DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31272 and Slc22a22

DIOPT Version :9

Sequence 1:	NP_650013.3	Gene:	CG31272 / 326130	FlyBaseID:	FBgn0051272	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001013969.1	Gene:	Slc22a22 / 299944	RGDID:	1304605	Length:	555	Species:	Rattus norvegicus

Alignment Length:	519	Identity:	96/519 - (18%)
Similarity:	193/519 - (37%)	Gaps:	137/519 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SEKNIKTAI-------PEKSKGLENDK----DADGNSDSTAEAEATPTEEGSATFDKAIEGAGFG 55
            :|..:|.:|       ||:.:...:.:    |::.::.::.|.|..|..:| .|:|.
  Rat    69 TEAMMKVSIPMGPNQKPEQCRRFRHPQWQFIDSNISTSNSTELETEPCLDG-WTYDH-------- 124

  Fly    56 IFNLMLLIVSIPAQSAAIFESSSMSYILPIAECDLRLTLED-KGVLNAVAYAGMTISAIAWGYLA 119
                            ::|.|:.      :.|.||....:. |....|.:.||..::|...|.::
  Rat   125 ----------------SVFTSTI------VTEWDLVCDFQSFKYYAQATSLAGHFVAAPFCGIIS 167

  Fly   120 DTKGRKKILYW---GYLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNGPAAVLFTYLTEMHGPKH 181
            |..|||.:|.:   .|.|...|   .|...|||:..:.:||.....:.........:.|....:.
  Rat   168 DRFGRKPLLMYCSLAYGILGTC---CAFVPNFSLYCVLRFLSSASASTVGMNCLILVLEETSVQW 229

  Fly   182 RSSVLMIVGMVTSTATVSLPLLAWGIFPRDWDFEFWGLQVHSWQIFLFVLGIPSLISGLIFCSMP 246
            .::|:::.|:.:||....|..||:              .:..|.:......:|..|..::||.:|
  Rat   230 HATVIVLSGLFSSTGLAGLGGLAY--------------VLSDWHLIQLTSALPYFIFFILFCWVP 280

  Fly   247 ESPRFLMAQGRNEEALQAFKQIYHVNTRKPKDSYPIKALIQEVPN---RKAAQNEVIYTIEEKSG 308
            ||.|:||..|:.::||:..::|..:|.:|.        :.|.:..   |...:.:|..|::..|
  Rat   281 ESARWLMITGKTDQALKELQRIASINGKKD--------IAQNLTTEDLRSKVKEDVCSTVKHFS- 336

  Fly   309 EVPTKRQSRTLAESLRAGLQQMKPLVRKPLLGLAICCY--------VMQFGIFLGMNTI--RLWL 363
                                 :|.::..|::...:.||        ...||:.|.::.:  .:::
  Rat   337 ---------------------IKDIIINPMIRKIVLCYSSVLFAELFSIFGLLLDVHMLGKNIFV 380

  Fly   364 PQLFASMAEYEALHAGDGLDVSMCTILEFSVNQTAETAL------NYADACSEPKVISMDMYLNN 422
            .|:...:           :|:...::..|.:.......|      ......:....:|.|||:..
  Rat   381 TQILLGV-----------IDIPSKSLTYFILRNVRRRPLIAFLLFATGGCITITMFLSEDMYVLR 434

  Fly   423 IIVSATGFVGYFFA-----GGILRALGPKRMMTYGLFLSGTFGLMLYFSVSSLMTLIVSATFLT 481
            :.:...| .|.|.|     ......|.|..:.:   .|:|     :|.||:.|.:::.:.|.:|
  Rat   435 LAIFILG-KGCFAAFISINTAYCNELSPVPLRS---TLNG-----IYISVARLASVLSALTLVT 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	84/448 (19%)
CG31272	NP_650013.3	2A0115	74..524	CDD:273327	84/436 (19%)
Slc22a22	NP_001013969.1	2A0119	11..526	CDD:273328	96/519 (18%)
Slc22a22	NP_001013969.1	MFS	127..516	CDD:119392	84/436 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347186
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840