGIFPR 210
            |:...|::||:|||..::||.|||.|||||:||.|||..::|:||::.|.||::||.||..|.|.
  Fly   133 QSRIQLMVFKYLGGFCMSGPFAVLMTYLTELHGRKHRQRIMMMVGIMFSIATLTLPGLAMLILPE 197

  Fly   211 DWDFEFWGLQVHSWQIFLFVLGIPSLISGLIFCSMPESPRFLMAQGRNEEALQAFKQIYHVNTRK 275
            .|:.:.|.|.:.|||.|:.|..:|||:|.::|...||||:|||::|||.|||.|||.:||:|:||
  Fly   198 TWNIQIWTLSLTSWQFFVAVTALPSLLSFVLFFFFPESPKFLMSKGRNREALDAFKFMYHLNSRK 262

  Fly   276 PKDSYPIKALIQE--VPNRKAAQNEVIYT---IEEKSGEVPTKRQSRTLAESLRAGLQQMKPLVR 335
            ||||:|||.|..|  ||.:|.|::|.|.|   :..:..||.......:...|||:|..|::||..
  Fly   263 PKDSFPIKLLANEVIVPVKKHAKDETIPTELKLPTECVEVQDPENQDSKKSSLRSGFTQLRPLFT 327

  Fly   336 KPLLGLAICCYVMQFGIFLGMNTIRLWLPQLFASMAEYEALHAGDGLDVSMCTILEFSVNQTAE- 399
            ||.|||::..|::.|.:.||.||:||||||||||:.|||.|.:|:....|:|.|||:|||:|..
  Fly   328 KPYLGLSLWVYLLNFCVLLGQNTMRLWLPQLFASINEYENLMSGESQSTSICNILEYSVNRTQSQ 392

  Fly   400 -TALNYADACSEPKV-ISMDMYLNNIIVSATGFVGYFFAGGILRALGPKRMMTYGLFLSGTFGLM 462
             .|:...|...|..| |:...|.||:||:..|||.|..||.::..:|.|.:||.||.::....:.
  Fly   393 LEAVTRNDPTVECHVIITPSTYTNNLIVAGAGFVAYMLAGFLVNLVGVKLIMTSGLLIAAGCSIG 457

  Fly   463 LYFSVSSLMTLIVSATFLTITGIAVSSLLGAVVALFPTQLRTVVVAIAMMCGRFGALSGNLLFPV 527
            :|:|.|:..|:.:::.|:|:..|:.:|::.|.|:||||.|||::|::.||.||.|:|.||:.||.
  Fly   458 MYWSSSAASTVALASLFVTMGSISATSVISASVSLFPTSLRTMIVSLEMMFGRLGSLLGNIFFPA 522

  Fly   528 FVQTGCLPPFIMVSSVLILSGILSISLPDPAKA 560
            .:..||:|||:|:|:.::....::..||...||
  Fly   523 LMGLGCVPPFLMISAFMLAGCFMAAFLPLKNKA 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	234/500 (47%)
CG31272	NP_650013.3	2A0115	74..524	CDD:273327	222/457 (49%)
CG3690	NP_001284764.1	SP	42..549	CDD:273317	238/506 (47%)
		MFS	49..>195	CDD:119392	81/145 (56%)
		MFS	419..>550	CDD:119392	49/130 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445403
Domainoid	1	1.000	77	1.000	Domainoid score	I3080
eggNOG	1	0.900	-	-		E33208_3BMGJ
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	466	1.000	Inparanoid score	I3335
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27352
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	1	1.000	-	-		FOG0014384
OrthoInspector	1	1.000	-	-		mtm8715
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	10	9.910